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Background: The optimal timing of anticoagulation for patients with acute ischaemic stoke with atrial fibrillation is uncertain. We investigated the efficacy and safety of early compared with delayed initiation of direct oral anticoagulants (DOACs) in patients with acute ischaemic stroke associated with atrial fibrillation. Methods: We performed a multicentre, open-label, blinded-endpoint, paralle

This report presents an integrated simulation-based approach to study the on-site production of concrete frameworks by considering the multiple effects of weather on work task productivity and concrete curing process. The suggested approach enable to systematically study how different weather conditions and the use of climate-improved concrete in combination with different methods to shield concre

A negative association between insulin‐dependent diabetes mellitus (IDDM) and HLA‐DR, DQA1 or DQB1 was found in a large population‐based investigation of childhood‐onset patients (more than 420 patients) and controls (more than 340 controls) from Sweden. The relative risk was decreased for several haplotypes that were negatively associated with IDDM: DR15‐DQA1*0102‐DQB1*0602, DR7‐DQA1*0201‐DQB1*03

Background AAUlco:hPollecaosencsounmfirpmtitohnatcaollnhteraibduintegsletvoelesxacreersesprmesoernbtiedditcyorarnedctmly:ortality in part through the development of alcohol-related medical conditions (AMCs, including alcoholic cardiomyopathy, hepatitis, cirrhosis, etc.). The current study aimed to clarify the extent to which risk for these outcomes differs as a function of socioeconomic position (

The human lung is a complex tissue consisting of a heterogeneous mix of different structures and cells, each which a specific role that together contribute to the primary function of the organ: the gas exchange. Different mesenchymal cells populate the interstitial areas around airways and blood vessels and form the connective tissue together with the extracellular matrix. Fibroblasts constitute o

IMPORTANCE: Chronic breathlessness is common in people with chronic obstructive pulmonary disease (COPD). Regular, low-dose, extended-release morphine may relieve breathlessness, but evidence about its efficacy and dosing is needed.OBJECTIVE: To determine the effect of different doses of extended-release morphine on worst breathlessness in people with COPD after 1 week of treatment.DESIGN, SETTING

Elongation factor G (EF-G) catalyses the translocation step in protein synthesis on the ribosome. During this event the antibiotic Fusidic acid (FA) binds to and irreversably inhibits the release of the EF-G:GDP complex from the ribosome. The difficulties to elucidate the exact binding mechanism of FA to the EF-G:GDP:ribosome complex are due to the fact that FA only binds to EF-G when the factor i

Tackling climate change is one of the most pressing challenges of our time. Among the various sectors contributing to global greenhouse gas (GHG) emissions, the industrial sector plays a pivotal role, responsible for 24% of total GHG emissions. As the world’s largest emitter of CO₂, China has committed to peaking emissions by 2030 and achieving carbon neutrality by 2060. The industrial sector in C

Objectives: Posttransplant infections may lead to dire consequences in immunocompromised organ recipients. Oral foci of infection are therefore often eliminated prior to solid organ transplantation to reduce posttransplant morbidity. However, despite increasing numbers of organ transplantations the necessity of pretransplant dental treatment and its effect on transplant outcome remains uncertain.

The origins, evolutionary history and diversification of the Australian butterfly fauna are poorly known and uncertain. Two competing hypotheses have been proposed to explain the occurrence of butterflies on this isolated continental landmass. The common view is that all Australian butterflies entered the continent relatively recently from the northern hemisphere via Southeast Asia and/or mainland

The worldwide growing demand for whey proteins and derivatives requires more efficient and sustainable whey protein production processes. Whey is an important by-product from cheese manufacturing. In whey industry membrane processes such as microfiltration, ultrafiltration, nanofiltration and reverse osmosis are well-established to concentrate, fractionate and purify whey proteins as well as whey

Non-technical summary Agriculture provides many benefits to people, such as producing food and creating jobs in rural areas, but it can also have negative impacts on the environment. We analysed existing monitoring indicators for the European Union’s Common Agricultural Policy (CAP) to evaluate whether the CAP is effectively achieving multiple social and environmental goals. We found that the curr

Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anoma

CURRICULUM VITAE RICHARD ANTHONY ORAM Email: r.oram@exeter.ac.uk, D.O.B. 20-07-1980 16 Sweetbrier Lane, Exeter, UK EX13AF Tel (UK): 07792484421 http://medicine.exeter.ac.uk/about/profiles/index.php?web_id=Richard_Oram Nationality: British EDUCATION University of Exeter PhD Endogenous insulin production in Type 1 Diabetes 2014 Post Graduate Medical Certification Nephrology specialty certificate 201

https://www.ludc.lu.se/sites/ludc.lu.se/files/richard_oram_cv2016.pdf - 2026-05-05

ÖVERVAKNING AV FÅGLARNAS POPULATIONSUTVECKLING Årsrapport för 2025 ÖVERVAKNING AV FÅGLARNAS POPULATIONSUTVECKLING Årsrapport för 2025 MARTIN GREEN, FREDRIK HAAS & ÅKE LINDSTRÖM | LUNDS UNIVERSITET NATIONELL MILJÖÖVERVAKNING PÅ UPPDRAG AV NATURVÅRDSVERKET ÄRENDENNUMMER NV-25-025448 PROGRAMOMRÅDE Landskap DELPROGRAM Svensk Fågeltaxering Övervakning av fåglarnas populationsutveckling Rapportförfattar

https://www.fageltaxering.lu.se/sites/fageltaxering.lu.se/files/2026-04/arsrapport2025_del1_0.pdf - 2026-05-05

Det finns tre grundläggande nivåer vid vilken en cell kan reglera mängden av ett visst protein. Den första nivån är i vilken omfattning den kodande delen av en gen transkriberas från DNA till RNA. Den andra delen är i vilken omfattning detta RNA, även kallat messengerRNA (mRNA), translateras till ett färdigt protein. Den tredje och sista delen är i vilken utsträckning detta protein bryts ner. RNA-RNA interference (RNAi) plays a major role in regulation of gene expression in most eukaryotic organisms. On a basic level it is a protein complex named RNA induced silencing complex (RISC) that binds a RNA strand, a micro RNA (miRNA) or a small interfering RNA (siRNA), which guides it to its intended target, an mRNA. The RISC then disrupts translation of the bound mRNA, either by restricting it t

Barn och unga är en mycket utsatt grupp individer för vilka samhället har ett särskilt ansvar att ge stöd och skydd. Utgångspunkten är att sådant stöd ges i frivilliga former, men under vissa förutsättningar kan detta ske tvångsvis med stöd av lagen (1990:52) med särskilda bestämmelser om vård av unga. Enligt lagens 3 § kan ett tvångsingripande aktualiseras då den unge utsätter sin hälsa eller utChildren and young people constitute an especially vulnerable group of individuals to whom society has a particular responsibility to provide support and protection. The basic idea for the social welfare in Sweden is that such support is given on a voluntary basis. However under certain conditions forced interventions against the individual has been considered a necessary way of action. The means

A fire barriers are widely used in the industry as a passive fire protection system. Fire barriers are built according to specifications from manufacturer after the construction was tested in full scale furnace in accordance to the appropriate codes. Those tests are made private and the test results are not published apart from the failure/success of the tested sample. In order to accurately prote

The current healthcare system in Sweden suffers from major problems when it comes cost-efficiency and delivery of healthcare services. Unsustainable increase in healthcare cost over the past few decades has led to that Government funding is no longer keeping pace with increasing demand and complexity. There a several ways to address this issue, one is to implement a new healthcare delivery model w

Sexuella övergrepp är den vanligaste formen av skadlig behandling av barn globalt sett. Samhällets syn på barnet som ett högst skyddsvärt objekt har lett till utvecklingen av särskilda metoder för arbetet med barn idag. För att undvika risken att ett barn som varit med om en traumatisk upplevelse tvingas påminnas om det har en praxis skapats som innebär att barnet inte närvarar i rättegången. StörSexual abuse is the most common form of harmful treatment of children globally. Society´s view of the child as particularly worthy of protection has led to the development of specific methods used in the work with children today. In order to avoid the risk of children subject to abuse being forced to relive the events, a custom of not having the child attend the trial has formed. A greater focus i