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Efficient Adaptive MCMC Through Precision Estimation

The performance of Markov chain Monte Carlo (MCMC) algorithms like the Metropolis Hastings Random Walk (MHRW) is highly dependent on the choice of scaling matrix for the proposal distributions. A popular choice of scaling matrix in adaptive MCMC methods is to use the empirical covariance matrix (ECM) of previous samples. However, this choice is problematic if the dimension of the target distributi

Calibrating a market model with stochastic volatility to commodity and interest rate risk

Based on the multi-currency LIBOR Market Model, this paper constructs a hybrid commodity interest rate market model with a stochastic local volatility function allowing the model to simultaneously fit the implied volatility surfaces of commodity and interest rate options. Since liquid market prices are only available for options on commodity futures, rather than forwards, a convexity correction fo

Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function

A major challenge in neuroscience is to resolve the connection between gene functionality, neuronal circuits, and behavior. Most, if not all, neuronal circuits of the adult brain contain a glutamatergic component, the nature of which has been difficult to assess because of the vast cellular abundance of glutamate. In this study, we wanted to determine the role of a restricted subpopulation of glut

Solvatochromism of dye-labeled dendronized polymers of generation numbers 1–4: comparison to dendrimers

Two series of dendronized polymers (DPs) of generations g = 1–4 with different levels of dendritic substitution (low and high) and a solvatochromic probe at g = 1 level are used to study their swelling behavior in a collection of solvents largely differing in polarity as indicated by the Kamlet–Taft parameters. This is done by measuring the UV-Vis spectra of all samples in all solvents and determi

Universities and inclusiveness : An overview

This concluding chapter gives an overview of social inclusiveness at universities in the 11 countries covered in this book. Which are the most important obstacles for young people to do higher education studies, why do such obstacles remain, and what, if anything, is being done about it? One interesting aspect of the country studies is the difference when it comes to the role of private universiti

Lokala rörelser av grågäss Anser anser i södra Sverige utanför häckningstiden

During 1984–2009, Greylag Geese Anser anser were neck-banded at two lakes six kilometres apart in southwest Scania, southernmost Sweden: 2308 at lake Yddingen and 633 at Klosterviken (part of lake Bör-ringe). Through 2013 we recorded 51 132 and 29 937 re-sightings, respectively. We analyse the distribution patterns within Scania during the post-breeding months July–March. In spite of the short dis

Quality assessment of biobanked nucleic acid extracts for downstream molecular analysis

Sample quality is of major importance when conducting molecular analysis of nucleic acids, and factors such as degradation, presence of impurities, and enzymatic inhibitors may have a significant impact on the quality of data. Issues of quality assessment become more important as the increased use of biobanking means that whole blood samples are being stored for longer periods. A range of commerci

Political vs Everyday Forms of Governance in Uzbekistan: the Illegal, Immoral and Illegitimate Politics and Legitimacy in Post-Soviet Eurasia

Based on extensive ethnographic fieldwork in Uzbekistan, this article looks at the way official state narratives are challenged by silent, unorganised, often unaware gestures of resistance at the bottom of a society. Footing on a framework suggested by Scott’s definition of infrapolitics (2012), we propose to incorporate informal practices in a definition of informality that is more inclusive and

Uncommon sense : A review of challenges and opportunities for aggregating disaster risk information

The ambition to integrate disaster risk information from multiple stakeholders exists at different scales in any country and serve to control the risk of losses within companies, organizations and countries as a whole. Against the backdrop of extensive deliberations with risk management professionals in Sweden, this paper is based on an interdisciplinary scoping study of literature aimed to enhanc

Composition and effect of soaking on starch digestibility of Phaseolus vulgaris (L.) cv. 'Mayocoba'

Common beans from Mayocoba variety were soaked in different solutions, cooked, stored and evaluated for cooking time, chemical composition and in vitro starch digestibility. Soaking decreased cooking time; the lowest value (149 min) was obtained when a sodium chloride (1%) and sodium bicarbonate (0.75%) mixture was used. Total starch content in samples soaked in water, sodium chloride or sodium bi

