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IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies

The important bacterial pathogen Streptococcus pyogenes secretes IdeS (immunoglobulin G-degrading enzyme of S. pyogenes), a proteinase that cleaves human immunoglobulin G (IgG) antibodies in the hinge region resulting in Fc (fragment crystallizable) and F(ab')2 (fragment antigen-binding) fragments and protects the bacteria against phagocytic killing. Experiments with radiolabeled IdeS and flow cyt

Randomized Trial of a Palliative Care Intervention to Improve End-of-Life Care Discussions in Patients With Metastatic Breast Cancer

Background: Studies show that early, integrated palliative care (PC) improves quality of life (QoL) and end-of-life (EoL) care for patients with poor-prognosis cancers. However, the optimal strategy for delivering PC for those with advanced cancers who have longer disease trajectories, such as metastatic breast cancer (MBC), remains unknown. We tested the effect of a PC intervention on the documen

Preclinical evaluation of (111)In-DTPA-INCA-X anti-Ku70/Ku80 monoclonal antibody in prostate cancer.

The aim of this investigation was to assess the Ku70/Ku80 complex as a potential target for antibody imaging of prostate cancer. We evaluated the in vivo and ex vivo tumor targeting and biodistribution of the (111)In-labeled human internalizing antibody, INCA-X ((111)In-DTPA-INCA-X antibody), in NMRI-nude mice bearing human PC-3, PC-3M-Lu2 or DU145 xenografts. DTPA-conjugated, non-labeled antibody

New aspects of voltage-gated calcium channel regulation in pancreatic beta-cells - Relevance for insulin release and type 2 diabetes

Popular Abstract in German Spannungsgesteuerte Kalziumkanäle haben eine große Bedeutung in vielen elektrisch erregbaren Zellen, wie z.B. in Nervenzellen und pankreatischen beta-Zellen. Hier werden sie folgendermaßen aktiviert: In der Nahrung enthaltener Traubenzucker (Glukose) wird nach einer Mahlzeit über den Blutstrom im Körper verteilt und in die beta-Zellen über Glukosetransporter aufgenommen.Voltage-gated Ca2+ channels are essential transducers of cellular signals in many electrically excitable cells. In the pancreatic beta-cell they mediate controlled Ca2+ influx, which is the final trigger for Ca2+ dependent release (exocytosis) of the blood glucose lowering hormone insulin. Several subtypes of voltage-gated Ca2+ channels are known and the L-type has been found to be the main contri

Antiinflammatorisk kost – vad vet vi? – Vetenskap och Hälsa

Antiinflammatorisk kost – vad vet vi? – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Antiinflammatorisk kost – vad vet vi? 2022-06-01 Både Medelhavskosten, som är rik på frukt, grönsaker, bönor, omättade fetter, fibrer och den Nordiska kosten som består av mycket fisk,

https://www.vetenskaphalsa.se/antiinflammatorisk-kost/ - 2026-06-11

Intonal 2024 broschyr A5

WWW.IAC.LU.SE #INTERARTSCENTER Acousmatic Concerts at IAC PROGRAMME RED ROOM Thursday, 25 April 21:00 FRANCESCO DEL NERO | SOUND SPACES Robin Sandquist Hispers (6’) Luc Ferrari (1929–2005) Presque rien avec files (14’) Juan Carlos Vasquez Chanel zero (8’) Adele Marcia Kosman If it were for me you’d piece me up (6’) Luca Guidarini Apprendere dal fango (7’) 22:30 FABIO MONNI Luc Ferrari (1929–2005)

https://www.iac.lu.se/sites/iac.lu.se/files/2025-08/Intonal_2024_broschyr_A5.pdf - 2026-06-12

Create an accessibility statement

According to the Act on Accessibility to Digital Public Services (2018:1937), if you have a website in the joint web solution for Lund University, you must provide an accessibility statement for your website. You also need to provide a form for reporting accessibility issues. Ready-made form pages for these are available in Drupal linked to your website, and on this page we will go through how to

https://www.webbpublicering.lu.se/guides-english/create-accessibility-statement - 2026-06-11

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S & P Sprache und Pragmatik Arbeitsberichte 53 Britt-Marie Ek Das Präsens als Tempus konkreter und imaginärer Bildbeschreibung 1 Britt-Marie Ek & Mikael Nystrand Das schwedische Präsens als Übersetzungsstrategie beim deutschen Referatkonjunktiv 25 Edith Ekberg Frei versus fakultativ: Über die Interpretation der Dativphrase in deutschen ditransitiven Konstruktionen aus einer konstruktionsgrammatisc

https://www.sol.lu.se/fileadmin/user_upload/amnen/tyska/Sprache___Pragmatik_Vol._53_2013.pdf - 2026-06-11

