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BACKGROUND: Shared decision-making (SDM) between clinicians and patients is one of the pillars of the modern patient-centric philosophy of care. This study aims to explore SDM in the discipline of trauma and emergency surgery, investigating its interpretation as well as the barriers and facilitators for its implementation among surgeons.METHODS: Grounding on the literature on the topics of the und
Background: Primary healthcare providers are increasingly challenged in supporting patients with psychosocial needs. Arts on Prescription (AoP) has been shown to improve primary healthcare patients’ mental health wellbeing. The aim of the current study is to understand the psychosocial effect of participating in an Arts on Prescription programme. Methods: A total of 112 primary healthcare patients
Background: Lung injury in COVID-19 is characterized by neutrophil invasion and the release of neutrophil extracellular traps (NETs). An aberrant NET formation may induce local inflammation and increase sputum viscosity. Inhalation of DNase I (dornase alfa) is a treatment option that degrades NETs in the airways. Previous case series have indicated positive clinical effects of inhaled dornase alfa
District heating and cooling is a simple but powerful technology that could contribute to decarbonising Europe's heating and cooling supply. However, its current overall penetration is minor. Furthermore, future systems could adopt different configurations with various settings of temperature levels or production location. This thesis has aimed to improve existing tools to evaluate district heatin
Casein micelles are key structures in milk, influencing stability, nutritional properties, and functionality. Their hierarchical architecture, which is dynamic and responsive to environmental conditions, plays a crucial role in dairy processing. Understanding the structural and dynamic properties of casein micelles is essential for optimizing dairy products and processing techniques. This study pr
Purpose: Radiation therapy (RT) causes tissue damage and inflammation. Because cytokines play a key role in such processes, their expression levels can be an indicator of cell and tissue toxicity. This critical review aims to explore whether levels of circulating inflammatory biomarkers in peripheral blood are associated with proton- or photon-based therapy in the pelvic area and how these levels
Educational development initiatives in the form of short-lived, isolated pedagogical courses may at best change the thinking and practice of a few pioneers, and then perhaps only temporarily. It is only possible to successfully address the need that such initiatives are intended to meet if the impact is lasting and effects a cultural change locally at the university. In this study, we look beyond
Robots, which were seen as gimmicks in science fiction stories until not so long ago, have already crossed into reality. Thanks to the ever-growing autonomy of robots and ever-expanding variety of roles assigned to them, they are becoming more integrated into the ordinary course of everyday life. With the advent of social robots that can engage human beings on personal levels, for the first time,
The Middle Danube (Carpathian) Basin is considered to encompass some of the thickest and most complete records of aeolian dust deposition in Europe, covering the last two glacial–interglacial cycles. In this study, independent, published chronologies based on absolute dating methods were compiled for 34 loess-palaeosol sequences and modelled using Bayesian statistics. Mass accumulation rates (MARs
The book’s aim is to systematize normative assessments of the Court of Justice of the European Union’s decision-making process, defining ‘normative’ as an evaluation based on openly acknowledged, theoretically informed standards that take into account the institutional reality of the Court. This is important because the stakes are very high: the Court is a very influential institution, and the mot
The major challenges faced by confectionery supply chain are lack of information, traceability, managing the ownership of goods across supply chains, inability to track vendors in real-time. Blockchain and Internet of Things (IoT) in Industry 4.0 era help organisations to overcome these challenges by guaranteeing authentic information, real-time visibility, and transparency across the supply chain
UNLABELLED: Herein we present a system to obtain fibers from clickable elastin-like recombinamers (ELRs) that crosslink in situ during the electrospinning process itself, with no need for any further treatment to stabilize them. These ELR-click fibers are completely stable under in vitro conditions. A wrinkled fiber morphology is obtained. In addition to a random fiber orientation, oriented fibers
Large language models can transform individuals’ mental health descriptions into scores that correlate with rating scales approaching theoretical upper limits. However, such analyses have combined word- and text responses with little known about their differences. We develop response formats ranging from closed-ended to open-ended: (a) select words from lists, write (b) descriptive words, (c) phra
If one were to study Management Consultancy, they could be spoilt for choices on what to research on. Bombarded by several images of imperviousness, merky business practices , shady deals, compromise, self service, competitive morality and many other forms of euphemisms, the researchers, would see these notions, appear loud and resplendent, especially when, ‘seen through’ client consultant relatio
The use of CFD-models as an engineering tool for fire based analytical design of buildings has increased over the last few years. The reason for this is partly that the legislation allows for analytical dimensioning but also because the legislation demands a high degree of verification for the analytical dimensioning. The biggest reason is, however, that the computer power has increased and reache
This thesis investigates how the experience of founding a youth-led social-innovation project can enhance young people’s agency for sustainable development, through a qualitative single-case study of Ashoka Belgium’s 2023 Youth for Change (Y4C) programme. Grounded in a social-constructivist, abductive logic, the study uses semi-structured interviews and mobilises three strands of scholarship—Socia
This thesis examines how outnovation is enacted within design entrepreneurship, with fashion design entrepreneurship as the empirical context. It analyses how value formed through design practice may contribute to sustainable competitive advantage. Understood as an alternative innovation logic centred on authenticity, nostalgia, simplicity, and sustainability, outnovation offers a counterpoint to
Despite the significant advances in cancer genomics, identifying all cancer drivers (CDs) remains a challenge. Most of the existing approaches rely heavily on mutational data, while emerging research has started to put focus on epigenetic regulation in cancer development. This is why the OriGENE model —a convolutional neural network (CNN) was developed to classify CDs based on H3K4me3 histone modi
Purpose: As greenwashing becomes an increasingly prevalent concern in the sustainability industry, the pressure of organizations to be perceived as credible is rising. One strategic approach to enhance perceived credibility is through collaboration with a non-governmental organization (NGO). This study aims to examine the impact of NGO–For-Profit co-branding on the brand attitude of both the for-
