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ACTA & European Union perspectives

Abstract in UndeterminedProfessor Mylly suggests that the Lisbon Treaty opens a new avenue for the Commission when the internal legislative pathway becomes too complicated, demanding unanimity in decision-making. An alternative route would be to use the competence to enter into international agreements, where qualified majority is enough. The agreements may be phrased in such a way that they have

Malignant lymphoproliferative diseases in occupations with potential exposure to phenoxyacetic acids or dioxins : A register‐based study

The Swedish Cancer Environment Register (CER) is a linkage of census data (e.g., on occupations) with the Swedish Cancer Register. It has been used in different studies to generate hypotheses on occupational risk factors for malignant tumors. In this study the risk for malignant lymphoma and multiple myeloma in occupations with potential exposure to phenoxyacetic acids or other related substances

Experimental methods for measuring the breakup frequency in turbulent emulsification : A critical review

The growing interest in using population balance modeling to describe emulsification processes has spurred an interest in experimentally measuring the breakup frequency. This contribution classifies, compares, and critically reviews the different methods that have been suggested for measuring the breakup frequency, applicable to emulsification devices. Two major approaches can be seen in previous

Opportunities and challenges in implementing Smart Specialisation in Nordic ‘strong innovator’ regions

In this paper we consider the experience of implementing the Smart Specialisation Strategy (S3) in three regions in Finland, Norway and Denmark. We highlight the challenges each of these ‘strong innovator’ regions has faced in implementing S3. We elucidate the fact that each region faced different challenges when implementing S3. We extend a discussion around place-based policy, which is designed

πBO: Augmenting Acquisition Functions with User Beliefs for Bayesian Optimization

Bayesian optimization (BO) has become an established framework and popular tool for hyperparameter optimization (HPO) of machine learning (ML) algorithms. While known for its sample-efficiency, vanilla BO can not utilize readily available prior beliefs the practitioner has on the potential location of the optimum. Thus, BO disregards a valuable source of information, reducing its appeal to ML prac

Aspirin and NSAID use and the risk of COVID-19

Early reports raised concern that use of non-steroidal anti-inflammatory drugs (NSAIDs) may increase risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19). Users of the COVID Symptom Study smartphone application reported use of aspirin and other NSAIDs between March 24 and May 8, 2020. Users were queried daily about symptoms, COVID-19 testing, and healthcare seeki

Polarimetric relative pose estimation

In this paper we consider the problem of relative pose estimation from two images with per-pixel polarimetric information. Using these additional measurements we derive a simple minimal solver for the essential matrix which only requires two point correspondences. The polarization constraints allow us to pointwise recover the 3D surface normal up to a two-fold ambiguity for the diffuse reflection.

SPECIES ASSEMBLIES AND SEASONAL SUCCESSION OF DINOFLAGELLATES

Seasonality of dinoflagellate blooms and dinoflagellate assemblies are not random. Yet, bloom events and the specific appearance of species is difficult to predict and sometimes appears stochastic. Nevertheless, it has been established that both abiotic and biotic factors determine species assemblies, as well as the available species pool. The physical environment, especially nutrients and mixing/

The Fertile Desert : A History of the Middle Euphrates Valley until the Arrival of Alexander

The Fertile Desert studies a region of the Euphrates Valley between the Balikh and Khabour in Syria that remains little known. Partial reports, isolated interventions, and proposals for a hypothetical reconstruction of the relationship and processes of cultural expansion between Mesopotamia and the Jazira suggest that the Euphrates has always been a major traffic route. But suggestions on a map mu

Hormone replacement therapy with estrogens may reduce lamotrigine serum concentrations : A matched case–control study

Lamotrigine (LTG) is an antiepileptic drug that is metabolized via glucuronidation. Since the glucuronidizing enzyme is inducible by estrogens, LTG serum concentrations may fall by 50–60% when combined with hormonal contraceptives that contain ethinyl estradiol (EE). Little is known about a possible interaction between estrogens used for hormone replacement therapy (HRT) and LTG, and the few avail

