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The raison d’être of the humanities is widely held to reside in its unique ability to generate critical thinking and critical thinkers. But what is “critical thinking?” Is it a generalized mode of reasoning or a form of political critique? How does it relate to discipline-specific practices of scholarly pursuit? How does it relate to discourses of “post-truth” and “alternative facts”? How is it be
Background: Unresectable disease is sometimes diagnosed during surgery in patients with pancreatic ductal adenocarcinoma (PDAC). This study aimed to identify preoperative risk factors for metastatic disease diagnosed at surgical exploration and to investigate and compare survival in resected and non-resected patients. Methods: Patients were identified from the Swedish National Pancreatic and Peria
Background and purpose: The treatment of biochemical recurrence (BCR) after prostatectomy is challenging as the site of the recurrence is often undetectable. Our aim was to test a personalised treatment concept for BCR based on PSA kinetics during salvage radiotherapy (SRT) combined with prostate-specific membrane antigen positron emission tomography (PSMA-PET).Materials and methods: This phase II
This paper analyzes strategies that can be successfully pursued to implement measures to reduce car traffic in what has traditionally been a very car-centric planning praxis. Analytically, the paper use path dependency theory to provide an understanding of why certain types of measure are not implemented in cities on as widespread a basis as policy objectives may require, and to understand how tra
Purpose: Varicocele is a common problem among infertile men. Varicocele repair (VR) is frequently performed to improve semen parameters and the chances of pregnancy. However, there is a lack of consensus about the diagnosis, indications for VR and its outcomes. The aim of this study was to explore global practice patterns on the management of varicocele in the context of male infertility. Material
Context. Hot subdwarfs experienced strong mass loss on the red giant branch (RGB) and are now hot and small He-burning objects. These stars constitute excellent opportunities for addressing the question of the evolution of exoplanetary systems directly after the RGB phase of evolution.Aims. In this project we aim to perform a transit survey in all available light curves of hot subdwarfs from space
A metaphyseal bone defect due to infection, tumor or fracture leads to loss of cancellous and cortical bone. An animal model separating the cancellous and cortical healing was used with a combination of a macroporous gelatin-calcium sulphate-hydroxyapatite (Gel-CaS-HA) biomaterial as a cancellous defect filler, and a thin collagen membrane (CM) guiding cortical bone regeneration. The membrane was
There is a great unmet clinical need to identify patients with thin primary cutaneous melanomas (T1, Breslow thickness ≤ 1 mm) who have a high risk for tumour recurrence and death from melanoma. Kin of IRRE-like protein 1 (KIRREL/NEPH1) is expressed in podocytes and involved in glomerular filtration. Screening in the Human Protein Atlas portal revealed a particularly high expression of KIRREL in m
Objectives: Successful gestational weight gain (GWG) restriction programs for obese (Body Mass Index (BMI) ≥ 30 kg/m2) pregnant women, have not, so far, shown convincing effects on infant's weight development. An intervention starting during the pregnancy might be too late and a pre-conceptional life style change may be preferable. Thus, the aim of this study was to follow children born to mothers
Purpose: A cost minimisation analysis compares the costs of different interventions’ to ascertain the least expensive over time. We compared different prostate targeted drug treatments with TURP to identify the optimal cost saving duration of a medical therapy for symptomatic benign prostatic enlargement (BPE). Methods: The Evolution registry is a prospective, multicentre registry, conducted by th
OBJECTIVES: To estimate the incidence of non-vertebral fractures in ankylosing spondylitis (AS) compared with the general population. METHODS: Nationwide register-based cohort study including patients with AS (n=11 611, 65% men, mean age 48 years), and matched general population controls (n=58 050). Five prespecified fracture outcomes: (1) non-vertebral; (2) fracture of the proximal humerus, dista
Background: Participatory research has been described to improve the relevance of research findings for the society in terms of quality of healthcare services and other public benefits. Nevertheless, there is limited guidance on how to conduct participatory research, and especially in relation to persons living in residential care facilities. To make the voices of this group heard, we therefore ta
Introduction: Decades of nuclear activities have polluted marine environments with transuranium actinides. Background: Brown algae have frequently been used as marine bioindicators of radioactivity, but current literature describing the sequential separation and determination of Pu and Am from brown algae matrices is sparse, and does not make use of recent extraction chromatographic resins such
Lantbruket står inför stora förändringar till följd av en snabb ökning av den globala befolkningsmängden och klimatförändringar som skapar stor press på värdekedjan för matproduktion. Användningen av teknologier för precisionsodling (PA) har visat sig ha fördelar som kan vara en del av lösningen för dessa framtida utmaningar. Trots detta råder det inte konsensus inom forskarkåren om vilka aspekterThe agricultural industry is going through immense changes due to the rapid growth of the global population and climate change, creating increased pressure on the food supply chain. The use of precision agriculture (PA) technologies have shown benefits that could help solve these challenges. Despite this, there is no consensus among researchers on what aspects affect the adoption of PA technology
This master’s thesis investigates sustainability management within a fashion company and how a company could use the sustainability management tool the Higg Index 2.0 Brand and Retail Module to work towards its prioritised UN Sustainable Development Goals (SDGs). It is a comparative review of the two frameworks, the Index and the SDGs, from a life cycle analysis perspective. It also includes a cas
The Lisbon Treaty has made Policy Coherence for Development a legal obligation for the EU, thus the Union’s has a clear institutionalised commitment to makes sure that non-aid policies are not undermining the objectives in the development policy. EU’s energy policy with the 10% target of biofuels in the transport sector have been a point of great debate. Biofuels have been contested both within th
This thesis examines the advocacy strategies employed by civil society organisations (CSOs) in Cambodia, focusing on land rights and women’s rights within the constraints of a shrinking civic space. The study aims to understand how CSOs mobilise resources and adapt their strategies to address human rights issues in an authoritarian context. Using postcolonial theory, resource mobilisation theory,
This qualitative research explores the measures of civil society organisations (CSOs) in the labour market integration of female refugees. For this, expert interviews with five 'best practice' CSOs in Germany were conducted to highlight the measures the initiatives take in light of the obstacles they face in their work. The results show that both tangible and intangible measures are taken,
