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BACKGROUND: Tofacitinib is a Janus kinase inhibitor for the treatment of ulcerative colitis (UC). Prospective real-world data are scarce.OBJECTIVES: To collect data on clinical outcomes, including health-related quality of life (HRQoL) and fatigue during treatment with tofacitinib.DESIGN: This is a prospective observational multicentre study in Sweden. In this analysis, outcomes at weeks 2, 8 and

Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei

A shift in new venture creation can be observed from purely profit-oriented models to alternatives attempting to also answer social and environmental needs. Because of their nature, these alternatives face issues regarding their integration in traditional financial and business spheres. Shared Value Creation is a framework that attempts to analyse these ventures and those challenges. Blockchain te

Moraxella catarrhalis is a human-specific commensal of the respiratory tract and an opportunistic pathogen. It is one of the leading cause of otitis media in children and of acute exacerbations in patients with chronic obstructive pulmonary disease, resulting in significant morbidity and economic burden. Vaccines and new immunotherapeutic strategies to treat this emerging pathogen are needed. Comp

Streptococcus pyogenes is an exclusively human pathogen that can provoke mild skin and throat infections but can also cause fatal septicemia. This gram-positive bacterium has developed several strategies to evade the human immune system, enabling S. pyogenes to survive in the host. These strategies include recruiting several human plasma proteins, such as the complement inhibitor, C4b-binding prot

Microsoft Word - Eligibility form - new version Eligibility form This eligibility form is compulsory to fill out for any exchange student who wishes to apply for courses with prerequisites at the Lund University School of Economics and Management (LUSEM) and the Faculty of Science, or courses in Engineering at the Faculty of Engineering (LTH). Required information: Name: __________________________

https://www.science.lu.se/sites/science.lu.se/files/2025-03/Eligibility_Form_LUSEM_LTH_N_2025.pdf - 2026-06-06

Armlängdsprincipen kan betraktas som en av de mest centrala principerna inom den internationella beskattningsrätten. I OECD:s modellavtal, som ligger till grund för utformningen av bilaterala dubbelbeskattningsavtal, stadgas armlängdsprincipen i artikel 9, den regel som tillåter korrigering av ett företags vinst när interna transaktioner prissatts på ett sätt som inte är armlängdsmässigt. SamtidigThe ALP can be considered one of the most significant principles within international taxation law. It is regulated under article 9 of the OECD MTC, which acts as a model for developing new bilateral tax treaties. According to article 9, the profit of an enterprise may be adjusted if the enterprise has been involved in transactions with an associated enterprise on conditions that are not of an arm

Eutrofiering det oönskade fenomenet av hög näringstillförsel i ett akvatiskt system, är för det mesta ett resultat av mänsklig påverkan: industriellt och urbant avloppsvatten, avrinning av gödningsmedel från odlad mark, och förbränning av fossila bränslen. Studien av de främsta faktorerna som bidrar till eutrofiering (t. ex. variationer i kvävets kretslopp), är viktigt för förståelsen av dess negaEutrophication, the undesired phenomenon of high nutrient loads in an aquatic system, is mostly caused by human impact: industrial and urban waste water discharge, run-off of fertilizers from agricultural use, and combustion of fuels. The study of eutrophications' main participants such as the nitrogen cycle, are necessary to prevent it. Environmental parameters have an impact onto the effecti

For cities growing in conditions of extreme heat and aridity, adapting their building stock to reflect these environmental challenges demands a social as well as technical shift. Aqaba in southern Jordan is embarking on this process. Extremely poor building thermal performance coupled with a lack of public understanding of basic energy principles is contributing to social and economic stress in Aq

The role of cholesterol differs in the two compartments of the testis. In the interstitial tissue, cholesterol is necessary for the synthesis of testosterone, whereas in the seminiferous tubules, membrane cholesterol content in developing germ cells will influence the gametes' fertility. Here we evaluate the hormone-sensitive lipase (HSL) modulation of the cholesterol metabolism in each compartmen

Popular Abstract in English In our current world, the exponential growth in demand for smaller and faster devices leads to the fact that we will eventually face the problem that traditional semiconductor technologies will reach their limitation in terms of size and speed. Humanity's consciousness to tackle the global ecological issues in the next decade, will demand the substitution of all non-reuThe work presented in this thesis addresses the investigation of the electronic, magnetic, and structural properties of late transition metal complexes supported on various surfaces. The research is aimed at studying the interaction between the molecules and the support, together with the intermolecular interaction. This knowledge is essential e.g. for the development of organic molecule-based dev

Climate change and environmental awareness have been a focus topic in the past years due to the increase of greenhouse emissions in the atmosphere. A significant part of the problem is the greenhouse gas emissions caused by the construction industry, whether in the early stages of construction or over the life of a building. In order to reduce human impact, several actors in the building and const

”ÅTERHÄMTNINGSSKOLA” för dig med egen erfarenhet att leva med psykisk ohälsa. ”Att bli den bästa versionen av mig själv” (Citat: av P, Deegan, översatt från engelska till svenska ) Vi träffas tisdagar och torsdagar 13–16 på Mötesplatsen Vänkretsen Rundelsgatan 14 A Kurserna består av två block. Vi bjuder på fika Återhämtning är en individuell process och handlar om att gå från psykisk ohälsa till

https://www.cepi.lu.se/sites/cepi.lu.se/files/2023-11/%C3%85terh%C3%A4mtningsskola%20i%20Malm%C3%B6_Planering%20och%20utv%C3%A4rdering_Annika%20Larsson%20Annika%20Wihlborg.pdf - 2026-06-06