In vitro starch digestibility and predicted glycemic index of corn tortilla, black beans, and tortilla-bean mixture : Effect of cold storage

People in the rural areas of Mexico consume corn tortillas and beans as basic components of their diet. However, little is known about the nutritionally relevant features of starch present in such combined meals. The objective of the present study was to evaluate the in vitro bioavailability of starch in tortilla-bean mixtures stored at 4 °C for different times, as compared to that of corn tortill

The Collegial Project Course: a systematic way towards institutional change

This paper presents and discusses how to support disciplinary communities of academic teachersto create a lasting change in educational culture. By stressing the similarities with the fully accepted research culture and their research knowledge this have been possible. Evaluations consistentlyshow that participants appreciate the collegial approach. It offers them an opportunity to deal withchalle

Arabidopsis thaliana alternative dehydrogenases : A potential therapy for mitochondrial complex i deficiency? Perspectives and pitfalls

Background: Complex I (CI or NADH:ubiquinone oxidoreductase) deficiency is the most frequent cause of mitochondrial respiratory chain defect. Successful attempts to rescue CI function by introducing an exogenous NADH dehydrogenase, such as the NDI1 from Saccharomyces cerevisiae (ScNDI1), have been reported although with drawbacks related to competition with CI. In contrast to ScNDI1, which is perm

Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation

Parkinson's disease (PD) affects motor function through degenerative processes and synaptic transmission impairments in the basal ganglia. None of the treatments available delays or stops the progression of the disease. While α-synuclein pathological accumulation represents a hallmark of the disease in its idiopathic form, leucine rich repeat kinase 2 (LRRK2) is genetically associated with familia

Identifying representative case studies for ecosystem services mapping and assessment across Europe

A key task in the ESMERALDA project dealt with identifying appropriate case studies to test the ‘flexible methodology’ in its different stages of development. Case studies consist of working examples in which mapping and assessment of ecosystem services were applied to address specific decision-making problems. Testing is understood as an iterative process of co-learning that involves project part

Analysis of soil water dynamics in time and space by use of pattern recognition

This paper presents a method to use pattern recognition in the analysis of soil water dynamics in time and space simultaneously. Space‐time correlation structures are generated by use of a numerical model for the one‐dimensional unsaturated flow equation. By applying the method to various soil parameter combinations (unsaturated hydraulic conductivity and dispersion coefficient) and length of infi

Consumer acceptance and value in use-oriented product-service systems : Lessons from Swedish consumer goods companies

In order to make our production and consumption systems more sustainable, there is a need to further explore and support novel business models with higher sustainability potential. Use-oriented product-service systems (u-PSS) are considered a promising alternative to traditional ownership-based business models, as they may result in lower environmental impacts. The presence of u-PSS in consumer go

Swedish healthcare under pressure

Swedish healthcare, run by local governments at both the regional (county) and the municipal levels, has been under pressure during the last 15 years, following increased scrutiny of performance and demand for cost-containment. Health-care expenditures per capita and levels of resource inputs have grown, but more slowly than in other EU countries. At the same time, the number of elderly people has

Detection of units with pervasive effects in large panel data models

The importance of units that influence a large number of other units in a network has become increasingly recognized in the literature. In this paper we propose a new method to detect such pervasive units by basing our analysis on unit-specific residual error variances subject to suitable adjustments due to the multiple testing issues involved. Accordingly, a sequential multiple testing (SMT) proc

Drivers of abrupt and gradual changes in agricultural systems in Chad

The countries in the Sahel are undergoing rapid changes due to a mixture of demographic, ecological, and economic transformations. Rural livelihoods in these countries are predominantly engaged in agriculture, which is a foundational component of both food security and the general economy. The relationships between ongoing socio-economic transformation and the agricultural sector are clearly impor