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BACKGROUND: This systematic review aims to determine the loads of anti-A and anti-B in plasma-containing blood products that can safely be transfused to adults.MATERIALS AND METHODS: A comprehensive literature search was performed in PubMed, including studies dating back to 1940 until January 1 st, 2023. In total 1,869 articles were screened, describing 86 cases of hemolytic transfusion reactions

Aim of the review: This review aimed to evaluate the impact of Point-of-care Ultrasound during cardio- pulmonary resuscitation for adult non-traumatic CA on clinical outcomes and survival.Data sources: This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The PubMed and Embase databases were searched on 14 November 2022. The

Background: This study aimed to assess chlamydia diagnostics in different clinic types, including internet-based self-sampling (IBSS). Furthermore, we investigated the incidence of chlamydia-associated complications. Methods: Data on Chlamydia trachomatis (CT) testing were retrieved from six healthcare regions in the years 2016–2023 across different categories of testing facilities. National data

Bakgrund: Ett mått på följsamhet till paleolitisk kost som inte baseras på populationsrelativa intag av livsmedelsgrupper har hittills saknats. Syftet med denna avhandling var att utvärdera användbarheten av Paleolithic Diet Fraction (PDF), ett nytt mått på följsamhet till paleolitisk kost, beräknat som andelen av det totala intaget av livsmedelsgrupper som utgörs av paleolitiska livsmedelsgrupperAbstract: Background: A measure of adherence to the Paleolithic diet not based on population-relative food group intakes was lacking. The aim of this thesis was to evaluate the usefulness of the Paleolithic Diet Fraction (PDF), a novel measure of adherence to the Paleolithic diet, calculated as the fraction of total food group intake derived from Paleolithic food groups. Methods: PDF was calculate

Denna uppsats utreder huruvida rättsläget för den allmänna principen om att reklamera vid avtalsbrott utanför det lagreglerade området har förändrats till följd av Högsta domstolens avgörande i NJA 2025 s. 374 ”Brf Ida”. För att klargöra vad reklamation är konstateras att preskription har en förutbestämd tidsram, medan reklamationsfristens start- och slutpunkt varierar bero-ende på de enskilda omsThis thesis examines whether the legal situation for the general principle regarding the duty to give notice of breach of contract outside the scope of legislation has shifted due to the Supreme Court’s decision in NJA 2025 s. 374 “Brf Ida”. To clarify what the general principle of a duty to give notice is, it is noted that prescription has a fixed starting point. By contrast, the duty to give not

ALICE is a large experiment at the CERN Large Hadron Collider. Located 52 meters underground, its detectors are suitable to measure muons produced by cosmic-ray interactions in the atmosphere. In this paper, the studies of the cosmic muons registered by ALICE during Run 2 (2015–2018) are described. The analysis is limited to multimuon events defined as events with more than four detected muons (Nµ

Tau accumulation starts during the preclinical phase of Alzheimer's disease and is closely associated with cognitive decline. For preventive purposes, it is important to identify factors associated with tau accumulation and spread. Studying genetically identical twin-pairs may give insight into genetic and environmental contributions to tau pathology, as similarities in identical twin-pairs largel

Rationale: The management of indeterminate pulmonary nodules (IPNs) remains challenging, resulting in invasive procedures and delays in diagnosis and treatment. Strategies to decrease the rate of unnecessary invasive procedures and optimize surveillance regimens are needed. Objectives: To develop and validate a deep learning method to improve the management of IPNs. Methods:ALung Cancer Prediction

Objective: Huntington's disease (HD) is an inherited neurodegenerative disease with motor, cognitive and psychiatric symptoms. Non-motor symptoms like depression and altered social cognition are proposed to be caused by dysfunction of the hypothalamus. We measured the hypothalamic neuropeptide oxytocin in plasma and cerebrospinal fluid (CSF) in a cohort of HD gene expansion carriers (HDGECs), comp

Within the next 30 years, two thirds of the human population will live in a city. This growing urban population requires a major shift in the way we produce and distribute food, since conventional agriculture practices are responsible for climate change, biodiversity losses, pollution of waterways, soil degradation, etc. Urban and peri-urban agriculture and forestry represent one of the strategies

Aims: Little is known how insulin secretion and action change over time in populations of different ethnicities. We studied changes in insulin secretion and action with increasing age in Iraqi-born immigrants and native Swedes, and investigated if the changes were modified by region of origin.Methods: Residents of Malmö, 30-75 years of age born in Iraq or Sweden, were invited to participate in thi

BACKGROUND: Asthma is characterised by an aggravated immune response to respiratory viral infections. This phenomenon is a clinically well-recognised driver of acute exacerbations, but how different phenotypes of asthma respond immunologically to viruses is unclear. OBJECTIVES: To describe the association between different phenotypes and severity of asthma and bronchial epithelial immune responses

BackgroundDiabetes and prediabetes are well-recognized risk factors for cardiovascular disease (CVD) and are marked by vascular endothelial dysfunction (ED). However, there is a scarcity of thorough population-based studies examining ED in individuals with diabetes/prediabetes free from manifest CVD. Here, we examined the association between ED assessed by reactive hyperaemia index (RHI) in the fi

Introduction: Primary human papilloma virus (HPV) screening to detect cervical cancer and dysplastic lesions was implemented in Region Skåne 2017 for women aged 30–70. The aim of this study was to characterize the screening history of women diagnosed with cervical cancer to evaluate the performance of the screening program, as well as to assess the cancer treatments given and shortcomings in the f

The moth, Spodoptera littoralis, was demonstrated to be a new model system for studying mechanisms underlying odour conditioning. In the experiments a restrained moth was trained to learn an association between a conditioned stimulus (CS) and an unconditioned stimulus (US). A proboscis extension reflex (PER) elicited by the conditioned odour was observed after learning. In paper I, an odour-sucros

INTRODUCTION.: The most common immunosuppressive treatment in de novo renal transplantation is a triple regimen that includes tacrolimus, mycophenolate mofetil (MMF) and corticosteroids, and that may also include antibody induction. Whether nephrotoxicity is an issue with tacrolimus at the currently used dosages remains an open question. METHODS.: We pooled data from three large, randomized, de no

Background. To validate a test for independent assessment of insulin secretion and insulin sensitivity during the same occasion for metabolic studies in clinical practice, i.e. combined glucagon-stimulated C-peptide test and insulin tolerance test (GITT). Subjects and methods. We measured C-peptide response to 0.5 mg of intravenous glucagon followed 30 min later by administration of 0.05 U kg(-1)

ABSTRACT: BACKGROUND: Negative pressure wound therapy (NPWT) is believed to initiate granulation tissue formation via macro-deformation of the wound edge. However, only few studies have been performed to evaluate this hypothesis. The present study was performed to investigate the effects of NPWT on wound contraction and wound edge tissue deformation. METHODS: Six pigs underwent median sternotomy f

BACKGROUND: Women with a breast cancer susceptibility gene 1 (BRCA1) or breast cancer susceptibility gene 2 (BRCA2) mutation are at increased risk for developing breast and ovarian cancer. Various reproductive and hormonal factors have been shown to modify the risk of breast cancer. These studies suggest that estrogen exposure and deprivation are important in the etiology of hereditary cancer. Man