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Purpose: To assess performance of a biomarker-based score that predicts the five-year risk of diabetes (Diabetes Risk Score, DRS) in an independent cohort that included 15-year follow-up. Method: DRS was developed on the Inter99 cohort, and validated on the Botnia cohort. Performance was benchmarked against other risk-assessment tools comparing calibration, time to event analysis, and net reclassi
OBJECTIVE: To synthesise evidence related to the dissemination and implementation (D&I) of injury prevention interventions for female, woman and/or girl (female/woman/girl) athletes.DESIGN: Scoping review.DATA SOURCES: MEDLINE, APA PsycInfo, Cochrane Databases for Systematic Review, Cochrane Central Register for Controlled Trials Registry, EMBASE, CINAHL, SPORTDiscus, ERIC, ProQuest Dissertati
BackgroundWorkplace sexual harassment remains a persistent issue in Sweden. Research about organisational antecedents has been criticised for being limited in scope, possibly overlooking contextual factors relevant for the occurrence of sexual harassment. This study examined two factors capturing aspects of organisational climate, perceived relational justice and authoritarian treatment, and their
OBJECTIVE: This study evaluated the effects of a 6-week osteoarthritis (OA) exercise and education intervention on metabolic health markers, including blood pressure (BP), glycated haemoglobin (HbA1c), high-density lipoprotein (HDL), cholesterol levels and weight in individuals with both OA and diabetes.METHODS: Data originated from the Swedish Osteoarthritis and Diabetes cohort, which is composed
Background: Alcohol use disorder (AUD) is associated with an enormous burden of disease and cost to society. The dopamine deficiency hypothesis posits that negative reinforcement generated by a low brain dopamine state drives ethanol intake. Here, we evaluated the efficacy and safety of combined administration of two dopamine-enhancing drugs, varenicline (a partial nicotinic acetylcholine receptor
BACKGROUND: Brain-derived neurotrophic factor (BDNF) plays a critical role in neuronal development and neural connectivity, and has been implicated in the pathophysiology of Major Depressive Disorder (MDD). However, its predictive value for MDD onset remains unclear. This study examined whether baseline BDNF levels are associated with incident MDD in middle-aged women.MATERIAL AND METHODS: In this
BACKGROUND: This study aimed to evaluate the prevalence of pathogenic/likely pathogenic cardiomyopathy variant carriers in a multiancestry US population and examine the risk of adverse clinical outcomes. METHODS: This retrospective cohort study included multiancestry US adults aged ≥18 years with sequencing data from the All of Us Research Program. Pathogenic/likely pathogenic variants in cardiomy
An integrated framework is introduced and applied to assess the health impact of airborne pollution with greater physiological relevance, moving beyond conventional exposure metrics. Measured particle number size distribution data was integrated with a regional respiratory tract deposition fractions to estimate total and alveolar deposited particle surface area concentrations. Land use regression
Introduction: Assessing suicide risk in clinical settings is challenging, as conventional self-report scales have limited predictive validity. The Death Implicit Association Test (D-IAT) was developed to explore implicit associations related to death and the self-concept. However, it omits the emotional association with death that may be crucial in suicide risk assessment. This cross-sectional stu
Utvecklingsenheten Postadress Campus Helsingborg Box 882, 251 08 Helsingborg Besöksadress Universitetsplatsen 2, 252 25 Helsingborg Telefon, 042-35 65 19, 042- 35 65 00 (växel) E-post carola.fors@ch.lu.se Webbadress www.ch.lu.se 1 (6) Minnesanteckningar från Campusgruppsmöte 2025-04-09 Närvarande: Charlotta Johnsson Rektor, Utvecklingsenheten Jerker Jacobsson Utvecklingsenheten Julia Luttrup Utvec
https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2025-04/Campusgruppen%2020250409%20minnesant.pdf - 2026-07-01
The aim of this thesis was to study nurse assistants’ experience of palliative care and to investigate how an intervention with a focus on a palliative care approach in residential care facilities influenced the nurse assistants and their work situation. The thesis is based on two qualitative and two quantitative studies, focusing on nurse assistants working at residential care facilities for olde
Representationskompetensen hos den verkställande direktören i svenska aktiebolag regleras genom 8 kap. 36 § ABL och därigenom rekvisitet ”löpande förvaltning” i 8 kap. 29 § ABL. Vad denna löpande förvaltning omfattar är dock inte helt tydligt och kan variera kraftigt mellan olika typer av bolag och situationer. Detta kan skapa såväl praktiska som juridiska problem för både bolag och den verkställaThe legal capacity for Chief Executive Officers (CEO) in Swedish corporations is regulated through the legal condition “everyday operations” in Chapter 8, 36 § of the Swedish Companies Act of 2005. What is meant with “everyday operations” is not completely clear and can vary massively between different kinds of companies and situations. This may cause problems from both a practical and a jurisdict
Elevated cystatin C in blood reflects impaired glomerular filtration rate (GFR), but current cystatin C assays, based on polyclonal antibodies and immunoturbidimetric or nephelometric detection, have several limitations. We evaluated a new immunoassay based on monoclonal antibodies in samples from patients with and without chronic kidney disease (CKD). The study enrolled 170 men without known CKD
Den här uppsatsen tar upp innehållsstrukturens betydelse för översättningen av några inledande kapitel av Fernando Savaters bok Las preguntas de la vida. Uppsatsen inleds med en textanalys som följer analysmodellen i Hellspong & Ledin (1997). Därefter följer uppsatsens huvuddel som består dels av en genomgång av textens hierarkiskt ordnade innehåll och dels av exempel på hur denna innehållsstr
Background. In metastatic colorectal cancer, mutation testing for KRAS exon 2 is widely implemented to select patients with wild-type tumors for treatment with the monocloncal anti-EGFR antibodies cetuximab and panitumumab. The added predictive value of additional biomarkers in the RAS-RAF-MAPK and PI3K-AKT-mTOR pathways in colorectal cancer is uncertain, which led us to systematically review the
Over three-quarters of the world’s poor live in rural areas and many of them depend on agriculture to earn a living. In a context of climate change, Agriculture, Forestry and Other Land Use (AFOLU) is addressed as one of the main sources of Greenhouse Gas (GHG) emissions. Hence, the sustainability transition in the agricultural sector has become one of the most prominent development areas in the 2