Acqui-hiring and deep-tech ventures : evidence from Sweden

Recently, acqui-hiring, which refers to the acquisitions driven by gaining access to target human capital, has emerged as a proliferating phenomenon in acquisitions of small technology firms. However, we still know little about this phenomenon, particularly outside the community of Silicon Valley. This study sheds new light on the nature of acqui-hiring by focusing on what drives acqui-hiring. Usi

Search for long-lived, massive particles in events with displaced vertices and multiple jets in pp collisions at √s = 13 TeV with the ATLAS detector

A search for long-lived particles decaying into hadrons is presented. The analysis uses 139 fb−1 of pp collision data collected at s = 13 TeV by the ATLAS detector at the LHC using events that contain multiple energetic jets and a displaced vertex. The search employs dedicated reconstruction techniques that significantly increase the sensitivity to long-lived particles decaying in the ATLAS inner

PON-Sol2 : Prediction of effects of variants on protein solubility

Genetic variations have a multitude of effects on proteins. A substantial number of variations affect protein–solvent interactions, either aggregation or solubility. Aggregation is often related to structural alterations, whereas solubilizable proteins in the solid phase can be made again soluble by dilution. Solubility is a central protein property and when reduced can lead to diseases. We develo

Amyloid-PET imaging predicts functional decline in clinically normal individuals

Background: There is good evidence that elevated amyloid-β (Aβ) positron emission tomography (PET) signal is associated with cognitive decline in clinically normal (CN) individuals. However, it is less well established whether there is an association between the Aβ burden and decline in daily living activities in this population. Moreover, Aβ-PET Centiloids (CL) thresholds that can optimally predi

Gaussian process learning of nonlinear dynamics

One of the pivotal tasks in scientific machine learning is to represent underlying dynamical systems from time series data. Many methods for such dynamics learning explicitly require the derivatives of state data, which are not directly available and can be approximated conventionally by finite differences. However, the discrete approximations of time derivatives may result in poor estimations whe

Human resource challenges in health systems : evidence from 10 African countries

Sub-Saharan Africa has fewer medical workers per capita than any region of the world, and that shortage has been highlighted consistently as a critical constraint to improving health outcomes in the region. This paper draws on newly available, systematic, comparable data from 10 countries in the region to explore the dimensions of this shortage. We find wide variation in human resources performanc

To continue or not to continue? Antipsychotic medication maintenance versus dose-reduction/discontinuation in first episode psychosis : HAMLETT, a pragmatic multicenter single-blind randomized controlled trial

Background: Antipsychotic medication is effective for symptomatic treatment in schizophrenia-spectrum disorders. After symptom remission, continuation of antipsychotic treatment is associated with lower relapse rates and lower symptom severity compared to dose reduction/discontinuation. Therefore, most guidelines recommend continuation of treatment with antipsychotic medication for at least 1 year

Identification of women and girls with iron deficiency in the reproductive years

Iron deficiency (ID) is the most common micronutrient deficiency in the world. It is of concern for women and girls of reproductive age as, despite frequent normalization, excessive menstrual blood loss and the iron demands associated with pregnancy increase the risk of developing an ID. Iron deficiency reduces health-related quality of life with symptoms of fatigue, heart palpitations, difficulty

Experimental verification of a scalable protocol for vehicle platooning

This paper is concerned with a recently proposed scalable protocol for vehicle platooning, known as the serial consensus protocol. This achieves coordination of second-order integrator systems through a series connection of first-order conventional consensus protocols, and has been theoretically shown to have advantageous stability and performance properties. We implement this protocol on a vehicl

On properties of hydraulic equilibria in district heating networks

District heating networks are an integral part of the energy system in many countries. In future smart energy systems, they are expected to enhance energy flexibility and support the integration of renewable and waste energy sources. An important aspect of these networks is the control of flow rates, which dictates the heat delivered to consumers. This paper concerns the properties of flow rates i