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Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform

Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h

Group A streptococci induce stronger M protein-fibronectin interaction when specific human antibodies are bound

Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to manipulate the immune system through various mechanisms. GAS’ M protein constitutes a primary target of the immune system due to its spatial configuration and dominance on the bacterial surface. Antibody responses targeting the M protein have been shown to favor the conserved C region. Such antibodies (Abs) c

IgG Binds Escherichia coli Serine Protease EspP and Protects Mice From E. coli O157:H7 Infection

Shiga toxin-producing Escherichia coli O157:H7 is a virulent strain causing severe gastrointestinal infection, hemolytic uremic syndrome and death. To date there are no specific therapies to reduce progression of disease. Here we investigated the effect of pooled immunoglobulins (IgG) on the course of disease in a mouse model of intragastric E. coli O157:H7 inoculation. Intraperitoneal administrat

Development and validation of a machine learning-based model to predict isolated post-challenge hyperglycemia in middle-aged and elder adults : Analysis from a multicentric study

Introduction: Due to the high cost and complexity, the oral glucose tolerance test is not adopted as the screening method for identifying diabetes patients, which leads to the misdiagnosis of patients with isolated post-challenge hyperglycemia (IPH), that is., patients with normal fasting plasma glucose (<7.0 mmoL/L) and abnormal 2-h postprandial blood glucose (≥11.1 mmoL/L). We aimed to develop a

Access to Asylum : International refugee law and the globalisation of migration control. - The Raoul

Access to Asylum : International refugee law and the globalisation of migration control. - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Stra

https://rwi.lu.se/publications/access-to-asylum-international-refugee-law-and-the-globalisation-of-migration-control/ - 2026-04-24

Eight Brides for Twenty-Four Brothers

Eight Brides for Twenty-Four Brothers Four Brides for Twelve Brothers: How to Dutch Book a Group of Individually Rational Players 1 Luc Bovens London School of Economics and Political Science Dept. of Philosophy, Logic and Scientific Method L.Bovens@LSE.ac.uk You can’t be wise and in love at the same time. (Bob Dylan) Abstract. Wlodek Rabinowicz suggested in an e-mail conversation (2001) to me tha

https://www.fil.lu.se/hommageawlodek/site/papper/BovensLuc.pdf - 2026-04-24

MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Background: Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil maturation, survival, and mobilization. Attempts to target eosinophils for the treatment of asthma by means of IL-5 neutralization have only resulted in partial removal of airway eosinophils, and this warrants the development of more effec

Program ESSUG Användardagar 26-27 April

Program ESSUG:s användardagar 2022 via Zoom Tisdagen den 26 april (EBSCO deltar under denna eftermiddag) 13.00-13.05 Välkomna! 13.05-13.45 Presentation the new GOPAC/Global OPAC (Claus Wolf, Manager Library Service Engineer team) 30 min + 10 min frågor 13.45-13.50 Paus 13.50-14.20 Continued roll out and enhancements of the new EDS interface. Project updates (PM- team) 20 min + 10 min frågor 14.20-

https://www.ub.lu.se/sites/ub.lu.se/files/2022-05/Program%20ESSUG%20anv%C3%A4ndardagar%2026-27%20april.pdf - 2026-04-24

Gemensamma Förvaltningens Verksamhetsplan 2026

FVP 2026.indd Verksamhetsplan 2026 GEMENSAMMA FÖRVALTNINGEN | LUNDS UNIVERSITET GEMENSAMMA FÖRVALTNINGENS VERKSAMHETSPLAN 2026 © Lunds universitet 2026 www.lu.se lu@lu.se TRYCK Media-Tryck, LU Service, Lunds universitet www.mediatryck.lu.se media-tryck@service.lu.se Svanenmärkt trycksak, 341903 PROJEKTLEDARE Susanne Hägerström, Utveckling FORMGIVNING Stefan Andersson, LU Service TEXTBEARBETNING Su

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2026-01/Gemensamma%20f%C3%B6rvaltningens%20verksamhetsplan%202026.pdf - 2026-04-24

JoL Handlingsplan 2024-2027-2

240919 Soc ia lhögskolan Socialhögskolans handlingsplan för jämställdhet och lika villkor 2024-2027 I föreliggande dokument beskrivs Socialhögskolans arbete med jämställdhet och lika villkor (JoL). Del 1 utgörs av handlingsplanen, dvs utgångspunkterna för institutionens JoL-arbete. Del 2 utgörs av planerade, pågående och avslutade åtgärder i enlighet med handlingsplanens målsättningar. JOL-arbetet

https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/2026-01/JoL%20Handlingsplan%202024-2027-2.pdf - 2026-04-24

