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Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice.

There is a class of oligodendrocyte progenitors, called O-2A progenitors, that is characterized by expression of platelet-derived growth factor &agr;-receptors (PDGFR(&agr;)). It is not known whether all oligodendrocytes are derived from these PDGFRalpha-progenitors or whether a subset(s) of oligodendrocytes develops from a different, PDGFR alpha-negative lineage(s). We investigated the re

Health care for the elderly: two cases of technology diffusion.

Diffusion of medical technology and the growing proportion of elderly people in the population are generally regarded as major contributors to the increasing health care expenditure in the industrialised world. This study explores the importance of one specific factor in this process, the change in the use of technology among elderly patients. In some instances, a new technology is first used amon

Surgical age and morbidity after arterial switch of transposition of the great arteries

Background: Although transposition of the great arteries (TGA) accounts for less than 5% of congenital heart disease, the clinical course is often dramatic with need for early diagnosis and careful preoperative care as well as advanced surgical correction and postoperative support. Since 1993, Lund is one of the two tertiary referral centers for pediatric cardiac surgery in Sweden, with nearly 400

Falls from Tractors in Older Age : Risky Behaviors in a Group of Swedish and Italian Farmers Over 65

The frequent mounting and dismounting the tractor required by many farming operations increases the risk of falls, particularly for older farmers. The present study explored the risk factors related to tractor ingress and egress in older farmers from two countries with a different tradition in terms of safety culture: Sweden and Italy. Eighteen male farmers aged 65 + (8 from Skåne region, southern

Fluorescence spectroscopy in tissue phantoms for improved depth resolution in tissue imaging

A way to determine the depth of an embedded fluorescent object, for example deep-lying tumors marked with a fluorescent probe, is to detect fluorescent light that has propagated through the medium at two different wavelength bands. A ratio can then be calculated between the corresponding intensities. The wavelength regions should be chosen such that there is a difference in the absorption in the m

Regulation of rod phototransduction machinery by ciliary neurotrophic factor

Ciliary neurotrophic factor (CNTF) promotes photoreceptor survival but also suppresses electroretinogram (ERG) responses. This has caused concerns about whether CNTF is detrimental to the function of photoreceptors because it is considered to be a potential treatment for retinal degenerative disorders. Here we report that the suppression of ERG responses is attributable to negative regulation of t

The perception of the benefits and drawbacks of internet usage by the elderly people

This project looks into the perception of the benefits and drawbacks of Internet usage by elderly people, born from the mid 1920s to the early 1940s, also known as the ‘silent generation’ (Lustria et al. in Health Informatics Journal 17(3):224–243, [1]). As governmental services are gradually becoming online, elderly people are required to use the Internet in order to complete the compulsory task(

Funding models in palliative care : Lessons from international experience

Background: Funding models influence provision and development of palliative care services. As palliative care integrates into mainstream health care provision, opportunities to develop funding mechanisms arise. However, little has been reported on what funding models exist or how we can learn from them. Aim: To assess national models and methods for financing and reimbursing palliative care. Desi

T50 D.3 Monitoring protocol for lighting and daylighting retrofits

This document presents a monitoring protocol to assess the overall performance of a lighting and/or daylighting retrofit of a building. This protocol covers four key aspects:1. Energy use;2. Retrofit costs;3. Photometric assessment;4. User assessment.This document develops each aspect in detail, presenting the required measurements and necessary equipment as well as providing guidelines for data a

Evaluation of the measurement properties of symptom measurement instruments for atopic eczema : A systematic review

Background: Symptoms have been identified as a core outcome domain for atopic eczema (AE) trials. Various instruments exist to measure symptoms in AE, but they vary in quality and there is a lack of standardization between clinical trials. Our objective was to systematically evaluate the quality of the evidence on the measurement properties of AE symptom instruments, thereby informing consensus di

A Novel Approach to Predict the Likelihood of Specific Ovarian Tumor Pathology Based on Serum CA-125: A Multicenter Observational Study.

