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Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase, E.C. 3.6.1.23) catalyzes the hydrolysis of dUTP to dUMP and pyrophosphate and is involved in nucleotide metabolism and DNA synthesis. A crystal of the recombinant E. coli enzyme, precipitated from polyethylene glycol mixtures in the presence of succinate at pH 4.2, was used to collect synchrotron diffraction data to 1.9 Å resolution, in sp

Astrand H, Stalhand J, Karlsson J, Karlsson M, Sonesson B, Lanne T. In vivo estimation of the contribution of elastin and collagen to the mechanical properties in the human abdominal aorta: effect of age and sex. J Appl Physiol 110: 176-187, 2011. First published November 11, 2010; doi:10.1152/japplphysiol.00579.2010.-The mechanical properties of the aorta affect cardiac function and are related t

Abstract in UndeterminedMany species of birds show evidence of secondary contact zones and subspeciation in their Scandinavian distribution range, presumably resulting from different post-glacial recolonization routes. We investigated whether this is the case also in the Scandinavian bluethroat Luscinia svecica, a species that has been suggested to consist of two separate populations: one SW-migra

This thesis concerns paragraph 30, 31 and 32 of the Consumer Insurance Act. The Consumer Insurane Act was adopted in 1981. It is applicable to combined insurance policies covering fire, burglery, liability, and certain other risks when the insured party is a consumer. In these cases, the Consumer Insurance Act is applicable to motor vehicle-, yachting- and travelling insurance contracts as well.

Denna bok handlar om de franska S:t josefsystrarna och deras missionsverksamhet i Skandinavien från mitten av 1800-talet och fram till 1950-talet med fokus på deras skol- och sjukvårdsverksamhet samt den specifika kvinnokultur som de representerade.Female Counter-Culture and Catholic Mission. The St Joseph Sisters in Denmark and Sweden 1856-1936 In May 1856, four Catholic sisters arrived in Denmark and established a community in a small basement of a building close to the Catholic parish church in Copenhagen. These Catholic sisters belonged to a French religious congregation named "La Congregation des Sœurs de Saint-Joseph de Chambéry", whi

Romania has for a long time been lacking good palaeoenvironmental records, particularly for the Late Quaternary. A chronological framework had been nearly absent and the vegetation development had been reconstructed entirely from pollen data. Data sets from this part of Europe are important for assessing the spatial variability of past vegetation and climatic changes and to reconstruct tree migrat

The integrating properties of the atmospheric boundary layer allow the influence of surface exchange processes on the atmosphere to be quantified and estimates of large-scale fluxes of trace gases and plant isotopic discrimination to be made. Five flights were undertaken over two days in and above the convective boundary layer (CBL) in a vegetated region in central Siberia. Vertical profiles of CO

The goal of this research is to use hematopoietic cells as vehicles for targeting transgenic immunomodulators to the inflammatory sites. The work presented was focused on the anti-inflammatory soluble TNF receptor. A transmembrane soluble TNF receptor (sTNFR1) construct was expressed in hematopoietic cell lines. ER export was facilitated by addition of a transmembrane (tm) sequence, and constituti

Objective: Postprandial hyperlipemia, characterized by increased circulating very low-density lipoproteins (VLDL) and circulating lipopolysaccharide (LPS), has been proposed as a mechanism of vascular injury. Our goal was to examine the interactions between postprandial lipoproteins, LPS, and apoE3 and apoE4 on monocyte activation. Methods and Results: We showed that apoE3 complexed to phospholipi

BACKGROUND: Our recently reported finding of rapid bi-exponential elimination of free prostate-specific antigen (PSA) after radical retropubic prostatectomy in patients with moderately elevated PSA levels, which contrasted a very slow, linear elimination of PSA complexed to alpha-1-antichymotrypsin (ACT), prompted us to study whether these elimination rates were applicable for patients selected fo

Introduction: Activation recovery time (ART), defined as the time from the earliest ventricular activation time to the end of T wave on unipolar electrograms, has been used as an index of myocardial repolarization time. However, it is unknown whether the ART can be used to estimate the global sequence and dispersion of ventricular repolarization as determined by the monophasic action potential (MA

Context/Objective: To effectively normalize IGF-I in patients with acromegaly, various covariates may affect dosing and plasma concentrations of pegvisomant. We assessed whether sex, age, weight, and previous radiotherapy influence dosing of pegvisomant in patients with active disease. Design: Data from 69 men and 49 women participating in multicenter, open-label trials of pegvisomant were retrosp

Accurate methods to preoperatively characterize adnexal tumors are pivotal for optimal patient management. A recent meta-analysis concluded that the International Ovarian Tumor Analysis (IOTA) algorithms such as the Simple Rules are the best approaches to preoperatively classify adnexal masses as benign or malignant. We sought to develop and validate a model to predict the risk of malignancy in ad

Late Quaternary tree-ring chronologies have been constructed using data collected from subfossil trees preserved under favourable conditions in lake sediments and peat deposits. Tree-ring widths and densities are commonly used for reconstructions of past climate variability. An alternative way of using these data is to explore the replication curves of these chronologies. Here, we make use of prev

In forest biomass estimations, three dimensional (3D) canopy structure data derived from images captured by unmanned aerial vehicles (UAVs), also known as drones, has shown potential due to the flexibility and cost efficiency of the method. However, little research has been done for its applicability in bioenergy forest. In this study, a method was developed with the purpose of remotely estimating

Göta älv är Sveriges största vattendrag som sträcker sig från Vänern ner till Kungälv där bifurkationen delar den i Nordre älv och Göta älv (Göteborgsgrenen). Vattendraget är ett riksintresse och används bland annat för fiske, rekreation, som recipient och framförallt råvattentäkt för många kringliggande vattenverk som försörjer cirka 700 000 invånare. Kungälv kommun bygger och planerar inför ettGöta älv is the largest river in Sweden, which runs from the Lake Vänern into Kattegatt. The river is of national interest and is used as a drinking water supply for 700 000 inhabitants, for fishing, recreation and as a recipient for treated wastewater. The water quality is affected by runoff waters, precipitation, waste water and accidental spills from industry and vessels. Kungälv County is in

Recent urban development has serious consequences such as limited space and expanded urban sprawl which lead to complex problems on the edge. Also, there is large number of urbanization where people from rural areas try to find better opportunities by moving to big cities. Furthermore, fringe area seems like an unplanned area which lose its identity and do not optimize its potentials. Those situat

This is a comparative study of several widespread and canonical texts from the lowlands of the Middle East and North Africa, with regard to historically reoccurring interconnected traits of ideal state structure among cultures, where Semitic languages have been main languages of communication from the 18th century BC to the modern day. The study is of reoccurring ideals of state structure with def