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Conidiation in Penicillium cyclopium is induced by conidiogenone, an endogenous diterpene

The filamentous fungus Penicillium cyclopium conidiates in the presence of calcium ions in submerged culture without nutrient limitation according to a precisely timed program. Conidiation could be prematurely induced in a nutritionally sufficient medium which had previously supported growth, suggesting that a metabolite which influenced the process was produced. A diterpenoid with conidiation-ind

Neurodevelopmental Outcome in Extremely Preterm Infants at 2.5 Years After Active Perinatal Care in Sweden

Importance Active perinatal care increases survival of extremely preterm infants; however, improved survival might be associated with increased disability among survivors. Objective To determine neurodevelopmental outcome in extremely preterm children at 2.5 years (corrected age). Design, Setting, and Participants Population-based prospective cohort of consecutive extremely preterm infants born be

Comparing two low-energy diets for the treatment of knee osteoarthritis symptoms in obese patients: a pragmatic randomized clinical trial

Objectives To evaluate in a prospective, randomized clinical trial (RCT), symptom response among obese knee osteoarthritis (OA) patients following a feasible. intensive weight-loss program for 16 weeks Methods Eligible patients were obese [body mass index (BMI)> 30 kg/m(2)], >50 years old, with primary knee OA Participants were randomized to either a very-low-energy diet (VLED) or a low-energy die

Landlords' Experiences of Housing Tenants Suffering from Severe Mental Illness: A Swedish Empirical Study

The aim of this Swedish study was to describe landlords' experiences of having tenants suffering from severe mental illness. Sixteen landlords working in private and public housing agencies participated in open in-depth interviews. Data were subjected to a thematic latent content analysis. The results showed that having tenants with severe mental illness entails being confronted with various diffi

Coagulation disturbances in the critically ill patient with special reference to prediction of outcome

Popular Abstract in Swedish Kritiskt sjuka patienter på intensivvårdsavdelningar (IVA) har ofta störningar i blodets levringsförmåga (koagulation). Kliniska tecken som blodpropp (djup ventrombos eller blodpropp i lungorna) och/eller blödning kan vara resultatet av aktivering och konsumtion av koagulationsfaktorer och koagulationshämmare. Disseminerad intravaskulär koagulation (DIC, som är en samtiCritically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. Global haemostatic tests are inexpensive, widely available, and ma

Field-induced assembly of colloidal ellipsoids into well-defined microtubules.

Current theoretical attempts to understand the reversible formation of stable microtubules and virus shells are generally based on shape-specific building blocks or monomers, where the local curvature of the resulting structure is explicitly built-in via the monomer geometry. Here we demonstrate that even simple ellipsoidal colloids can reversibly self-assemble into regular tubular structures when

It takes two to Tango!

If you want to become “teacher of the year“ - how do you do? The easy answer is to get yourself a group of “students of the year“! But, if you don't have that – how do you help your average students to become “students of the year“? In order to do that we must be active and take pedagogical leadership. In this roundtable we want to discuss questions like: • How can we stimulate the students’ inter

Finding the way home: supporting wayfinding for older users with memory problems

Being able to orient in the vicinity of the home and independently go shopping or visiting a friend can become increasingly difficult when a person suffers from memory decline. The adaption of traditional navigation apps based on satellite positioning could provide an aid, but there are several questions to investigate related to the design and function of such an app. These questions include how

Formate dehydrogenase-modified carbon paste electrodes for amperometric detection of formate

A simple and inexpensive amperometric biosensor for formate detection was obtained by immobilization of for-mate dehydrogenase (FDH) on graphite powder, modified with a new phenothiazine derivative (DDDP; 16H, 18H-dibenzo[c,l]-7,9-dithia-16,18-diazapentacene). Two different enzyme environments were used: FDH was adsorbed on DDDP-modified graphite powder in the presence of polyethylenimine (PEI) as

Selecting antonyms for dictionary entries: methodological aspects

This paper investigates the treatment of antonymy in Collins COBUILD Advanced Learner’s English Dictionary (2003) in order to find out what kinds of headwords are provided with antonyms as part of their definitions and also discusses the principles for antonym inclusion in the entries. CCALED includes canonical antonyms such as good/bad and dead/alive, as well as more contextually restricted pairi

The association between retinopathy, nephropathy, cardiovascular disease and long-term metabolic control in type 1 diabetes mellitus: a 5 year follow-up study of 442 adult patients in routine care

