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Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe
Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i
Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that
This thesis is about autistic women. It is about how we, as a society, construct and perceive normality and motherhood as a normative ideal for women. It is also about a dis/ability that often goes unnoticed since autism is not defined by any visible markers. Rather, autism is categorized by behaviour considered atypical through the medical gaze. How to make visible the invisible, the in-between
Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3
Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi
China’s financial actions along the BRI network has sparked a lot of controversies, one of these being the alleged usage of Debt Trap Diplomacy (DTD) in order to gain access to resources through debt relief that they otherwise would not be able to reach through traditional means. DTD practices can be considered part of the International Political Economy’s ‘blind spots’ due to their complexity and
Beskrivning ämne 2 kopia Ämne 2 musik, Estetiska fördjupningskurser Innehåll Totalt omfattar de estetiska fördjupningskurserna 90hp och läses vid Musikhögskolan i Malmö. Varje kurs omfattar 30 eller 60hp. Sammanlagt kan tre kurser väljas, alternativt två om en av kurserna är Musikproduktion 60hp, Arrangering/ komposition 60hp, Körledning/ kördirigering 60hp eller Rytmik 60hp. Om man önskar göra u
https://www.mhm.lu.se/sites/mhm.lu.se/files/beskrivning_amne_2_kopia.pdf - 2026-06-19
The aim of this doctoral dissertation is to explore and describe the relationship and interaction between musicians and their instruments. In order to achieve a high level of detail, a certain instrument is in focus: the simple-system flute. Although primarily developed as a product of 19th- century Western art music, this instrument has since become established in other genres and traditions. Emp
The aim of this doctoral dissertation is to explore and describe the relationship and interaction between musicians and their instruments. In order to achieve a high level of detail, a certain instrument is in focus: the simple-system flute. Although primarily developed as a product of 19th-century Western art music, this instrument has since become established in other genres and traditions.EmpirThe aim of this doctoral dissertation is to explore and describe the relationship and interaction between musicians and their instruments. In order to achieve a high level of detail, a certain instrument is in focus: the simple-system flute. Although primarily developed as a product of 19th-century Western art music, this instrument has since become established in other genres and traditions.Empir
How to operate the alarm at KHM2 Alarm is ON Alarm is OFF When there is a red LED light on the alarm it is active (alarm is on) and you need to deactivate it to be able to open the door. Turn off (deactivate) the alarm by: 1. Press # 2. Hold up your card to the reader (blue LED light) until you hear a beep 3. Press you
https://www.khm.lu.se/en/sites/khm.lu.se.en/files/khm2_info_combined_eng_november2019.pdf - 2026-06-19
How do we describe a location on earth? How do we describe a location on Earth? Geodetic reference system http://www.google.co.uk/imgres?imgurl=http://4.bp.blogspot.com/-v2sej--Hf9Y/TbGzN0FeN7I/AAAAAAAAAQ0/dXTA6XAP7Nk/s1600/earth-3d.gif&imgrefurl=http://ods-destruction-carbon-credits.blogspot.com/2011/04/happy-earth-day-from-remtec.html&usg=__1-2G0CU8X0-43x3j7NY4oN1vYS8=&h=1024&w=1024&sz=266&hl=en
https://www.nateko.lu.se/sites/nateko.lu.se/files/field2.pdf - 2026-06-19
Owing to recent developments in CMOS technology, it is now possible to exploit tomographic microscopy at third-generation synchrotron facilities with unprecedented speeds. Despite this rapid technical progress, one crucial limitation for the investigation of realistic dynamic systems has remained: A generally short total acquisition time at high frame rates due to the limited internal memory of av
