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High-speed biomarker identification utilizing porous silicon nanovial arrays and MALDI-TOF mass spectrometry

Speed and accuracy are crucial prerequisites in the application of proteomic methods to clinical medicine. We describe a microfluidic-based nanovial array for rapid proteolytic processing linked to MALDI-TOF MS. This microscale format consumes only minute amounts of sample, and it is compatible with rapid bioanalytical protocols and high-sensitivity readouts. Arrays of vials (300 mu m in diameter

Increased level of soluble HLA class I antigens in systemic lupus erythematosus: correlation with anti-DNA antibodies and leukopenia

The concentration of soluble HLA class I (sHLA-I) was measured by ELISA in serum samples from 30 well-characterised SLE patients at high and low disease activity states and from 100 healthy controls. HLA-A allotypes in the patients were analysed by a PCR-based typing technique. A higher level of sHLA-I was found in SLE patient sera both at high and low disease activity than in controls (P< 0.001).

Eyes Wide Shut: Seeing the Safety Management System as a State

Airlines are required to manage safety by implementing a Safety Management System (SMS). These systems are built on experience with quality management and seek to provide a structure for organisations to manage the risks presented by and to their individual operations. Safety is presented by the SMS as a ‘state of being’ arrived after following risk management to a level as low as reasonably pract

Tvåundantaget i LAS och dess relation till kollektivavtal

I Sverige kom det första undantaget från turordningsreglerna 1994 med syftet att upprätthålla balansen mellan arbetstagarnas trygghet och verksamheternas behov av flexibilitet. Sedan 2001 är undantaget i turordningsreglerna begränsat till två personer och gäller för företag med högst tio anställda. År 2020 är tvåundantaget återigen uppe för diskussion om ändring i och med betänkandet SOU 2020:30, In Sweden the first exception concerning turn rules was accepted in 1994 with the purpose to maintain the balance between employment protection and the companies need for flexibility. Since 2001 the exception concerning turn rules is limited to two employees for organisations with at most ten employees. In the year of 2020 the exception within the turn rules is up for discussion once again hence t

Evaluation of Novel Quality Control Methods for Wheat Flour

The quality of a flour can vary greatly depending on the wheat variety and on the conditions while growing the wheat. Currently, the quality is mainly assessed by test baking the flour to observe the volume of the final product. The aim of this study was to investigate if three instruments (Alveolab, Mixolab and Rheo F4) analyzing rheological behaviours connected to dough preparation and baking pr

Sjukhuskuratorns förutsättningar till interprofessionell samverkan i en medicinsk miljö - En kvantitativ studie om hur de mer medicinskt inriktade yrkesgrupperna läkare, sjuksköterskor och undersköterskor uppfattar förutsättningarna till interprofessionell samverkan med sjukhuskuratorn

Abstract Authors: Jonas Johansson and Jimmy Dahlqvist Titel: Hospital social worker's opportunities for inter-professional collaboration in a medical setting [translated title]. Supervisor: Stig Linde In health care there exists a medical culture that is based on proven experience and science. Hospitals are dominated by personnel who have a medical background and thus have a medical focus in

LED's Buy Greener: Shedding Light on Sustainable Procurement

In last decade, the lighting industry significantly changed with the development of light emitting diodes (LEDs) and their corresponding penetration of the market. The new technology increases energy efficiency and longevity compared to other types of lamps. As a result, LEDs can improve the sustainability performance of cities and towns, contributing to the mitigation of climate change and cuttin

Statelessness and the ability to receive a residence permit based on impediments to enforcement

Being stateless, roughly means being without a citizenship of any nation. This is the definition of being stateless in legal terms, called de jure statelessness. There is also statelessness that entails being without the efficient protection of one’s nation, called de facto statelessness. Two groups of stateless migrants that correspond to these definitions are Bidoons from Kuwait and Palestinians

The Young Creatives: A Value-Based Approach to Cultural Entrepreneurship in Yogyakarta, Indonesia

The creative economy (CE) has recently been at the forefront of Indonesia’s development agenda. By harnessing human creativity and cultural resources, there is considerable potential for CE and the creative and cultural industries to contribute to economic growth and generate employment opportunities for the country’s expanding working-age population. However, the virtues of CE have largely been e

