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The aim of the study was to evaluate the anatomic suitability for endovascular abdominal aneurysm repair (EVAR) according to instructions for use (IFUs) of three commercially available bifurcated stent graft devices and explore the possible benefits of low-profile delivery systems. Computed tomography scans of 241 patients with abdominal aortic aneurysm (AAA) were evaluated for suitability of Zeni

LARS2 has been previously identified as a potential type 2 diabetes susceptibility gene through the low-frequency H324Q (rs71645922) variant (minor allele frequency [MAF] 3.0%). However, this association did not achieve genome-wide levels of significance. The aim of this study was to establish the true contribution of this variant and common variants in LARS2 (MAF > 5%) to type 2 diabetes risk. We

Ovarian cancer linked to Lynch syndrome represents a rare subset that typically presents at young age as early-stage tumors with an overrepresentation of endometrioid and clear cell histologies. We investigated the molecular profiles of Lynch syndrome-associated and sporadic ovarian cancer with the aim to identify key discriminators and central tumorigenic mechanisms in hereditary ovarian cancer.

Challengers, as opposed to defenders,of the status quo ascribe more negative motives for the attitudes of their opponentsand more positive motives to their allies. This may be associated with a heightened social cost involved in challenging the generally considered good and true. Most social issues are associated with ideology, and conservatives display more prejudices than liberals. Hence, it is

We report a simple and versatile method to covalently immobilize molecularly imprinted polymer (MIP) nanoparticles on a Raman active substrate (Klarite) using a disulfide-derivatized perfluorophenylazide (PFPA-disulfide). Gold-coated Klarite was functionalized with PFPA-disulfide via a gold sulfur bond. Upon light radiation, the available azido groups were converted to highly reactive singlet perf

Water extracts of the bark of Uncaria tomentosa, a vine indigenous to South America, has been used for generations as an "immuno modulator". To understand the basis of this immuno modulatory effect we fed mice in their drinking water with C-Med 100, which is a commercially available water extract from Uncaria tomentosa. We found a dose-dependent increase in spleen cell numbers in the supplemented

Purpose: The purpose of this work was to evaluate the visibility of simulated lesions in 2D digital mammography (DM) and breast tomosynthesis (BT) images of patients. Methods: Images of the same women were acquired on both a DM system (Mammomat Novation, Siemens Healthcare, Erlangen, Germany) and a BT prototype system adapted from the same type of DM system. Using the geometrical properties of the

Within the framework of the European Land Arctic Physical Processes project and as part of the Danish Research Council's Polar Program, a study on trace gas exchange in a high-arctic ecosystem was conducted in NE Greenland, May-August 1997. On the basis of carbon dioxide flux measurements from three dominant surface types, this paper reports on the upscaling of such measurements from canopy to lan

Aim: To identify early predictors of outcome in infants born at 25 gestational weeks. Material and Methods: Data from a regional perinatal database (time-period 1995-2001, total n = 108 000 births) were used. Apgar scores were available in 92 preterm infants, born at 25 + 0 to 25 + 6 gestational weeks, and analyzed in relation to short-term outcome (180-day survival with, or without, severe brain

Popular Abstract in Swedish Förbränningsmotor är i dagens värld den mest använda kraftkällan för fordon. Förbränningsmotorn har kontinuerligt utvecklats och förbättrats sedan Nicolaus August Ottos och Rudolf Diesels dagar, och kommer att fortsätta att utvecklas långt in i framtiden. Ingen konkurrerande teknik har ännu på allvar utmanat förbränningsmotorns ställning. Det finns en lång rad tänkbara The prime mover in the world today is the Internal Combustion (IC) engine. The development and improvement of the internal combustion engines since Nicolaus August Otto and Rudolf Diesel has continued until today and will continue long into the future. No major competitor to the IC engine has yet emerged. There is a long list of potential competitors but they still have to prove their superiority

The aim of this study was to evaluate some bioassays that are different in principle: cell counting, colony forming assay, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT), sulforhodamine B (SRB), crystal violet, and alamarBlue, with respect to their ability to measure cisplatin-induced cell death of in vitro-cultivated squamous cell carcinoma of the head and neck (SCCHN). Cispl

Vertebrates possess different types of retinal specializations that vary in number, size, shape, and position in the retina. This diversity in retinal configuration has been revealed through topographic maps, which show variations in neuron density across the retina. Although topographic maps of about 300 vertebrates are available, there is no method for characterizing retinal traits quantitativel

In the last years, many vehicle manufacturers have introduced advancedriver support in some of their automobiles. One of those new featuresis Adaptive Cruise Control (ACC), which extends the conventionalcruise control system to control of relative speed and distance toother vehicles. In order to design an ACC controller it is suitable tohave a model on drivers' behavior. Our approach to find dynam

Popular Abstract in Swedish Avhandlingen behandlar substitutionsprincipen som den är formulerad i utbytesregeln i lagen om kemiska produkter. Denna lagregel tolkas med utgångspunkt i dess kontext i kemikalielagstiftningen. I avhandlingen klarläggs vad utbytesregeln innebär för den som hanterar kemikalier. Myndigheternas förvaltningsrättsliga befogenheter att genomdriva substitutionsprincipen underThe principle of substitution is, in national and international contexts, regarded as an important instrument when striving towards sustainable development and sustainable handling of chemicals.This thesis deals with the principle as it is formulated in the Swedish Act of Chemical Products. The implementation of this rule of substitution is studied from several aspects. The rule of substitution is

Popular Abstract in Swedish Är det möjligt att det pågår en hård kamp under våra fötter när vi tar en promenad i den Skånska lövskogen? Oftast tänker man på ett positivt förhållande mellan växter och marken's bakterier och svampar, där den autotrofa växten omvandlar luften's kol (C), i form av koldioxid, till organiskt C som därigenom blir tillgängligt för mikroorganismerna. Mikroorganismerna bryCompetition between and within species has been one of the most studied concepts in ecology. In this thesis the aim was to test the idea of plant-microbial competition for N and, by studying this interaction, to gain a better understanding of different N processes in soil. The research carried out seeks to investigate plant-microbial competition for N based on the definition that competition only

One of the most well-known facts about unit root testing in time series is that the Dickey--Fuller (DF) test based on OLS demeaned data suffers from low power, and that the use of GLS demeaning can lead to substantial power gains. Of course, this development has not gone unnoticed in the panel unit root literature. However, while the potential of using GLS demeaning is widely recognized, oddly eno

Mollusks have received increasing interest in ecotoxicological studies but so far the available scientific analyses of how their genes are affected by anthropogenic pollutants are scarce. The focus of this study is to identify an estrogen receptor (er) gene in the common prosobranch snail Bithynia tentaculata and to test a hypothesis that 17α-Ethinylestradiol (EE2) will modulate er gene expression

Severely disturbed habitats such as military training grounds, gravel pits and sand pits contribute to the species diversity of the agricultural landscape in Europe. They host a number of red-listed species not found elsewhere, illustrating that many plant species are threatened by extinction due to too little soil disturbance. Implementing a suitable disturbance regime is therefore crucial to ens

Objective To assess the efficacy of paquinimod, a new immunomodulatory small molecule, in a murine lupus model, and to evaluate its pharmacokinetics and tolerability in systemic lupus erythematosus (SLE) patients at doses predicted to be efficacious and safe and determine the maximum tolerated dose. Methods The efficacy of paquinimod was studied in lupus-prone MRL-lpr/lpr mice and compared with th