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Comparing three methods for lipid identification using mass spectrometry - Data-independent, data-dependent and targeted acquisition
Introduction: This study evaluated lipid identification using mass spectrometry. Background: Three main modes of acquisition are used in mass spectrometry of lipids; data-independent acquisition (DIA), data-dependent acquisition (DDA) and targeted acquisition. DIA is the most including one, yielding a complete but complex data set, while targeted is the least including one, basing acquisition on
Verksam i "annat fåmansföretag", vilket? - En skatterättslig studie av 57 kap. 4 § 1 st. 2 p. IL och därtill hörande frågor
3:12-reglerna har idag funnits i 25 års tid och har reviderats ett stort antal gånger i syfte att ändra, täppa till, komplettera och lappa ihop desamma. Detta har fått till följd att regelsystemet idag är mer komplext än någonsin, till stor nackdel för den stora andel fåmansföretagare som idag bedriver verksamhet i Sverige. En av de bestämmelser som omfattas av 3:12-reglerna är 57 kap. 4 § 1 st.The so called 3:12 rules have today now been in use for almost 25 years and have since the beginning been amended many times in order to change, cover up, complete and patch up themselves. This has resulted in a very complex regulation, which has made it difficult for close companies, which make up the majority of all corporations in Sweden, to do business. As part of the 3:12 rules is the regula
Design and Development of a Virtual Reality Application to Introduce Gesture-Based Interaction
This thesis provides insight into the development of Virtual Reality(VR) applications with the purpose of introducing users to a new gesture interaction platform. Gesturebased interaction and VR are two rapidly evolving technologies with a great potential to complement each other. The gestures used are based on a cognitive model of holding a sphere in your hands and tapping on its surface. By usin
Lp-PLA2 activity and mass for prediction of incident abdominal aortic aneurysms : A prospective longitudinal cohort study
Background and aims The pathogenesis of abdominal aortic aneurysm (AAA) shares several common pathways with atherosclerosis. Prospective clinical plasma biomarker studies in AAA have been hampered by the need for very large cohorts and long follow-up time. Methods We analyzed a prospective longitudinal cohort of middle-aged individuals from the cardiovascular cohort of the Malmö Diet and Cancer st
ASSOCIATION OF BTG2, CYR61, ZFP36, AND SCD GENE POLYMORPHISMS WITH GRAVES' DISEASE AND OPHTHALMOPATHY.
Background: Environmental and genetic factors predispose an individual to the development of Graves' disease (GD). In an expression study of intraorbital tissue, adipocyte-related immediate early genes (IEGs) and immunomodulatory genes were found to be overexpressed in patients with Graves' ophthalmopathy (GO). We hypothesized that genetic variations in these genes could be associated with GD and/
Imaging of gynecological disease (3): clinical and ultrasound characteristics of granulosa cell tumors of the ovary
Objectives To describe the clinical and ultrasound characteristics of granulosa cell tumors (GCTs) of the ovary, and to define the ultrasound appearance of GCTs based on pattern recognition. Methods Databases of four gynecological ultrasound centers were searched to identify patients with histologically proven GCTs who had undergone a standard preoperative ultrasound examination. Results A total o
Manual correction of semi-automatic three-dimensional echocardiography is needed for right ventricular assessment in adults; validation with cardiac magnetic resonance
Background: Three-dimensional echocardiography (3DE) and semi-automatic right ventricular delineation has been proposed as an appropriate method for right ventricle (RV) evaluation. We aimed to examine how manual correction of semi-automatic delineation influences the accuracy of 3DE for RV volumes and function in a clinical adult setting using cardiac magnetic resonance (CMR) as the reference met
Comorbidities and Mortality in Persons With Schizophrenia: A Swedish National Cohort Study
Objective: Schizophrenia is associated with premature mortality, but the specific causes and pathways are unclear. The authors used outpatient and inpatient data for a national population to examine the association between schizophrenia and mortality and comorbidities. Method: This was a national cohort study of 6,097,834 Swedish adults, including 8,277 with schizophrenia, followed for 7 years (20
NORMER OCH NORMALITET - En normvetenskaplig textanalys av argumentation runt homosexuellas adoptionsrätt
SV: I januari 2003 fick homosexuella registrerade partners rätt att prövas som adoptivföräldrar i Sverige, i enlighet med en proposition från 2001. Beslutet kom först efter en lång debatt; redan 1986 lades en proposition fram som behandlade frågan och avslog den. Denna uppsats är en studie av de argument som förkommer i propositionerna. Syftet har varit dels att beskriva och analysera de argument
Utformning av stationer i mindre samhällen
Summary The station has always played an important role in development. In Sweden, railway building started in the middle of the 1900th century. The government financed the main rail lines, while private railway companies financed the small lines. The expansion of the railway lines was lead and planned by militaries, therefore the stations generally were drawn by trained militaries. Several statio
Prototypframtagning av Milkbar
The background to this master thesis is that various studies show that the milk consumption in Swedish schools is decreasing. Offering flavored milk will hopefully make milk more attractive. The concept with flavored milk has previously been tested in a prestudy where a rig were made to test the basic idea. There is now an interest in taking the project to the next level by building a prototype. T
A New Bridge Proposal - Road Bridge with a Cross-Laminated Timber Slab
Should it move or should it stay? How speakers of two Basque dialects organize meaningful elements in transitive clauses
Interactive Effects of Aerobic Fitness, Strength, and Obesity on Mortality in Men
Introduction: Low aerobic fitness, low muscular strength, and obesity have been associated with premature mortality, but their interactive effects are unknown. This study examined interactions among these common, modifiable factors, to help inform more-effective preventive interventions. Methods: This national cohort study included all 1,547,478 military conscripts in Sweden during 1969-1997 (97%-
ECG-derived spatial QRS-T angle is strongly associated with hypertrophic cardiomyopathy
Introduction: ECG-derived vectorcardiography (VCG) has diagnostic and prognostic value in various diseases. Hypertrophic cardiomyopathy (HCM), a genetic disease with unexplained left ventricular hypertrophy, is one of the most common causes of sudden cardiac death (SCD) in young persons. Genotype positive status is associated with increased risk of systolic dysfunction, heart failure, and (SCD). H
Type 2 diabetes, adiposity and cancer morbidity and mortality risk taking into account competing risk of noncancer deaths in a prospective cohort setting
Waist/Hip Ratio Better Predicts Development of Severe Liver Disease Within 20 Years Than Body Mass Index : A Population-based Cohort Study
Background & Aims Obesity, commonly assessed based on body mass index (BMI), is associated with an increased risk for severe liver disease. It is not known if other measures of body composition are better determinants of risk for severe liver disease, and/or if these differ between women and men. We investigated the body composition measures that best predict the development of severe liver di
Prevalence and treatment of diabetes mellitus and hypertension among older adults with intellectual disability in comparison with the general population
BACKGROUND: Diabetes mellitus and hypertension are risk factors for cardiovascular disease, which is the most common cause of death in the world. People with intellectual disability (ID) have been reported to have high rates of both these disorders. The aim of this study was to describe and compare prevalence ratios of diabetes mellitus and hypertension between older adults with ID and their age p
Video capsule colonoscopy in routine clinical practice
Background: Colon capsule endoscopy (CCE) offers direct mucosal visualisation without sedation or gas insufflation required in conventional colonoscopy (CC). However, evidence for the role of CCE as an adjunct or alternative to CC remains equivocal. In this observational cohort study, we report our experience of using CCE to investigate patients with suspected colon pathology at a tertiary referra
