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In Sweden, municipalities organize a large share of public services but the conditions for providing these services differ considerably due to differences in size and wealth. In the wake of financial stress and New Public Management reforms the Swedish local governments seeks new ways to make both ends meet and still manage the services to be in line with the present (not the past) demands of the

This thesis is divided into two parts in which two different aspects of the Large Hadron Collider (LHC) Project are discussed. The first part describes the design of a transition radiation tracker (TRT) for the inner detector in ATLAS. In particular, the barrel part was studied in detail. The barrel TRT consists of 52 544 1.5-m-long proportional tubes (straws), parallel to the beam axis and each

Proton exchange membrane fuel cell (PEMFC) systems have been investigated as alternative power sources for the stationary and automotive applications. However, they do not appear on the market yet. One of the main reasons is the difficulty of the water/thermal management in the system. Several water recovery schemes have been proposed to overcome this difficulty and to simplify the system configur

The Single Molecule Spectroscopy Group at the department of Chemical Physics in the Chemical Centre of Lund University conducts research involving spectroscopy on single molecules of organic dyes. Fluorescence microscopy using a wide-field scheme has been used and such a scheme has many advantages such as full image capture at once when using a high sensitivity CCD or CMOS camera. Using different

Sociala hänsynstaganden, som exempelvis spelberoende, minderårigas spelande samt förebyggandet av brottslighet och bedrägeri, har traditionellt motiverat Medlemsstaternas nästintill ovillkorliga rätt att reglera spel på nationell nivå. När spel på Internet introducerades valde EU-domstolen att applicera samma argument och fortsätta bekräfta denna rätt. Internetspel har dock förändrat den traditionConcerns of public interest, such as the prevention of problem gambling, underage gambling and evading the risks of crime and fraud, have in the jurisprudence of the CJEU traditionally been used to justify a wide discretionary right for the Member States to regulate gambling. When online gambling was introduced, the CJEU decided to apply the same arguments and continue to affirm the strong rights

Utvärdering av ett målprotein för behandling av ledgångsreumatism Reumatisk artrit (RA), eller ledgångsreumatism som det också kallas, är en autoimmun sjukdom som 1% av världens befolkning lider av. Kroppens egna immunceller blir autoreaktiva och attackerar lederna i främst händer och fötter. Den ökade mängden immunceller i de här lederna resulterar i svullnad och inflammation, men även ben och bRheumatoid arthritis is an autoimmune disease resulting in swelling and destruction of bone and cartilage within the small joints. The mechanism behind the disease is not fully understood, but the interaction of autoreactive T-cells with effector cells like B-cells and macrophages through cytokine signaling is believed to be important. A potential target for drug development against arthritis that

Increasing awareness and change in attitudes towards environment has given rise to the sustainable development and this development has stimulated environmental innovations globally in the last years. The recent studies show that in near future there will be more packaging solutions from renewable resources. The purpose of this thesis is to investigate how a brand owner using renewable packaging m

This master thesis work consists of the development of new hardware and software for the control box of an azimuthal guidance system used by aircrafts during the approach to the runway. The thesis work was done at Safegate International AB as a project running along the usual development projects. When designing electronics to be used on an airfield there are a lot of regulations and standards t

Dementia is one of the burdensome diseases in older age for which there is no cure known. The demand for carers of dementia patients is growing as the population ages. We analyse serious games as an approach to provide dementia carers with training on care related problem solving and modelling real-world cases. We present the behaviour model of improved care process by applying serious games, desc

A search for the narrow structure, X(5568), reported by the D0 Collaboration in the decay sequence X→Bs0π±, Bs0→J/ψφ, is presented. The analysis is based on a data sample recorded with the ATLAS detector at the LHC corresponding to 4.9 fb-1 of pp collisions at 7 TeV and 19.5 fb-1 at 8 TeV. No significant signal was found. Upper limits on the number of signal events, with properties corresponding t

A socially mixed population is a political ambition in Stockholm. By providing a mix of tenure alternatives throughout all neighbourhoods this objective could, at least partially, be fulfilled. Since current tenure proportions display a weak balance in many neighbourhoods it could be assumed that governing politicians – by primarily utilizing Stockholm’s vast landownership and municipal housing de

The breast cancer risk variants identified in genome-wide association studies explain only a small fraction of the familial relative risk, and the genes responsible for these associations remain largely unknown. To identify novel risk loci and likely causal genes, we performed a transcriptome-wide association study evaluating associations of genetically predicted gene expression with breast cancer

There is an unmet clinical need for objective biomarkers to monitor disease progression and treatment response in Huntington's disease (HD). The aim of this review is, therefore, to provide practical advice for biomarker discovery and to summarise studies on biofluid markers for HD. A PubMed search was performed to review literature with regard to candidate saliva, urine, blood and cerebrospinal f