The aim of the present study was to examine mean HbA1c and blood pressure levels during a 5 year period in 442 type 1 adult diabetic patients in relation to the incidence and progression of retinopathy, nephropathy and to cardiovascular morbidity and mortality. The study showed, that in patients under routine care at a diabetic unit with four visits to the out-patient clinic per year, the intraind

Visual impairment in children born prematurely from 1972 through 1989

PURPOSE: To investigate the incidence and causes of visual impairment in children born prematurely in Finland from 1972 through 1989, and to determine what conditions and factors were associated with its occurrence. DESIGN: Retrospective, cross-sectional study. SUBJECTS: All visually impaired individuals from 0 to 17 years of age who had been born at fewer than 37 gestational weeks in Finland from

Influence of added particles on the phase behavior of polymer solutions. Analysis by mean-field lattice theory

The influence of added colloidal particles on the phase stability of polymer solutions is investigated theoretically. The polymer has an affinity to the particle surface. A mean-field lattice theory based on the Flory-Huggins theory is used to calculate the phase behavior in solutions containing a single polymer component and particles. The particles are described in two different ways. The first

Covert bilingualism and symbolic competence: Analytical reflections on negotiating insider/outsider positionality in Swedish speech situations

Bilinguals often face the challenge of negotiating a range of insider/outsider subject positions when interacting in transnational and intercultural settings. This article takes up the concept of symbolic competence, the awareness of socially situated symbolic resources and the ability to use them to shape interactional contexts, to examine how the author, a Swedish–English bilingual, manages this

Immune-Related and Inflammatory Conditions and Risk of Lymphoplasmacytic Lymphoma or Waldenstrom Macroglobulinemia.

Background Chronic immune stimulation appears to be associated with lymphoplasmacytic lymphoma (LPL)-Waldenström macroglobulinemia (WM); however, available information is sparse. We conducted, to our knowledge, the most comprehensive study to date to evaluate associations between a personal or family history of many immune-related and/or inflammatory disorders and the subsequent risk of LPL-WM. Me

Tilt testing remains a valuable asset

Head-up tilt test (TT) has been used for >50 years to study heart rate/blood pressure adaptation to positional changes, to model responses to haemorrhage, to assess orthostatic hypotension, and to evaluate haemodynamic and neuroendocrine responses in congestive heart failure, autonomic dysfunction, and hypertension. During these studies, some subjects experienced syncope due to vasovagal reflex. A

Unlimiting Unlimited Liability : Legal Equality for Swedish Banks with Alternative Shareholder Liability Regimes (1897-1903)

This paper examines the aftermath of the 1897 Riksbank Act in Swedish banking. The Act placed banks with unlimited and limited liability upon equal footing, removing the note issuing privileges of the former. We consider whether changes in risk preferences occurred subsequent to the Act, or whether extended liability was a sufficient deterrent. We conclude that when legal differences were removed,

Does culture influence the implementation of Enterprise Risk Management?

The primary purpose of this study is to investigate if culture influences a firm’s decision to implement enterprise risk management (ERM). It will examine which factors influence this decision on a worldwide level, how ERM implementation varies across countries and to what extent these differences are influenced by cultural dimensions. The study is based on 380 firm observations from 19 countries.

Toxicity of the ibuprofen degradation product 4’-IBAP

Popular science summary Non steroid anti-inflammatory drugs (NSAIDs) are among the most consumed pharmaceuticals worldwide, and thus belong to the most frequently identified pharmaceuticals in aquatic environments. Until now multiple examinations have shown adverse effects of NSAIDs on life functions of aquatic organisms even in low concentrations. However, there is still lack of data about toxic

Planlösning i bostäder som en del av det passiva brandskyddet

Det finns i dagsläget flertalet tekniska lösningar för att begränsa konsekvenser av bränder i bostäder. Exempel på sådana kan vara sprinkler och brandvarnare. Ytterligare möjligheter för att reducera konsekvenser av brand i bostäder finns, där planlösningar i bostäder borde kunna användas som ett komplement till övrigt brandskydd. Syftet med examensarbetet är därför att undersöka planlösningar i bThe aim of this thesis is to investigate the impact of floor plan parameters in a residential dwelling regarding the consequences of fire that may endanger human life and health. The thesis follows a case study methodology and investigates isolated parameters in floor plans using CFD and CFAST modelling. The results are compared to a default case and a conclusion regarding the importance of parame