Service recovery 2.0

Syfte: Uppsatsens syfte är att analysera och förstå service recovery-processen i ett serviceföretag med en komplex verksamhet genom att fokusera på klagomål som framförts i sociala medier. Metod: Undersökningen bygger på en kvalitativ fallstudie av ett företag i kryssningsbranschen. Inledningsvis genomfördes en mindre observationsstudie som åtföljdes av ett antal semistrukturerade intervjuer. DesTitle: Service recovery 2.0 - social media complaints in complex service businesses Purpose: The purpose of this thesis is to examine the service recovery process in a complex service business while focussing on complaints delivered via social media channels. Approach: After an initial literature review and a small observational study, a qualitative study was conducted based on semi structured i

A empirical study of one-day risk prognosis models, using Value-at-Risk and three different GARCH-models

This thesis assess three different conditional variance models from the GARCH family - GARCH(1,1), EGARCH(1,1) and GJR-GARCH(1,1) - and their accuracy in making one-day forecasts together with Value at Risk. The study is made on the daily returns of the OMX Stockholm 30 index between 2002-01-01 and 2010- 12-31. A five year in-sample set was used to estimate the model parameters and to make one-day

Diskurser i referenssamtalet: En diskurspsykologisk studie

This Master's thesis aims to investigate the reference interview using the discourse analytical method discourse psychology. The reference interview has been studied thoroughly, and its importance has been proven repeatedly within the field of Library and Information Science (LIS). However, it has never been studied from a discourse analytical point of view before. The material for our study

Den interaktiva IR-forskningens genomslag i söktjänsterna på webben

The theoretical focus in this master is information retrieval (IR), and especially the part of IR that includes interactivity. This research is by some researchers called IIR. Our principal aim was to examine if search engines on the WWW are taking advantage of research results from IIR research. A way to do this is to look at the application of special features, in this case query expansion (QE)

Människohandel - Ett nutida slaveri. Svenska myndigheters lokala arbete med ett globalt problem

Human trafficking is the world’s third largest organized crime after the illegal trade in arms and drugs. It is a growing problem in our increasingly globalized world and people are daily transported between countries to be exploited for different purposes. Not even Sweden is spared from this cynical business, although we may not hear much about it. The aim of this study was to investigate how Swe

Att använda resurserna rätt… Primärvårdskuratorers handlingsutrymme vid sjukskrivning av patienter med psykisk ohälsa

The aim of this study was to explore how primary care social workers discuss their professional role and discretion in relation to considerations of sick leave for patients with mental illness, thereby deepening the understanding for how consultation and informal decision processes manifest between social workers and doctors working within the same organisation. Qualitative semi-structured intervi

Testbed-Mentality: The government of a testbed for sharing in Sege Park in Malmö

This thesis investigates how urban experimentation is governed in the new development district in Sege park in Malmö. Together with with private developers and a local NGO the municipality test and experiment with solutions for how the sharing economy can contribute to reduce the future resident’s climate impact and living costs. By using the theoretical lens of governmentality this thesis focusse

Ett huvudcykelstråk i Malmö - Cykelns roll i planeringen

Sveriges transportpolitiska mål belyser vikten av hållbara resor. En nationell cykelstrategi är framtagen som en del i att uppnå det övergripande målet. Cykelplanering måste ske på ett tidigt stadium och vara med under hela planprocessen och bilen måste komma i andra hand i stadsplaneringen. En bra grund i planeringen är att försöka beskriva funktionen i ett differentierat cykelnät, en uppdelning The Swedish transport policy objectives show the importance of sustainable transportation. A national bicycle strategy is developed to help achieve the general objective regarding transportation. The bicycle must be included in the whole process with the car coming in second hand. Basic recommendations for cities are to arrange their bicycle network in at least two parts, a main cycle network and

En Pie de Marcha - Commoning in Times of Crisis

The continuous and on-going enclosure of the commons has been identified as critical for the expansion of capitalism, through processes of dispossession, expropriation and commodification. In the light of the rapid erosion of our cultural and environmental common pool resources, the concept of the commons is increasingly gaining interest, since it presents new political and cultural perspectives a

Logistik vid förtätning

Förtätning och byggande i urbana miljöer innebär stora utmaningar för alla inblandade parter, stadens invånare, verksamheter och besökare. Låg effektivitet- och produktivitetsutveckling i byggbranschen, tillsammans med ökade miljökrav är ett par av de främsta utmaningarna. Krav på effektiv ytanvändning förutsätter en välfungerande, effektiv logistik och materialhantering, med minimal påverkan på dDensification of cities and construction in urban environments poses major challenges for all parties involved, the city's residents, businesses and visitors. Low efficiency and productivity development in the construction industry, together with increased environmental requirements are a few of the main challenges. Requirements for efficient use of surface demands efficient logistics and mate