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Postal address Pufendorf I.A.S., Lund University, Box 117, 221 20 Lund Visiting address Biskopsgatan 3, Lund Website www.pi.lu.se 1 Lund, September 2017 Pufendorf Institute for Advanced Studies Call for proposals to form a ”theme” at the Pufendorf Institute 2018 The Pufendorf IAS invites researchers to apply for a “theme” to start in the autumn of 2018. Provided that sufficient funding is granted,

https://www.pi.lu.se/sites/pi.lu.se/files/utlysning_teman_2018-19_eng.pdf - 2026-06-25

Objective: To examine the possible relationships of breast cancer risk to prediagnostic plasma levels of insulin; insulin-like growth factor-I (IGF-I); and IGF-binding proteins -1, -2, and -3. Methods: Within two prospective cohorts in Umea and Malmo we measured plasma concentrations of insulin, IGF-I, and IGFBPs for a total of 513 incident breast cancer cases and 987 matched controls. Results: Gl

Preference studies of many different collembolan species have categorised collembolans being selective in their food choice. To clarify whether collembolan food selectivity is related to fitness parameters, three species, Folsomia fimetaria, Protaphorura armata and Heteromurus nitidus, were fed three fungal species, Alternaria infectoria, Mucor hiemalis and Penicillium hordei, representing fungi o

During forward flight, a bird's body generates drag that tends to decelerate its speed. By flapping its wings, or by converting potential energy into work if gliding, the bird produces both lift and thrust to balance the pull of gravity and drag. In flight mechanics, a dimensionless number, the body drag coefficient (C-D,C-par), describes the magnitude of the drag caused by the body. The drag coef

Macroalgae cultivation shows potential for the application as emerging feedstock for microbial fermentation to produce biochemicals. However, metal residues in macroalgae might affect the fermentation capacity of relevant microorganisms. This aspect is currently not considered when selecting macroalgae and microorganism species for microbial fermentation. To consider this aspect for selecting viab

It is of paramount importance that software reliability requirements not only can be formulated, but also enforced and evaluated before accepting a software product for release. This requires sound acceptance criteria for software, which implies that methods for evaluating the software reliability are needed during the testing phase. Thus, theoretical models which are practically applicable are ne

This study evaluates the potential of supervised and transfer learning techniques to assist energy system optimization. A surrogate model is developed with the support of a supervised learning technique (by using artificial neural network) in order to bypass computationally intensive Actual Engineering Model (AEM). Eight different neural network architectures are considered in the process of devel

This study examines the interdependence between research and development (R&D) resources, coopetitive performance, and extent of cooperation in development-related standardization settings that involve network effects. Coopetitive performance is measured as the firm’s influence on the change process of standards. Cooperation is measured as the number of firm technology partners in influencing

The historical evolution of languages has been more than once influenced by the sheer influence of scholars who re-channeled some linguistic phenomena or simply consecrated aspects of colloquial usage. This happened in the history of Romanian language when the Latinist scholars cleansed the lexicon and parts of morphology of various non-Latin borrowings and derivations whereas they revived or inse

Microbial substrate use efficiency is an important property in process-based soil organic matter models, but is often assumed to be constant in mechanistic models. However, previous studies question if a constant efficiency is appropriate, in particular when evaluating carbon (C) cycling across temperatures and various substrates. In the present study, we evaluated the relation between substrate u

People who live in brown bear areas often fear encounters with these animals. This article evaluated the potential effect of exposure to bears and their habitats on human fear of brown bears using the modeling of appropriate behavior when close to bears. In a within-subject design, 25 persons who reported to be fearful of brown bears participated in a guided walk approaching approximately 50 m of

När konsumenter köper en produkt så har de förväntningar på vad produkten kommer att kunna leverera. Rationella argument försöker försäkra sig om att produktens tekniska egenskaper kommer att bli till belåtenhet. Men det är ändå ofta känslan som får sista ordet. Känns produkten rätt, tillräckligt attraktiv, eller är den ens värd att betala så mycket för? Det är väl känt att människans perception iWhen consumers buy a new product, they have expectations about what that product will deliver. The consumer’s rational reasoning may try to ascertain whether the technical performance of the product will be fulfilled. Nevertheless, the final word is often subjective. Does it feel right? Is the product attractive, is it worth paying that much for? It is well established that human perception is hig

The Natura 2000 network of protected sites is one of the means to enable biodiversity conservation in Europe. EU member states have to undertake surveillance of habitats and species of community interest protected under the Habitat Directive. Remote sensing techniques have been applied successfully to monitor biodiversity aspects according to Natura 2000, but many challenges remain in assessing dy

Background:Nurses and physicians in nephrology settings provide care for patients with end-stage kidney disease receiving hemodialysis treatment along a complex illness trajectory.Aim:The aim was to explore physicians’ and nurses’ perspectives on the trajectories toward the end of life involving decisions regarding hemodialysis withdrawal for patients with end-stage kidney disease.Research design

The incorporation of a free fatty acid into the sn-1 position of phosphatidylcholine by lipase-catalyzed transesterification was investigated. The thermodynamic water activity of both the enzyme preparation and the substrate solution was adjusted to the same value prior to the reaction. The reaction rate increased with increasing water activity but the yield of modified phosphatidylcholine decreas

The aim of this study was to determine the association between childhood insulin-dependent diabetes mellitus (IDDM) and HLA-DR4 subtypes and to test in a population-based investigation whether the DR4 association has an effect independent to that of DQ. First, HLA genotyping identified DR4 in 337/425 (79%) patients and 148/367 (40%) controls (Odds Ratio 5.67; p < 0.01). Second, a total of 14 DR4 s

Multigene expression signatures provide a molecular subdivision of early breast cancer associated with patient outcome. A gap remains in the validation of such signatures in clinical treatment groups of patients within population-based cohorts of unselected primary breast cancer representing contemporary disease stages and current treatments. A cohort of 3520 resectable breast cancers with RNA seq

BACKGROUND: Vasopressin is widely used for vasopressor support in septic shock patients, but experimental evidence suggests that selective V1A agonists are superior. The initial pharmacodynamic effects, pharmacokinetics, and safety of selepressin, a novel V1A-selective vasopressin analogue, was examined in a phase IIa trial in septic shock patients.METHODS: This was a randomized, double-blind, pla

Vertebral augmentation is among the current standards of care to reduce pain in patients with vertebral fractures (VF), yet a lack of consensus regarding efficacy and safety of percutaneous vertebroplasty and kyphoplasty raises questions on what basis clinicians should choose one therapy over another. Given the lack of consensus in the field, the American Society for Bone and Mineral Research (ASB