Marju Orho-Melander: Gener och diet i samspel – Vetenskap och Hälsa

Marju Orho-Melander: Gener och diet i samspel – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Marju Orho-Melander: Gener och diet i samspel 2011-03-17 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Genetiska faktorer har stor betydelse f

https://www.vetenskaphalsa.se/marju-orho-melander-gener-och-diet-i-samspel/ - 2026-06-11

Towards alkali-stable polymers and hydroxide exchange membranes functionalized with alicyclic quaternary ammonium cations

In the current work, cationic polymers functionalized with N-alicyclic quaternary ammonium (QA) cations were synthesized and characterized as potential hydroxide exchange membranes (HEMs) for application in fuel cells. Three different polymers, namely poly(arylene ether sulfone), spiro-ionene and poly(arylene alkylene), were explored as polymer backbones for the HEMs. Various mono- and spirocyclic

Absolute and Relative Risk of Cardiovascular Disease in Men With Prostate Cancer: Results From the Population-Based PCBaSe Sweden.

PURPOSE Cardiovascular disease (CVD) is a potential adverse effect of endocrine treatment (ET) for prostate cancer (PC). We investigated absolute and relative CVD risk in 76,600 patients with PC undergoing ET, curative treatment, or surveillance. METHODS PCBaSe Sweden is based on the National Prostate Cancer Register, which covers more than 96% of PC cases. Standardized incidence ratios (SIRs) and

Surface water chemistry and nitrate pollution in Shimabara, Nagasaki, Japan

Groundwater is a finite resource that is threatened by pollution all over the world. Shimabara City, Nagasaki, Japan, uses groundwater for its main water supply. During recent years, the city has experienced severe nitrate pollution in its groundwater. For better understanding of origin and impact of the pollution, chemical effects and surface–groundwater interactions need to be examined. For this

News

2026 Gordon Research Conference on Image Science, April 26 - May 1, 2026:Leading experts in imaging will gather for five days of talks, discussions, and poster sessions, exploring cutting-edge advances across optical, MRI, X-ray, and other imaging modalities. The conference highlights innovations in instrumentation, computational methods, and AI, tackling challenging scenarios from biology to astr

https://www.fysik.lu.se/en/education/xanadu-graduate-research-school/news - 2026-06-11

2012-09-17

Enclosure  1 Delagated  decisions Travel  Grants Name Granted  amount Conference  /  Course  &  dates Decision Date  granted Ulrich  Pfisterer 15000 Cold  Spring  Harbour  Laboratory  Course  –  Single  Cell  Analysis  (6  –  19  June,  2012) S  Iwarsson 4/26/12 Maria  H  Nilsson 7000 16 th  International  Congress  of  Parkinson’s  Disease  and   Movement  Disorders  (17-­‐21  June  2012) C  Lund

https://www.multipark.lu.se/sites/multipark.lu.se/files/2012-09-17.pdf - 2026-06-13

History

LUNARC was formed as a collaboration between groups in Theoretical Chemistry, Physical Chemistry 2, and Structural Mechanics in 1986. The founding members were later joined by Theoretical Physics and in 1996, LUNARC was transformed into a centre for scientific and technical computing at Lund University. Together with five other centres, LUNARC became a part of the Swedish National Infrastructure f

https://www.lunarc.lu.se/about/history - 2026-06-11

A variant in the transcription factor 7-like 2 (TCF7L2) gene is associated with an increased risk of gestational diabetes mellitus.

Aims/hypothesis Genetic and epidemiological studies suggest an association between gestational diabetes mellitus and type 2 diabetes. Both are polygenic multifactorial disorders characterised by beta cell dysfunction and insulin resistance. Our aim was to investigate whether common genetic variants that have previously been associated with type 2 diabetes or related phenotypes would also confer ri

Dietary intake of acrylamide and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

In 1994, acrylamide (AA) was classified as a probable human carcinogen by the International Agency for Research on Cancer. In 2002, AA was discovered at relatively high concentrations in some starchy, plant-based foods cooked at high temperatures. A prospective analysis was conducted to evaluate the association between the dietary intake of AA and ductal adenocarcinoma of the exocrine pancreatic c