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Definition: The Mbuluzi River runs through Swaziland and Mozambique into the Indian Ocean. Due to water shortage, population increase and growing industrial and agricultural sectors, high stress is being put on the water quality. The importance of keeping good water quality is accentuated by the fact that the River is shared between two countries and that it supports both capitals with drinking wa

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The International Criminal Tribunals for the Former Yugoslavia and for Rwanda symbolise the commitment of the international community to put an end to impunity and to reintroduce justice and due process where it has long been denied. With the addition of the Special Court for Sierra Leone and the International Criminal Court international criminal justice has developed into a permanent feature of

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Previous studies have shown increased cardiovascular mortality as late side effects in Hodgkin lymphoma (HL) patients. This study identifies stratifying risk factors for surveillance and defines concepts for a clinical feasible and noninvasive prospective protocol for intervention of cardiovascular side effects. HL patients diagnosed between 1965 and 1995 (n = 6.946) and their first-degree relativ

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Immunization of mice with type II collagen (CII) leads to collagen-induced arthritis (CIA), a model for rheumatoid arthritis. T cell recognition of CII is believed to be a critical step in CIA development. We have analyzed the T cell determinants on CII and the TCR used for their recognition, using twenty-nine T cell hybridomas derived from C3H.Q and DBA/1 mice immunized with rat CII. All hybridom

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An electron storage ring acts as an approximate point source in the far-infrared spectral region with a much greater intensity than provided by conventional black body radiators. Far-infrared synchrotron radiation is therefore suitable for high-resolution spectroscopic measurements of low-frequency vibrations for metastable molecules such as the intermolecular vibrational modes of hydrogen-bonded

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Inhibitors of the enzyme dipeptidyl peptidase IV (DPP IV) are of increasing interest to both diabetologists and the pharmaceutical industry alike, as they may become established as the next member of the oral antidiabetic class of therapeutic agents, designed to lower blood glucose and, possibly, prevent the progressive impairment of glucose metabolism in patients with impaired glucose tolerance a

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The “acidic mantle” of the skin surface has been related to several essential functions of the skin, although the origin of the acidity is still obscure. In this paper, we investigate how different transport processes can influence the local proton concentration inside a membrane consisting of oriented lipid bilayers. This system is chosen as a simple model of the extracellular lipids in the upper

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Quality of life (QoL) assessment in children with coagulation disorders is a relatively unstudied area. While hemophilia-specific questionnaires (such as Haemo-QoL) are available, no instrument for children with idiopathic thrombocytopenic purpura (ITP) has been validated yet. A disease-specific questionnaire for children with ITP was therefore developed (ITP-QoL) in three phases: (a) a preparator

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Background: Serum protein profiles have been investigated frequently to discover early biomarkers for breast cancer. So far, these studies used biological samples collected at or after diagnosis. This may limit these studies' value in the search for cancer biomarkers because of the often advanced tumor stage, and consequently risk of reverse causality. We present for the first time pre-diagnostic

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Background: Women working in the public human service sector in 'overstrained' situations run the risk of musculoskeletal symptoms and long-term sick leave. In order to maintain the level of health and work ability and strengthen the potential resources for health, it is important that employees gain greater control over decisions and actions affecting their health - a process associated with the

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Understanding factors that limit gene flow through the landscape is crucial for conservation of organisms living in fragmented habitats. We analysed patterns of gene flow in Elater ferrugineus, an endangered click beetle living in old-growth, hollow trees in a network of rural avenues surrounded by inhospitable arable land. Using amplified fragment length polymorphism (AFLP) data, we aimed to eval

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Background: Tumor associated macrophages (TAMs) are alternatively activated macrophages that enhance tumor progression by promoting tumor cell invasion, migration and angiogenesis. TAMs have an anti-inflammatory function resembling M2 macrophages. CD163 is regarded as a highly specific monocyte/macrophage marker for M2 macrophages. In this study we evaluated the specificity of using the M2 macroph

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Allergic contact dermatitis (ACD) develops upon exposure to certain chemical compounds termed skin sensitizers. To reduce the occurrence of skin sensitizers, chemicals are regularly screened for their capacity to induce sensitization. The recently developed Genomic Allergen Rapid Detection (GARD) assay is an in vitro alternative to animal testing for identification of skin sensitizers, classifying

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Abstract For activity quantification based on planar scintillation camera measurements, photon attenuation is an important factor that needs to be corrected for in a patient- and organ-specific manner. One possibility for obtaining attenuation correction maps is to use X-ray CT scout images. Since the intensity of scout images is in relative numbers, their image values need to be multiplied by a f

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Background- This nationwide study sought to determine age- and gender-specific familial risks in siblings hospitalized for venous thromboembolism (VTE). Methods and Results- The Swedish Multigeneration Register on 0- to 75-year-old subjects was linked to the Hospital Discharge Register for the years 1987-2007. Standardized incidence ratios were calculated for individuals whose siblings were hospit

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The sub-cell-fix (SCF) method proposed by Russo and Smereka(3) computes the distance function of the cells adjacent to the zero level-set without disturbing the original zero level-set. A modified sub-cell-fix scheme independent of local curvature is developed in this paper, which makes use of a combination of the points adjacent to zero level-set surfaces and preserves the interface in a second-o

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This thesis set out to map the relation Swedish farmers have to their occupation and production, while also investigating what challenges farmers experience which in turn might affect social sustainability in Swedish agriculture negatively. Agriculture was approached as a case of low social sustainability based on the fact that more than one-third of Swedish farmers are over retiring age, while yo

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Public Opinion about Sweden during the COVID-19 Pandemic and Implications for its Nation Brand: A Sentiment Analysis This thesis seeks to expand the understanding of nation brand image perceptions by exploring the opinions of international audiences about Sweden during the COVID-19 pandemic in the form of sentiments. Given the strong link between a country’s handling of the COVID-19 pandemic and