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INTRODUCTION: Blood-based biomarkers have demonstrated high accuracy for identifying Alzheimer's disease (AD) pathology. However, the lack of representative cohorts creates a knowledge gap regarding their real-world applicability. We examined the influence of ethnicity on the diagnostic accuracy of plasma tau phosphorylated at threonine 217 (p-tau217) in identifying AD. METHODS: A total of 1170 mi
Introduction As care and rehabilitation poststroke are increasingly moving into persons’ home environment, the importance of support from social networks in self-management and rehabilitation has emerged as an important topic for research and practice. While there are instruments used to assess social support and collective efficacy, a clearer scope of the availability and quality of these instrum
Background: Japan lacks efficient assessment tools for occupational balance (OB) in people with mental illness (MI). Aims/objectives: We investigated the test–retest reliability and construct validity of a Japanese version of the Satisfaction with Daily Occupations and Occupational Balance (SDO-OB-J) for people with MI. Methods: SDO-OB-J interviews were conducted twice at a 2-week interval. Result
BACKGROUND: The Leiden group and the Assessment of Spondyloarthritis International Society (ASAS)-MRI study group have proposed definitions for structural (SL) and active (AL) lesions typical for axial spondyloarthritis (axSpA) on MRI of the sacroiliac joints (MRI-SIJ).OBJECTIVES: To analyse the predictive validity of proposed SL and AL MRI-SIJ definitions in early axSpA and compare proposed AL wi
Background: Posttraumatic stress disorder (PTSD) and substance use disorders (SUD) frequently co-occur in youth. Integrated, trauma-focused treatments are recommended, but evidence in youth is limited and the dynamics of symptom change are poorly understood.Objectives: We investigated within-treatment changes in PTSD and substance use, and their temporal sequencing, in a randomised controlled tria
Background: Stereotactic body radiotherapy (SBRT) is an established treatment for previously unirradiated spinal metastases; however, the literature is limited with respect to SBRT as a re-irradiation salvage therapy. We performed a systematic review and meta-analysis as basis for joint ESTRO-ISRS clinical practice recommendations of salvage SBRT for spinal metastases. Methods: A systematic review
BACKGROUND AND OBJECTIVES: Iron deficiency anaemia is common in patients recovering from major surgery and is associated with poorer post-operative outcomes. We designed a randomized controlled trial treating post-operative anaemia with iron therapy to observe the influence on post-operative recovery.MATERIALS AND METHODS: Anaemic patients (haemoglobin [Hb] < 120 g/L for women, Hb < 130 g/L for me
Urbanization is driving cities to grow, often through urban densification. Utilising computer-based simulations executed over 3D representations of the city is imperative in addressing the challenges posed by implementing sustainable urban densifications; like ensuring adequate access to daylight and limiting noise pollution. However, since these simulations are usually resource-intensive, timecon
Herein, we present a case of severe immune-related adverse events (irAEs), myocarditis with myositis, and myasthenia gravis overlap syndrome (IM3OS) in a patient receiving an immune checkpoint inhibitor (ICI), as adjuvant therapy after surgery for muscle-invasive bladder cancer. An 80-year-old woman who had undergone a total cystectomy for bladder cancer presented with ptosis, diplopia, and paraly
Digital technologies in welfare organizations frequently generate gaps, ambiguities, and misalignments that require professional intervention. Yet prior research has tended to portray frontline workers mainly as resistant or adaptive actors, leaving under-examined their active contributions to sustaining broader digital infrastructures. This article introduces the concept of digital compensatory wDigital technologies in welfare organizations frequently generate gaps, ambiguities, andmisalignments that require professional intervention. Yet prior research has tended to portrayfrontline workers mainly as resistant or adaptive actors, leaving under-examined their activecontributions to sustaining broader digital infrastructures. This article introduces the concept ofdigital compensatory work
Women constitute a minority among patients in forensic psychiatric care, which aims to improve the patients’ health while ensuring safety for patients, caregivers, and society. Participation in forensic psychiatric care can be complex; its definition depends on the context and perspective and is influenced by several factors. This study examined the perceptions of female patients and caregivers re
(Microsoft Word - Kursutv\344rdering GEOP04 vt 2016) Kursutvärdering GEOP04 vt 2016 På kursen deltog 22 studenter. Av dessa har 9, dvs 41%, lämnat en kursvärdering. Frågan ”Hur anser du att kursens mål är uppfyllda på en skala från 1 (ej uppfyllda) till 5 (väl uppfyllda)” utföll enligt nedan: • 1 0 studenter 0% • 2 1 student 11,1% • 3 2 studenter 22,2% • 4 6 studenter 66,7% • 5 0 studenter 0% Slut
https://www.geologi.lu.se/sites/geologi.lu.se/files/geop04_kursutvardering_vt_2016.pdf - 2026-07-02
Duchenne muscular dystrophy (DMD) is the most common childhood myopathy, characterized by muscle loss and cardiorespiratory failure. While the genetic basis of DMD is well established, secondary mechanisms associated with dystrophic pathophysiology are not fully clarified yet. In order to obtain new insights into the molecular mechanisms of muscle dystrophy during earlier stages of the disease, we
Background: Access to contraception can be a transformational intervention towards advancement of education, health, and freedom of choice. Countries have committed to improving access to contraception enshrined in the sustainable development goals (SDGs), indicator 3.7.1. Our study seeks to investigate the level of inequality in current use of modern contraception and unmet need for contraception
Social, ecological, and cultural impacts associated with the U.S. military in Hawaii are egregious. However, due to the historical oppressions and injustices to Hawaiians, the U.S. military maintains their hegemony by wielding a disproportionate decisive political and economic power. This study aims to explore perceptions of Native Hawaiian and non-native activists regarding the military impacts a
Many companies have introduced initiatives to achieve environmental sustainability and improve the wellbeing of the producers. This is the goal of the Era of We – an online platform that strives to disrupt the current market practices, promote environmentally sound coffee production and empower farmers. This thesis explores the perceived power dynamics between different stakeholders and how are th
Syftet med uppsatsen är att undersöka hur amerikanska påståenden kring Irakiska massförstörelsevapen användes som övertalningsmedel innan och omedelbart efter invasionen av Irak 2003. Detta görs via en kvalitativ innehållsanalys. Analysen utgår från Jowett och O`Donnells teoretiska ramverk på tio punkter för analys av propaganda. Dessa operationaliseras och appliceras på källmaterialet. Källmateri
The substantial growth of private health insurance in 21st century Sweden has sparked debates about its potential effect on waiting times within the public health care system. Some argue that individuals with private health insurance are prioritized in the waiting list for health care, potentially leading to longer waiting times for those without private coverage. Conversely, others argue that pri
The one-dimensional inverse scattering problem for inhomogeneous lossy media is considered. The model problem involves electromagnetic wave propagation in a medium of unknown thickness with spatially varying conductivity and permittivity. Two inversion algorithms are developed in the time domain using data obtained from normally incident plane waves. These algorithms utilize reflection data from b
In 2014 the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy (RAV) conducted a review and analysis of the state of knowledge on the duration of follow-up after exposure to human immunodeficiency virus (HIV). Up until then a follow-up of 12 weeks after exposure had been recommended, but improved tests and new information on early diagnosis motivated a re-evaluati
