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Background: Although the COVID-19 pandemic is affecting a relatively small proportion of the global population, its effects have already reached everyone. The pandemic has the potential to differentially disadvantage chronically ill patients, including those with Parkinson's disease (PD). The first health care reaction has been to limit access to clinics and neurology wards to preserve fragile pat

The majority of municipal Wastewater Treatment Plants (WWTPs) in Sweden produce biogas from sewage sludge. In order to increase the methane production, co-digestion of internal sludge with Organic Fraction of Municipal Solid Waste (OFMSW) might be feasible in the future. The objective of this study was therefore to find a beneficial solution for the utilization of OFMSW at the WWTP in Varberg, Swe

Cognitive side-effects such as emergence agitation (EA), postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are not infrequently complicating the postoperative care especially in elderly and fragile patients.The aim of the present survey was to gain insight regarding concern and interest in prevention and treatment strategies for postoperative delirium and dysfunction, and

Background Rectal bleeding is considered an alarm symptom for colorectal cancer (CRC) but it is common and mostly caused by benign conditions. Qualitative faecal immunochemical tests (FITs) for occult blood have been used as diagnostic aids for many years in Sweden when CRC is suspected. The study aimed to evaluate the usefulness of FITs requested by primary care physicians for patients with and w

Epidemiology studies suggested that low birthweight was associated with a higher risk of hypertension in later life. However, little is known about the causality of such associations. In our study, we evaluated the causal association of low birthweight with adulthood hypertension following a standard analytic protocol using the study-level data of 183,433 participants from 60 studies (CHARGE-BIG c

Advances in curative treatment to remove the primary tumor have increased survival of localized cancers for most solid tumor types, yet cancers that have spread are typically incurable and account for >90% of cancer-related deaths. Metastatic disease remains incurable because, somehow, tumors evolve resistance to all known compounds, including therapies. In all of these incurable patients, de novo

Efficient microbial sampling from surfaces for subsequent detection and quantification is crucial in fields such as food safety and hygiene monitoring. Cotton swabs are traditionally used for sample collection, but today there are numerous swabs of alternative material and different sizes available. Recovery efficiencies of swabs for different applications have been compared in several studies. Ho

Limitations in efficacy and/or tolerance of currently available urate-lowering therapies (ULTs), such as oral xanthine oxidase inhibitors, uricosurics, and intravenous uricase agents contribute to the development of refractory gout. Renal excretion is the major route of uric acid elimination, but the intestinal tract plays an increasingly recognized role in urate homeostasis, particularly in chron

A Lagrangian model of photochemistry and mixing is described (CiTTyCAT,stemming from the Cambridge Tropospheric Trajectory model of Chemistry AndTransport), which is suitable for transport and chemistry studies throughoutthe troposphere. Over the last five years, the model has been developed inparallel at several different institutions and here those developments havebeen incorporated into one "co

Background: The Swedish National Airway Register (SNAR) was initiated in 2013 to ensure and improve the quality of care for patients with asthma and COPD. Aim: To describe the development and design of SNAR, and to study the 2019 data to evaluate its potential utility related to improvement of quality of care. Methods: SNAR includes data from patients with asthma (both children and adults) and COP

The reconstruction of droughts is essential for the understanding of past drought dynamics and can help evaluate future drought scenarios in a changing climate. This article presents a reconstruction of summer droughts in France based on annually resolved, absolutely dated chronologies of oxygen isotope ratios (δ18O) in tree ring cellulose from Quercus spp. Samples were taken from living trees and

Recently we reported a method for estimating the spontaneous curvatures of lipids from temperature-dependent changes in the lattice parameter of inverse hexagonal liquid crystal phases of binary lipid mixtures. This method makes use of 1,2-dioleoyl-sn-glycerol-3-phosphoethanolamine (DOPE) as a host lipid, which preferentially forms an inverse hexagonal phase to which a guest lipid of unknown spont

Post-translational modifications (PTMs) of histones including acetylation, methylation, and ubiquitination are known to be involved in the epigenetic regulation of gene expression and thus can have an important role in tumorigenesis. A number of PTMs have been linked to pancreatic cancer and are frequently studied as potential targets for cancer therapy or diagnosis. The availability of biobank-st

We assessed the relationship between phosphocreatine (PCr) and creatine (Cr) content and creatine kinase (CK) activity in skeletal muscle of mice. The PCr and total Cr (tCr) concentrations, as well as CK activity, in hindlimb muscles of mice, with or without the cytosolic and mitochondrial isoforms of muscle creatine kinase (wild-type or CK--/-- mice), were determined by in vivo magnetic resonance

Regime shifts in lake ecosystems can occur in response to both abrupt and continuous climate change, and the imprints they leave in paleolimnological records allow us to investigate and better understand patterns and processes governing ecological changes on geological time scales. This synthesis investigates paleolimnological records that display apparent regime shifts and characterizes the shift

Introduction: Several thrombin-generation tests are available, but few have been directly compared. Our primary aim was to investigate the correlation of two thrombin generation tests, thrombin generation assay-calibrated automated thrombogram (TGA-CAT) and INNOVANCE ETP, to factor VIII levels (FVIII:C) in a group of patients with hemophilia A. The secondary aim was to investigate inter-laboratory

Despite the fact that control programs have been available for several decades, mastitis remains an important problem in dairy herds around the world. Possible reasons for this include poor uptake and application of recommended mastitis control measures; poor or variable compliance; or variability in the effects of these measures. The objective of this study was to evaluate the associations betwee

The Tropical Rainfall Measuring Mission (TRMM) Multisatellite Precipitation Analysis (TMPA) has provided a valuable precipitation dataset for hydrometeorological studies (1998–2015).However, TMPA shows some differences when compared to the ground-based estimates. In this study, a correction model is developed to improve the accuracy of the TRMM precipitation monthly product by reducing the bias co

En katalysator är en substans som kan snabba på en kemisk reaktion utan attsjälv förbrukas. Katalysatorer används vanligen i kemisk produktion och i bilarsförbränningsmotorer (för att ta bort tex CO och NO). För att optimera katalysatornoch utveckla andra och bättre katalysatorer i framtiden så behöver vi vetahur katalysatorn fungerar på atomär nivå. Katalysatorer i industrin är komplexavilket görA catalyst is a substance that can speed up the rate of a chemical reaction without itself being consumed. Catalysts are crucial for chemical production industries, where about 90% of all chemicals are produced using catalysts. They are also used for exhaust gas cleaning, for instance in cars, where CO and unburned fuels are oxidized to CO2 and NOx is reduced to N2. To optimize catalysts, and deve