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2019–2022 A prize worth SEK 1 million for outstanding and ground-breaking research, and a full day dedicated to popular science and interdisciplinary lectures in economics and management 2019–2022 – this was the result of a generous donation from the Jan and Åsa Söderberg family to the Lund University School of Economics and Management. The Jan Söderberg Family Prize in Economics and Management wa
Although quality of life has been in the focus of attention for over a decade there are few studies available investigating, how the old and the oldest old experience their quality of life or what quality of life actually means for them? To illuminate this, eleven in-depth interviews were conducted with six women and five men (80+) living in their home. An interpretative hermeneutic phenomenologic
Transposable Elements: A Common Feature of Neurodevelopmental and Neurodegenerative Disorders Trends in Genetics TIGS 1671 No. of Pages 14 Review Transposable Elements: A Common Feature of Neurodevelopmental and Neurodegenerative Disorders Marie E. Jönsson,1,3 Raquel Garza,1,3 Pia A. Johansson,1,3 and Johan Jakobsson1,2,*,@ Highlights Transposable elements (TEs) make up almost half of our genome b
Consistent datasets of the laminar burning velocity, LBV, for homologous fuels are indispensable for the elucidation of the structure-reactivity trends and the development and validation of pertinent detailed kinetic models. In the present study, all available LBV measurements for small alkyl esters obtained using the heat flux method have been reviewed. New results of the LBV for methyl propionat
With ongoing climate change, aridity is increasing worldwide, affecting biodiversity and ecosystem function in drylands. However, how the depth-profile microbial community structure and metabolic limitations change along aridity gradients are still poorly explored. Here, 16S rRNA and ITS amplicon sequencing and ecoenzymatic stoichiometry analysis were used to investigate both bacterial and fungal
Background and Purpose: Target delineation in glioblastoma is still a matter of extensive research and debate. This guideline aims to update the existing joint European consensus on delineation of the clinical target volume (CTV) in adult glioblastoma patients. Material and Methods: The ESTRO Guidelines Committee identified 14 European experts in close interaction with the ESTRO clinical committee
Objective Longitudinal clinical registry-infrastructures such as Anti-Rheumatic Therapies in Sweden (ARTIS) allow simultaneous comparison of the safety of individual immunomodulatory drugs used in clinical practice, with consistent definitions of treatment cohorts, follow-up and outcomes. Our objective was to assess and compare incidence rates of key safety outcomes for individual targeted synthet
Part II of the European clinical guidelines for Tourette syndrome and other tic disorders (ECAP journal, 2011) provides updated information and recommendations for psychological interventions for individuals with tic disorders, created by a working group of the European Society for the Study of Tourette Syndrome (ESSTS). A systematic literature search was conducted to obtain original studies of ps
Objective Behaviour therapy (BT) for Tourette's disorder (TD) and persistent (chronic) motor or vocal tic disorder (PTD) is rarely available. We evaluated the feasibility of adapting two existing BT protocols for TD/PTD (habit reversal training (HRT) and exposure and response prevention (ERP)) into a therapist-guided and parent-guided online self-help format. Design A pilot, single-blind, parallel
Urban freight logistics is a growing phenomenon in cities and contributes to the wealth of citizens and businesses in urban areas. But it also has negative side effects such as emissions, congestion, and accidents, which eradicate some of their benefits for society. The current development of urban freight logistic activities is unsustainable. A more sustainable path of development is needed but i
Background: Reliable biomarkers of androgen activity in humans are lacking. The aim of this study was, therefore, to identify new protein markers of biological androgen activity and test their predictive value in relation to low vs normal testosterone values and some androgen deficiency linked pathologies. Methods: Blood samples from 30 healthy GnRH antagonist treated males were collected at three
Prognosis after myocardial infarction (MI) varies greatly depending on the extent of dam-aged area and the management of biological processes during recovery. Reportedly, the inhibition of the pro‐inflammatory S100A9 reduces myocardial damage after MI. We hypothesize that a S100A9 blockade induces changes of major signaling pathways implicated in post‐MI healing. Mass spectrometry‐based proteomics
BackgroundThe etiology of male breast cancer (MBC) is poorly understood. In particular, the extent to which the genetic basis of MBC differs from female breast cancer (FBC) is unknown. A previous genome-wide association study of MBC identified 2 predisposition loci for the disease, both of which were also associated with risk of FBC.MethodsWe performed genome-wide single nucleotide polymorphism ge
This dissertation analyzes and evaluates several major productions by Danish philosopher and theologian Søren Kierkegaard (1813–1855). It focuses on three works Kierkegaard authored under pseudonyms – Either / Or (1843), Fear and Trembling (1843), and Philosophical Fragments (1844) – and the non-pseudonymously authored Works of Love (1847). The dissertation argues that for Kierkegaard, Christian f
Wound infection is a common and serious medical condition with an unmet need for improved diagnostic tools. A peptidomic approach, aided by mass spectrometry and bioinformatics, could provide novel means of identifying new peptide biomarkers for wound healing and infection assessment. Wound fluid is suitable for peptidomic analysis since it is both intimately tied to the wound environment and is r
PURPOSE: Diffusion-weighted MRI is sensitive to incoherent tissue motion, which may confound the measured signal and subsequent analysis. We propose a "motion-compensated" gradient waveform design for tensor-valued diffusion encoding that negates the effects bulk motion and incoherent motion in the ballistic regime.METHODS: Motion compensation was achieved by constraining the magnitude of gradient
Thyroid cancer (TC) is substantially more common in women than in men, pointing to a possible role of sex steroid hormones. We investigated the association between circulating sex steroid hormones, sex hormone binding globulin (SHBG) and the risk of differentiated TC in men and women within the European Prospective Investigation into Cancer and nutrition (EPIC) cohort. During follow-up, we identif
The purpose of this review was to analyze the scientific literature on exocrine pancreatic insufficiency (EPI) in dogs and cats and our own research on porcine model to compare animal- and microbial-derived enzymes in the treatment of animals with this disease. Clinical signs of EPI occur when more than 85% of the pancreatic parenchyma is non-functional. EPI can be a consequence of various disease
Enhancing forest drought resilience is important for preserving ecosystem services in the face of climate change, but operational management methods for boreal forests aiming to preserve ecosystem services under drought are still largely missing. This study explores the use of satellite remote sensing to monitor vegetation stress phases related to drought progression and to quantify both short- an
Objective: Individuals with psychiatric illness suffer from poorer physical health compared with the general population and have a higher risk of developing cardiovascular and metabolic diseases. This cross-sectional study aims to describe the prevalence of lifestyle and cardiovascular risk factors and the association with self-reported psychiatric symptoms in a population of 40-year-old individua
