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PURPOSE: To investigate the incidence and causes of visual impairment in children born prematurely in Finland from 1972 through 1989, and to determine what conditions and factors were associated with its occurrence. DESIGN: Retrospective, cross-sectional study. SUBJECTS: All visually impaired individuals from 0 to 17 years of age who had been born at fewer than 37 gestational weeks in Finland from
Eddy covariance (EC) measurements are often used to validate net ecosystem productivity (NEP) estimated from satellite remote sensing data and biogeochemical models. However, EC measurements represent an integrated flux over their footprint area, which usually differs from respective model grids or remote sensing pixels. Quantifying the uncertainties of scale mismatch associated with gridded flux
Background To benefit from the increasing clinical evidence, organisational changes have been among the main drivers behind the reduction of ICU mortality during the last decade. Increasing demand, costs and complexity, amplifies the need for optimisation of clinical processes and resource utilisation. Thus, multidisciplinary teamwork and critical care processes needs to be adapted to profit from
OBJECTIVES: To characterise autoimmune congenital heart block (CHB) associated with a maternal diagnosis of primary Sjögren's syndrome (pSS) confirmed either before, concomitant or after the first pregnancy complicated with CHB.METHODS: The following inclusion criteria were applied: (i) Mothers with positive Ro/La autoantibodies detected previously or at the time of diagnosis of the first case of
Precipitation is a major component of the water cycle. Accurate and reliable estimation of precipitation is essential for various applications. Generally, there are three main types of precipitation products: satellite based, reanalysis, and ground measurements from rain gauge stations. Each type has its advantages and disadvantages. Recent efforts have been made to develop various merging methods
Background Human trafficking is considered a hidden global crime with unsubstantiated numbers. Despite the challenges in counting or measuring this crime, reports revealed the presence of around 40.3 million victims worldwide. Human trafficking results in severe detrimental impacts on both mental and physical health. Given the sensitivity and negative consequences of human trafficking on the globa
Importance: Phase 3 trials of successful antiamyloid therapies in Alzheimer disease (AD) have demonstrated improved clinical efficacy in people with less severe disease. Plasma biomarkers will be essential for efficient screening of participants in future primary prevention clinical trials testing antiamyloid therapies in cognitively unimpaired (CU) individuals with initially low brain β-amyloid (
Background: Various factors modulate circulating testosterone in men, affecting interpretation of testosterone measurements. Purpose: To clarify factors associated with variations in sex hormone concentrations. Data Sources: Systematic literature searches (to July 2019). Study Selection: Prospective cohort studies of community-dwelling men with total testosterone measured using mass spectrometry.
Background: Hypertension is the leading risk factor for cerebral small vessel disease. We aimed to determine whether antihypertensive drug classes differentially affect microvascular function in people with small vessel disease. Methods: We did a multicentre, open-label, randomised crossover trial with blinded endpoint assessment at five specialist centres in Europe. We included participants aged
Aims/hypothesis: The aim of this study was to determine whether BMI in early childhood was affected by the COVID-19 pandemic and containment measures, and whether it was associated with the risk for islet autoimmunity. Methods: Between February 2018 and May 2023, data on BMI and islet autoimmunity were collected from 1050 children enrolled in the Primary Oral Insulin Trial, aged from 4.0 months to
Sveriges regering satte 2011 upp mål om att bli bäst på att utnyttja digitaliseringens möjligheter. Digitaliseringen av bygglovsprocessen har trots det gått långsamt. Bygglovsprocessen idag (2018) är en långsam, dyr och ineffektiv process. Möjligheten att söka bygglov med e-legitimation finns endast hos 30 procent av kommunerna och 60 procent har någon slags e-tjänst ansökan. Ansökningarna innebär
The relationship between ancient hominins and modern humans, from a new perspective Many questions followed the discovery and identification of the Neanderthal from the fossil record in 1856 as to its place in the hominin tree and its relationship with modern humans. Was it a direct ancestor? A remote cousin? Or did it mix with humans? Once reliable nuclear DNA data became available in 2010, the
I svensk rätt gäller som utgångpunkt att medicinska och psykiatriska åtgärder inte får ges utan att patienten har samtyckt till dem. Undantag från denna huvudregel finns, till exempel när tvångsvård ges med stöd av lagen om psykiatrisk tvångsvård (LPT). En utgångspunkt är dock att patienter inom svensk sjukvård ges självbestämmanderätt. I vilken grad minderåriga patienter ska erkännas självbestämIn Swedish law, an important main rule is that medical and psychiatric measures cannot be given without consent from the patient. There are exceptions from this rule, f.ex. when treatment is given involuntary under the Act on Compulsory Psychiatric Care (LPT). But as a main rule, patients in Swedish health care have the right to self-determination. To which degree children shall be given the righ
Sweden faces an upcoming period where thousands of buildings built during the million program period will be in need of a façade renovation. There is a large energy-saving potential in these buildings, since they are often poorly insulated and often have a ventilation system without heat recovery. Performing energy-efficient renovation measures to a building are expensive, which results in that th
Popular science summary Non steroid anti-inflammatory drugs (NSAIDs) are among the most consumed pharmaceuticals worldwide, and thus belong to the most frequently identified pharmaceuticals in aquatic environments. Until now multiple examinations have shown adverse effects of NSAIDs on life functions of aquatic organisms even in low concentrations. However, there is still lack of data about toxic
Background Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabet
In the search for renewable vehicle fuels several different gasoline additives have been discussed and reviewed. Today bioethanol is the most commonly used option, but isobutanol is being proposed as a better alternative by many stakeholders, due to its superior fuel characteristics, e.g. energy density, oxygen content and vapor pressure. The research project “Glycerol-based isobutanol” has invest
Popular Abstract in Swedish Den globala uppvärmningen av vår jord påverkar inte bara lufttemperaturen, utan även haven blir varmare. Dessutom förespås en ökning i nederbörd vilket kommer att göra havens ytvatten mindre salta. Temperaturförändringen och den ökade nederbörden kan leda till att skiktningen, den s.k. vertikala stratifieringen, som finns naturligt i haven blir skarpare och starkare. StIncreasing precipitation and surface water temperature due to global change may strengthen stratification in coastal regions, which could influence the behavior of dinoflagellate diel vertical migration (DVM). DVM is a behavioral mechanism by which dinoflagellates can access photosynthetically active radiation near the surface, and nutrients at depth. During this process, cells may need to cross b
Importance Active perinatal care increases survival of extremely preterm infants; however, improved survival might be associated with increased disability among survivors. Objective To determine neurodevelopmental outcome in extremely preterm children at 2.5 years (corrected age). Design, Setting, and Participants Population-based prospective cohort of consecutive extremely preterm infants born be
Given electronic wave functions generated by the grasp2K relativistic atomic structure package, this program calculates diagonal magnetic dipole A(J) and electric quadrupole B-J hyperfine interaction constants and Lande g(J) factors. In addition the program computes diagonal and off-diagonal reduced hyperfine and Zeeman matrix elements and constructs the total interaction matrix for an atom in an
