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Regime-based asset allocation has been shown to add value over rebalancing to static weights and, in particular, reduce potential drawdowns by reacting to changes in market conditions. The predominant approach in previous studies has been to specify in advance a static decision rule for changing the allocation based on the state of financial markets or the economy. This talk proposes the use of mo
Cultural and creative activities are today described as central to regional and urban development by politicians and governments. Creative city policies are often aiming at economic benefits for the city itself, and there are normative purposes with many research studies as well as projects undertaken (Eckardt 2005; Markusen and Gadwa 2010; Kovacs 2011). Creative city policy is often oriented towa
For elderly patients with mantle cell lymphoma (MCL), there is no defined standard therapy. In this multicenter open-label phase I/II trial we evaluated the addition of lenalidomide (LEN) to rituximab-bendamustine (R-B) as first-line treatment to elderly MCL patients. Patients >65 years with untreated MCL, stage II-IV were eligible for inclusion. Primary endpoints were maximally tolerable dose (MT
Introduction: Haemophilia treatment varies significantly between individuals, countries and regions and details of bleed rates, factor consumption and injection frequency are often not available. Aim: To provide an overview of the FVIII/FIX treatment practice and outcome for patients with haemophilia A (HA) or haemophilia B (HB) across Europe. Methods: Non-interventional, 12-month retrospective st
Background Abiraterone acetate (AA) prolongs survival in metastatic castration-resistant prostate cancer (mCRPC) patients. To measure treatment response accurately in bone, quantitative methods are needed. The Bone Scan Index (BSI), a prognostic imaging biomarker, reflects the tumour burden in bone as a percentage of the total skeletal mass calculated from bone scintigraphy. Objective To evaluate
Cardiac arrest (CA) survivors may experience cognitive, physical, or emotional problems that can affect their return to everyday activities and quality of life. To improve longterm outcomes, interventions after hospital discharge may be needed. A follow-up plan to identify CA survivors with increased risk of residual cognitive, physical, or emotional problems is important to target interventions a
In the emerging field of Internet of Things (IoT), where computerized devices are combined in creative new ways, there is a need to create Graphical User Interfaces (GUIs) for the systems being built, e.g. in the form of Android “apps”. This is generally a complicated, time consuming task. We report from a controlled experiment that evaluates a new approach for building GUIs that aims to make it e
The DyDOC model simulates the C dynamics of forest soils, including the production and transport of dissolved organic matter (DOM), on the basis of soil hydrology, metabolic processes, and sorption reactions. The model recognizes three main pools of soil C: litter, substrate (an intermediate transformation product), and humic substances. The model was used to simulate the behavior of C in the 0 ho
The present study examined plasma lipoprotein, lipoprotein lipase, hepatic lipase, and insulin levels in men with borderline hypertension (diastolic blood pressure 85 to 94 mm Hg) compared with age-matched normotensive control subjects (diastolic blood pressure less than or equal to 80 mm Hg, n = 75 + 75). High-density lipoprotein (HDL) subclasses were determined in a subset (n = 45 + 45). While t
Exopolysaccharides (EPS) are excreted by microorganisms into the surrounding environment and have been shown to have various physiological effects and are commonly used as food additives due to their rheological properties. Four commercially available microbial EPS with different polymeric structures and composition were tested in LDL receptor knock-out mice to investigate their effect on blood ch
Many northerly breeding shorebird species show a separation in timing of adult and juvenile migration. If, in addition to genetic control of migration, learning from experienced conspecifics is advantageous, juveniles should join adult birds during their first fall migration when possible. We here present a method to test if juveniles mix with adults during the period of overlap during southward m
We study deterministic algorithms for the gossiping problem in ad hoc radio networks under the assumption that each combined message contains at most b(n) single messages or bits of auxiliary information, where b is an integer function and n is the number of nodes in the network. We term such a restricted gossiping problem b(n) -gossiping. We show that rootn-gossiping in an ad hoc radio network on
Aims/hypothesis The Diabetes Prevention Program (DPP) lifestyle intervention successfully achieved its goal of increasing leisure physical activity levels. This current study examines whether the lifestyle intervention also changed time spent being sedentary and the impact of sedentary time on diabetes development in this cohort. Methods 3,232 DPP participants provided baseline data. Sedentary beh
Brevmall Postadress Lunds universitet, Box 117, 221 00 Lund Besöksadress Scheeletorget 1, Medicon Village E-post johanna.mellgren@fs.lu.se Webbadress www.fs.lu.se Research Services Johanna Mel lg ren Research Funding Advisor Program for art history and archeology, Marcus and Amalia Wallenberg Foundation. Last day to apply: 1 June 2022. The Foundation announces a call for a program for research wit
https://www.staff.lu.se/sites/staff.lu.se/files/2022-04/ManagementRules2022_MAW_art_archeology.pdf - 2026-05-07
Composition is a practice of key importance in software engineering. When real-time applications are composed, it is necessary that their timing properties (such as meeting the deadlines) are guaranteed. The composition is performed by establishing an interface between the application and the physical platform. Such an interface typically contains information about the amount of computing capacity
Microsoft Word - Draft programme LERU DSS Heidelberg.docx 1 Heidelberg University Proposal for a LERU Doctoral Summer School in Heidelberg 2023 Concepts of intervention science applied to global challenges Equipping the next generation of scientists with understanding of main concepts and methods of intervention science and applying them to the converging global challenges: climate change, pandemi
Antimicrobial resistance (AMR) is a growing problem worldwide as more drug-resistant bacteria are identified. However, resistance is comparably rare against antibiotics that target the cytoplasmic membrane. Membrane thickness is an important factor for the mode of action of these antibiotics, and difficult to study. Thus, constructing a biosensor to measure membrane thickness in vivo is of great i
Popular Abstract in Swedish 1100-talet var en mycket dynamisk och händelserik tid i dansk historia. Under detta århundrade ägde en rad samhällsförändringar rum som kom att påverka de allra flesta. På landsbygden samlades bebyggelsen i byar samtidigt som jordbruket rationaliserades och naturresurserna utnyttjades mer storskaligt. I städerna utvecklades penningekonomin och en mångfacetterad varuprodThe Early Middle Ages, comprising the period ca. 1000-1250, is usually described as a dynamic and eventful time, when many spheres of society underwent radical changes. The aim of this dissertation is to link these processes together in an overall holistic description of medieval society. The intention is thus to provide a "total historical" account of early medieval Denmark by means of a broad in
Objectives: To investigate gender differences in daily smoking prevalence in different age groups in southern Sweden. Methods: The 2004 public-health survey in Skåne is a cross-sectional study. A total of 27,757 persons aged 18-80 years answered a postal questionnaire, which represents 59% of the random sample. A logistic regression model was used to investigate the associations between gender and
