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Experimental studies have suggested an atheroprotective role of interleukin (IL)-5 through the stimulation of natural immunoglobulin M antibody expression. In the present study we show that there are no associations between baseline levels of IL-5 and risk for development of coronary events or stroke during a 15.7 ± 6.3 years follow-up of 696 subjects randomly sampled from the Malmö Diet and Cance
To mark her 90th birthday on 24 January, MaerzMusik – Festival for Time Issues will devote a special programme to Éliane Radigue, highlighting the many facets of the composer’s work.
177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) is used clinically to treat metastasized or unresectable neuroendocrine tumors (NETs). Although 177Lu-DOTATATE is mostly well tolerated in patients, bone marrow suppression and long-term renal toxicity are still side effects that should be considered. Amino acids are often used to minimize renal radiotoxicity, however, they are associate
The association between blood pressure (BP) and bladder cancer (BC) risk remains unclear with confounding by smoking being of particular concern. We investigated the association between BP and BC risk among men using conventional survival-analysis, and by Mendelian Randomization (MR) analysis in an attempt to disconnect the association from smoking. We additionally investigated the interaction bet
As cardio metabolic disease manifestations tend to cluster in families there is a need to better understand the underlying mechanisms in order to further develop preventive strategies. In fact, genetic markers used in genetic risk scores, important as they are, will not be able alone to explain these family clusters. Therefore, the search goes on for the so called missing heritability to better ex
The following article investigates Keats’s expansion of the notion of Eros, arguing that it forms a dialectic relation between the self-sufficiency of the lover and a dream of mutual exchange between the subject and its object of desire. In order to discern the specific concerns of Keats in this regard, the study analyzes a letter sent to his friend John Hamilton Reynolds on the 19th of February 1The following article investigates Keats's expansion of the notion of Eros, arguing that it forms a dialectic relation between the self-sufficiency of the lover and a dream of mutual exchange between the subject and its object of desire. In order to discern the specific concerns of Keats in this regard, the study analyzes a letter sent to his friend John Hamilton Reynolds on the 19th of February 1
Parvalbumin- (PV-) containing basket cells constitute perisomatic GABAergic inhibitory interneurons innervating principal cells at perisomatic area, a strategic location that allows them to efficiently control the output and synchronize oscillatory activity at gamma frequency (30–90 Hz) oscillations. This oscillatory activity can convert into higher frequency epileptiform activity, and therefore c
Voltage-gated Ca2+ (CaV) channels trigger glucose-induced insulin secretion in pancreatic beta-cell and their dysfunction increases diabetes risk. These heteromeric complexes include the main subunit alpha1, and the accessory ones, including subunit gamma that remains unexplored. Here, we demonstrate that CaV gamma subunit 4 (CaVγ4) is downregulated in islets from human donors with diabetes, diabe
Background An increased rate of cell death by apoptosis has been implicated in both diabetes and atherosclerosis. Apoptosis can be induced through activation of the death receptors TNF receptor 1 (TNFR-1), TRAIL receptor 2 (TRAILR-2) and Fas. Soluble forms of these receptors are found in plasma. The objective of this study was to determine if soluble death receptors are markers of receptor-activat
This thesis is a phenomenological investigation into the differences and similarities between language as speech and language as a technique. Speech is the practice of producing and understanding utterances. A technique is the organizing mechanism of speech, the structure that gives it a regular form. While speech is heavily dependent on context and interpretation, a technique is unaffected by theThis thesis is a phenomenological investigation into the differences and similarities between language as speech and language as a technique. Speech is the practice of producing and understanding utterances. A technique is the organizing mechanism of speech, the structure that gives it a regular form. While speech is heavily dependent on context and interpretation, a technique is unaffected by the
To identify novel coding association signals and facilitate characterization of mechanisms influencing glycemic traits and type 2 diabetes risk, we analyzed 109,215 variants derived from exome array genotyping together with an additional 390,225 variants from exome sequence in up to 39,339 normoglycemic individuals from five ancestry groups. We identified a novel association between the coding var
Objective: To investigate the relationship between meniscus magnetic resonance (MR) relaxation parameters and meniscus degradation through quantitative imaging of ex vivo posterior horns of menisci from subjects with and without knee osteoarthritis (OA). Design: We sampled medial and lateral menisci from ten medial compartment knee OA patients (mean age 63 years) undergoing total knee replacement
In an effort to improve our understanding of the etiology and treatment of disorders involving symptoms of anxiety and depression, researchers have set out to identify psychological traits that may leave an individual vulnerable to experiencing intense negative emotional reactions. Included among these vulnerabilities are a person’s ability to tolerate negative emotional states (Distress Tolerance
Failures due to instability phenomena will happen suddenly and can cause the whole structure to collapse. It’s therefore in the engineer’s best interest to have a good knowledge about these phenomena. One example of instability phenomena is column buckling, which is the main focus of this thesis. The main cases that are being evaluated have a single brace in the middle of a timber column with hi
Arbetstagarskyddet vid verksamhetsöverlåtelser regleras inom Europeiska unionen (EU) av Rådets direktiv 2001/23/EG av den 12 mars 2001 om till-närmning av medlemsstaternas lagstiftning om skydd för arbetstagares rättig-heter vid överlåtelse av företag, verksamheter eller delar av företag eller verk-samheter (överlåtelsedirektivet). I svensk rätt har reglerna implementerats ge-nom ändringar i lag (The protection of employees in the case of business transfers is regulated within the European Union (EU) by Council Directive 2001/23/EC of 12 March 2001 on the approximation of the laws of the Member States relating to the safeguarding of employees’ rights in the event of the transfer of under-takings, businesses or parts of undertakings or businesses (Transfer of Un-dertakings directive). In Sw
200212. D€. schedule syllabus Doctoral School Agenda 2030 Digital Monies for a Sustainable Future The syllabus is preliminary and subject to changes till the course’s start. # Session Required readings Session focus Module 1: Setting the stage 1 Money today, theory and practice April 20, 13.00-16.00 Anders Ögren, Ester Barinaga, Paul Stankovski & Christian Gehrmann Readings: • Werner, R.2014. Can
https://www.sustainability.lu.se/sites/sustainability.lu.se/files/200212._deu._schedule_syllabus.pdf - 2026-06-22
200224. D€. schedule syllabus Doctoral School Agenda 2030 Digital Monies for a Sustainable Future The syllabus is preliminary and subject to changes till the course’s start. # Session Required readings Session focus Module 1: Setting the stage 1 Money today, theory and practice April 20, 13.00-16.00 Anders Ögren, Ester Barinaga, Paul Stankovski & Christian Gehrmann Readings: • Werner, R.2014. Can
https://www.sustainability.lu.se/sites/sustainability.lu.se/files/200224._deu._schedule_syllabus.pdf - 2026-06-22
