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OBJECTIVE: To describe the distribution of HIV-1 variants in population-based national surveys conducted in sub-Saharan African countries between 2015 and 2022.DESIGN: Multicountry analysis.METHODS: Sixteen population-based national surveys, conducted between 2015 and 2022, were analyzed. Survey participants were eligible if HIV genotyping was successful. In most countries, people with HIV (PWH) w
Large cardiac rhabdomyomas can disturb hemodynamic flow. Tuberous sclerosis complex is the most common cause of cardiac rhabdomyoma in fetuses. Recently, a mammalian target of rapamycin (mTOR) inhibitor effectively treated rhabdomyomas associated with tuberous sclerosis. Here, we report the effectiveness of an mTOR inhibitor in treating a fetus with large rhabdomyomas exhibiting severe heart failu
För att minska och försöka eliminera utsläppen av koldioxid från byggsektorn krävs alternativ till dagens metod att skapa önskad funktion genom att riva befintliga byggnader följt av nyproduktion. Nyproduktion av byggnader medför stora klimatbelastande utsläpp kopplade till framställning av nya produkter och material, men även kopplat till rivnings- och nybyggnadsprocessen. Samtidigt är en del av Decarbonisation of the built environment requires alternatives to the prevailing practice of demolition followed by new construction. The new production of buildings adds upfront embodied emissions, while much of the non-residential stock remains underutilised, and housing demand remains high. Adaptive reuse, the practice of converting existing buildings for new functions, preserves the building's
Background: Current guidelines for the treatment of severe TBI recommend maintaining a cerebral perfusion pressure (CPP) at 60–70 mmHg. In our institution, as well as others, an alternative algorithm—originally named the Lund concept—has been used. This treatment algorithm employs metoprolol and clonidine to limit CPP, accepting levels below 60 mmHg, with the aim of reducing cerebral edema. Previo
Examensarbetets titel: Kun(d)skapsintensivt arbete - Ledarskap och motivation i en kundnära kunskapsintensiv organisation Seminariedatum: 15 januari 2026 Kurs: FEKH49 - Examensarbete i organisation på kandidatnivå, 15 högskolepoäng Författare: Filippa Kapoor Åberg och Sakarias Moberg Handledare: Stefan Sveningsson Fem nyckelord: Kunskapsintensiv verksamhet, kundstyrning, ledarskap, motivation, psyTitle: Knowledge(client) intensive work - Leadership and Motivation in a client-centered knowledge-intensive firm Seminar Date: 15th January 2026 Course: FEKH49 - Bachelor’s degree thesis in Management and Organization, 15 credits. Authors: Filippa Kapoor Åberg and Sakarias Moberg Supervisor: Stefan Sveningsson Five Keywords: Knowledge-intensive firms, Client control, leadership, motivation, psych
OBJECTIVE: Investigate the relationship between changes in lower limb EMG root mean square (RMS) activity and changes in body movement during perturbed standing. Specifically, linear movement variance, torque variance and body posture were correlated against tibialis anterior and gastrocnemius RMS EMG activity during perturbed standing by vibration of the calf muscles. METHODS: Eighteen healthy pa
Context: Dopamine agonists are the treatment of choice for prolactinomas and symptomatic idiopathic hyperprolactinemia. However, the optimal treatment strategy and treatment duration is not clear in all details. Objective: The aim of the study was to assess the effect of dopamine agonist withdrawal in patients with idiopathic hyperprolactinemia and prolactinomas. Data Sources: PubMed, the Cochrane
OBJECTIVES: The aim of this study was to investigate whether job strain, psychological demands, and decision latitude are independent determinants of disability pension rates over a 12-year follow-up period. METHODS: We studied 3,181 men and 3,359 women, all middle-aged and working at least 30 h per week, recruited from the general population of Malmö, Sweden, in 1992. The participation rate was
Purpose: To compare the effects of ageing and glaucoma progression on the thickness of the circumpapillary retinal nerve fibre layer (cpRNFL) and to evaluate the performance of a set of optical coherence tomography (OCT) progression analyses. Methods: The cpRNFL was measured twice by OCT at each of two visits made 10 years apart in 69 healthy individuals and 49 glaucoma patients. Both visits also
Biochar has been extensively studied as a soil amendment for carbon sequestration and for improving soil quality; however, a systematic understanding of the responses of soil microbial biomass and diversity to biochar addition is lacking. Here, a meta-analysis of 999 paired data points from 194 studies shows that biochar increases microbial biomass but has variable effects on microbial diversity.
BackgroundElbow strength ratios in relation to performance level, in male and female climbers, are scarcely documented. The aim of this study was to investigate elbow muscle strength, strength ratio and hand grip strength in climbers and its potential relationship to performance level.HypothesisWe hypothesized that there is a relationship between performance level and various strength variables an
Cardiac arrest effectiveness trials have traditionally reported outcomes that focus on survival. A lack of consistency in outcome reporting between trials limits the opportunities to pool results for meta-analysis. The COSCA initiative (Core Outcome Set for Cardiac Arrest), a partnership between patients, their partners, clinicians, research scientists, and the International Liaison Committee on R
Cardiac arrest effectiveness trials have traditionally reported outcomes that focus on survival. A lack of consistency in outcome reporting between trials limits the opportunities to pool results for meta-analysis. The COSCA initiative (Core Outcome Set for Cardiac Arrest), a partnership between patients, their partners, clinicians, research scientists, and the International Liaison Committee on R
INTRODUCTION: The optimal bowel preparation strategy to minimise the risk of anastomotic leak is yet to be determined. This study aimed to determine whether oral antibiotics combined with mechanical bowel preparation (MBP+Abx) was associated with a reduced risk of anastomotic leak when compared to mechanical bowel preparation alone (MBP) or no bowel preparation (NBP).METHODS: A pre-planned analysi
Background Cutaneous leishmaniasis (CL) is frequent in travellers and can involve oro-nasal mucosae. Clinical presentation impacts therapeutic management. Methodology Demographic and clinical data from 459 travellers infected in 47 different countries were collected by members of the European LeishMan consortium. The infecting Leishmania species was identified in 198 patients. Principal findings C
Background: Neuropeptides, such as substance P (SP), have long been seen as mediators of widespread continuous airway inflammation, a process known as neurogenic inflammation. However, this has been difficult to demonstrate clinically, suggesting an alternative role for these signaling molecules. Objectives: We sought to examine the role of SP in nasal infection by assessing the release of SP in r
Investigation of contaminant sources is indispensable for developing effective countermeasures against nitrate (NO3 −) pollution in groundwater. Known major nitrogen (N) sources are chemical fertilizers, livestock waste, and domestic wastewater. In general, scatter diagrams of δ18O and δ15N from NO3 − can be used to identify these pollution sources. However, this method can be difficult to use for
The aim of this study was to identify molecules that trigger complement activation in rheumatic joints. C4d, the final cleavage product of C4 activation, is found in the diseased joint and can bind covalently to complement-activating molecules. By using a highly specific Ab against a cleavage neoepitope in C4d, several molecules that were specifically bound to C4d were identified from pooled synov
Reactive oxygen species (ROS) are important contributors to the secondary injury cascade following traumatic brain injury (TBI), and ROS inhibition has consistently been shown to be neuroprotective following experimental TBI. NXY-059, a nitrone free radical trapping compound, has been shown to be neuroprotective in models of ischemic stroke but has not been evaluated in experimental TBI. In the pr
