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Effect of Pramipexole on Nucleus Accumbens Resting State Functional Connectivity in Anhedonia – an fMRI Study

Anhedoni, minskad motivation att uppleva lust, är associerad med förändringar i belöningssystemet. Belägen i ventrala striatum utgör den bilaterala nucleus accumbens (NAcc) den centrala noden i detta nätverk, där dopamin agerar som huvudsaklig excitatorisk neurotransmitter. Studier med funktionell magnetresonanstomografi (fMRI) har visat att aktiviteten i ventrala striatum minskar under belöningsbAnhedonia, reduced motivation to experience pleasure, is associated with alterations in the circuitry of the reward system. Located in the ventral striatum, the bilateral nucleus accumbens (NAcc) is the central hub of this network where dopamine acts as the main excitatory neurotransmitter. Studies using functional magnetic resonance imaging (fMRI) found that activity in the ventral striatum is de

Two Sides of the Same Coin? A Preliminary Analysis of Sustainable Development Opportunities Identified in National Communications of Non-Annex I Parties

The aim of this paper is to study the extent to which non-Annex I countries are implementing or exploring select actions that support both climate change mitigation and sustainable development objectives in the energy sector. The research is based on a survey of the national communications of 100 non-Annex I Parties to the UNFCCC. Although national communications are intended to provide informatio

Two Sides of the Same Coin? A Preliminary Analysis of Sustainable Development Opportunities Identified in National Communications of Non-Annex I Parties

The aim of this paper is to study the extent to which non-Annex I countries are implementing or exploring select actions that support both climate change mitigation and sustainable development objectives in the energy sector. The research is based on a survey of the national communications of 100 non-Annex I Parties to the UNFCCC. Although national communications are intended to provide informatio

The other side of the coin: the e-government implementation in an Italian municipality

This paper ad to the body of knowledge on the implementation ofthe e-Government and aims to describe how this process was carried out inthe Delta municipality in Northern Italy. This organization is a public organization in an economically important Region and provides services to entrepreneurs such as validation for opening a new business. An interpretativeapproach used with several interviewees

Cancer and autoimmunity: two sides of the same coin. Complement system proteins in the regulation of immune responses.

Factor H is an inhibitor of the complement system, essential for controlling the alternative pathway and also playing a crucial role in various cellular functions. In this thesis, we identified new intriguing functions of FH as a survival factor for primary human monocytes, promoting their differentiation into immunosuppressive macrophages. We showed that FH is expressed by human breast cancer cel

Coins have both sides : Revealing the structure and pattern of global interdependence network for five critical metals

Evaluating the trade interdependence among countries is the key to understanding critical metal minerals security. By constructing a novel interdependence network, this paper reveals a more comprehensive world hierarchy and risk system of critical metals, and focuses on the interdependencies between China and the US-led MSP countries before and after the Sino-US trade disputes. The results indicat

Two Sides to the Same Coin: The Dual Life of Consultants in Employee and Employer Branding

Purpose: This research aims to gain an understanding on how consultants in small consultancies, who also hold internal human resource responsibilities, promote their organisation in employee and employer branding. Relevance: Due to the ambiguous consultancy profession and the high potential for individual influences on the corporate brand, branding becomes a very germane topic in our particular r

Explaining environmental behavior with values, worldviews, and self-construal: Different sides of the same coin?

Values, worldviews, and self-construal are strong correlates of pro-environmental behavior. In this brief empirical note, we argue that these constructs overlap conceptually and share underlying dimensions. Using an international sample of 11,964 individuals, we demonstrate that values, worldviews, and self-construal can be reduced to two dimensions, self-focus and other-focus, capturing 67 % of v

Two Sides of the Same Coin: Bootstrapping the Restricted vs. Unrestricted Model

The properties of the bootstrap test for restrictions are studied in two versions: 1) bootstrapping under the null hypothesis, restricted, and 2) bootstrapping under the alternative hypothesis, unrestricted. This article demonstrates the equivalence of these two methods, and illustrates the small sample properties of the Wald test for testing Granger-Causality in a stable stationary VAR system by

The two sides of the coin : joint project leader interaction in university-industry collaboration projects

This article focuses on how academic and industrial leaders view central aspects of the initiation, collaboration process, and the outcomes in government-funded R&D projects. In much previous work on university-industry collaborations (UICs), universities or researchers and/or firms have been studied without any direct reference to the other party, thus neglecting the fact that the motivations