The assessment of patent pools under antitrust law, a comparative analysis

Denna uppsats behandlar de konkurrensrättsliga skillnaderna i EU-rätt och amerikans rätt rörande patentpooler. Genom patentpooler ges företag möjlighet att gemensamt samla sina patent inom ett visst tekniskt område och tillsammans licensera dem. Genom poolning av patent ökar möjligheterna för snabb utveckling samtidigt som licenskostnaderna minskar då samtliga nödvändiga patent blir tillgängliga gThis thesis identifies the differences in the antitrust regulations concerning patent pooling within the EU and the U.S. Patent pooling enables firms to jointly licence their patents as a package, gathering patents that are necessary in order to produce a certain product. Patent pooling allows faster development at lower costs, since firms can attain all necessary patents through one single licens

Metal Binding Tags - Characterisation, Use in Bioseparation and Applications of Green Fluorescent Fusion Proteins

Most of the recombinant proteins produced nowadays are fused to affinity tags, in order to facilitate their purification through affinity chromato-graphy. Out the different tags available, poly-histidine tags are among the most commonly used and can help purification through immobilised metal ion affinity chromatography (IMAC). In this thesis, we present different metal binding tags, and their af

Fab fragments imprinted SPR biosensor for real-time human immunoglobulin G detection

F(ab) fragments imprinted surface plasmon resonance (SPR) chip was prepared for the real-time detection of human immunoglobulin G (IgG). In order to attach polymerization precursor on SPR chip, the SPR chip surface was modified with allyl mercaptan. F(ab) fragments of the IgG molecules were prepared by papain digestion procedure and collected by fast protein liquid chromatography (FPLC) system usi

Kpl

Kpl Vårterminen 2016 Litteraturlista för NODB03, Muntlig danska, 7,5 hp, halvfart, kvällstid Fastställd av sektion 1 vid Språk- och litteraturcentrum, den 2 december 2015. Obligatorisk facklitteratur Koldtoft, Lone: Dansk udtaleøvebog for svenskere" (Bok i kompendieformat som säljes av läraren) Ljudfiler enligt lärarens anvisningar. Obligatorisk skönlitteratur Pape, Morten. Planen. (565 s.) Valfri

https://www.sol.lu.se/media/utbildning/dokument/kurser/NODB03/20161/NODB03_litt_kvll_KLAR_1.pdf - 2026-04-24

Jama lugar 2023 oi 230100 1695046175.41487

SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood Marija Lugar, MSc; Anne Eugster, PhD; Peter Achenbach, MD; Thekla von dem Berge, MD; Reinhard Berner, MD; Rachel E. J. Besser, MD; Kristina Casteels, MD; Helena Elding Larsson, MD; Gita Gemulla, MD; Olga Kordonouri, MD; Annett Lindner; Markus L

https://www.gppad.lu.se/sites/gppad.lu.se/files/2023-10/jama_lugar_2023_oi_230100_1695046175.41487.pdf - 2026-04-24

Jama lugar 2023 oi 230100 1695046175.41487

SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood Marija Lugar, MSc; Anne Eugster, PhD; Peter Achenbach, MD; Thekla von dem Berge, MD; Reinhard Berner, MD; Rachel E. J. Besser, MD; Kristina Casteels, MD; Helena Elding Larsson, MD; Gita Gemulla, MD; Olga Kordonouri, MD; Annett Lindner; Markus Lundgren, MD; Denise Müller, BSc; Mariusz Oltarzewski, PhD; Anne Rochtus, MD; M

https://www.gppad.lu.se/sites/gppad.lu.se/files/2024-01/jama_lugar_2023_oi_230100_1695046175.41487.pdf - 2026-04-24

Enhancement Requests 2023

Presentation template with LiU typography The management of enhancement requests – a customer perspective EBSCO Systems Swedish User Group Annual meeting 2023 Eva Sejmyr, Senior Librarian and System Manager, Linköping University Library Let's explore the management of enhancement requests from a customer perspective, with examples from Linköping University Library and ESSUG. 2023-04-26The manageme

https://www.ub.lu.se/sites/ub.lu.se/files/2023-05/Enhancement%20requests%202023.pdf - 2026-04-24