BACKGROUND: The CA-125 tumor marker has limitations when used to distinguish between benign and malignant ovarian masses. We therefore establish likelihood curves of six subgroups of ovarian pathology based on CA-125 and menopausal status.METHODS: This cross-sectional study conducted by the International Ovarian Tumor Analysis group involved 3,511 patients presenting with a persistent adnexal mass

Maa 2015 opslag mq

M al m ö A rt A ca de m y 20 14  –  2 01 5 20 14  –  2 01 5 Gertrud Sandqvist Professor of Art Theory and the History of Ideas; Supervisor for the Doctoral Programme Dr. Sarat Maharaj Professor of Visual Art and Knowledge Systems; Supervisor for the Doctoral Programme Dr. Matts Leiderstam Professor of Fine Arts Haegue Yang Professor of Fine Arts Joachim Koester Professor of Fine Arts Emily Wardill

https://www.khm.lu.se/sites/khm.lu.se/files/maa_2015_opslag_mq.pdf - 2026-05-28

Prolonged Fatigue and Mental Health Challenges in Critical COVID-19 Survivors

Background: The aim of this study was to investigate the development of fatigue and mental illness between 3 and 12 months after critical COVID-19 and explore risk factors for long-lasting symptoms. Study Design and Methods: A prospective, multicenter COVID-19 study in southern Sweden, including adult patients (≥18 years) with rtPCR-confirmed COVID-19 requiring intensive care. Survivors were invi

Large regional variation in endovascular thrombectomy rates for acute ischemic stroke in Sweden

INTRODUCTION: Endovascular thrombectomy (EVT) is a significant improvement in the care of acute ischemic stroke (AIS) patients, but only a small portion of patients receive treatment. Our aim was to analyze EVT implementation in Sweden according to a set of key performance indicators (KPIs) for procedural and implementational effectiveness. METHODS: A nationwide prospective registry-based observ

Föräldraskap bakom skärmen - En intervjustudie med åtta småbarnsföräldrar

Studiens syfte var att nå en fördjupad förståelse av småbarnsföräldrars användande av interaktiva skärmar när de umgås med sina barn; vilken mening användandet har för individen och vilka följder detta kan få för relationen mellan förälder och barn. Semistrukturerade intervjuer genomfördes med åtta småbarnsföräldrar som sällan, ibland eller ofta använde sig av interaktiva skärmar. Tematisk analys The aim of this study was to gain a greater understanding of the usage of interactive screens by parents of young children, whilst interacting with their children; what role does the usage of interactive screens play for the individual and how does the usage affect the relationship between parent and child. Semi-structured interviews were conducted with eight parents of young children who rarely,

Higher Education for Girls in North American College Fiction 1886-1912

Twenty years after Vassar College welcomed the first American female undergraduates in 1865, the experiences of women college students began to be fictionalized in so-called college stories. This thesis shows how higher education is presented in the novels, collections of short stories, and serialized stories for female readers published before the United States was involved in the First World Wa

‘Someone must do it’ : multiple views on family’s role in end-of-life care – an international qualitative study

Background: Family is a crucial social institution in end-of-life care. Family caregivers are encouraged to take on more responsibility at different times during the illness, providing personal and medical care. Unpaid work can be overburdening, with women often spending more time in care work than men. Objectives: This study explored multiple views on the family’s role in end-of-life care from a

Alzheimer Disease Blood Biomarkers in Patients with Out-of-Hospital Cardiac Arrest

Importance: Blood phosphorylated tau (p-tau) and amyloid-β peptides (Aβ) are promising peripheral biomarkers of Alzheimer disease (AD) pathology. However, their potential alterations due to alternative mechanisms, such as hypoxia in patients resuscitated from cardiac arrest, are not known. Objective: To evaluate whether the levels and trajectories of blood p-tau, Aβ42, and Aβ40 following cardiac a

Challenges and opportunities for early career medical professionals in cardiovascular magnetic resonance (CMR) imaging : a white paper from the Society for Cardiovascular Magnetic Resonance

The early career professionals in the field of Cardiovascular Magnetic Resonance (CMR) face unique challenges and hurdles while establishing their careers in the field. The Society for Cardiovascular Magnetic Resonance (SCMR) has expanded the role of the early career section within the society to foster the careers of future CMR leaders. This paper aims to describe the obstacles and available oppo

Root system estimation based on satellite remote sensing : An applied study in Eastern Uganda

The density of roots is an important factor influencing the rate and magnitude of landslides. Due to the increased variability in climate, mainly rainfall, Eastern Uganda is severely struck by an increasing number of these mass movements, often with human casualties as one of the negative impacts. The aim of this study is to explore the possibility to estimate the depth and density of the root sys