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The effect of mild proteolytic treatment on chylomicron remnant uptake by rat hepatocyte monolayers was studied both at 4 degrees C and at 37 degrees C. At 4 degrees C binding of remnants to the cells was considerably lower than at 37 degrees C, and preincubation of the cells with pronase (2 micrograms/ml) further descreased binding of remnants at 4 degrees C by 63%. At 37 degrees C the effect of
Serotonin (5-hydroxytryptamine) has repeatedly been associated with the development of fibrotic disorders such as pulmonary fibrosis. By blocking the binding of 5-HT to 5-HT2B receptors with receptor antagonists, several pro-fibrotic mechanisms can be inhibited. Bleomycin-induced pulmonary fibrosis is a model used to evaluate pathological mechanisms and pharmacological interventions. Previously we
Gender assignment in languages with a gender system is a complex issue, as this can be influenced by both semantic, morphological, and phonological factors (Corbett, 1991, 2013; Corbett & Fraser, 2000). Many Indo-European languages possess a three-gender system, which distinguishes masculine, feminine, and neuter gender. Whereas this system is preserved in several Indo-European branches, it ha
The use of Alcohol-based antiseptics is efficient and approved, however it has some limitations. This paper examined the possibility of using hypochlorite water as a chlorine-based antiseptic for handwashing in public buildings and healthcare facilities. The electrolysis method was used, which produces Hypochlorous acid (HOCl) from mixing drinking water with small amounts of sodium hydroxide. Hypo
Kostnaden för vårdsamordnare för sköra äldre utvärderad – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kostnaden för vårdsamordnare för sköra äldre utvärderad 2015-08-31 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Skåne var tidigt ut
https://www.vetenskaphalsa.se/kostnaden-for-vardsamordnare-for-skora-aldre-utvarderad/ - 2026-06-19
Organic micropollutants comprise a diverse set of molecules, varying both with regard to the frequency of their use, as well as the potential harm they can inflict upon aquatic ecosystems. Ozonation has been recognized as an efficient method for their abatement, due to its ability to selectively oxidize molecular groups commonly found on organic molecules. Micropollutants are, however, rarely degr
Förskolorna måste göra mer på hälsoskyddsområdet än att lära barn tvätta händerna Samtliga förskolor i Lomma Kommun har under 2012 och 2013 inspekterats av miljökontoret för att följa upp Socialstyrelsens projekt om hygien och smittskydd i förskolan från 2009. Resultatet visar att de 24 förskolorna i Lomma Kommun har bra rutiner för hygien, smittskydd och städning. Andra områden som krävs enligStudies have showed that children that are spending their daytime at preschools suffer from more infections than children who stay at home. The indoor environment has a big impact on our health and therefore it must be good and suitable for the children in preschools. According to the Swedish environmental laws preschools must set- up preventive work to avoid environmental and health problems an
The main purpose of this study is to investigate how Swedish university students in Lund within the ages of 20 to 30 years old are affected by alcohol commercials and what effect the commercials have on shifts in attitude.The study is based on a deductive process with a quantitative research strategy, which resulted in the formation of the study’s hypotheses. A survey was conducted to test these h
The debate on the industrial revolution (IR) has been focused on the incentives behind investment decisions and how the preliminary conditions for it appeared in England / Great Britain. One of the most famous theories to explain the IR is the one developed by Allen (2012, 2009b,a), who argues that the IR was British due to a unique combination of expensive labour and cheap energy, producing incen
Assessing vector-parasite relationship is important in understanding the emergence of vector-borne diseases and the evolution of parasite diversity. This study investigates avian Plasmodium parasites in mosquitoes collected from Kayseri province in Central Anatolian, Turkey and determines the haemosporidian parasite lineages from these mosquito species. A total of 6153 female mosquitos from 6 spec
Objective: Regulation of immune-like cell properties of periodontal ligament (PDL) cells is not understood. We investigate the importance of secretory leukocyte protease inhibitor (SLPI) for production of pro-inflammatory cytokines in human PDL cells. Materials and methods: PDL cells were isolated from teeth extracted for orthodontic reasons. Cellular location of SLPI was investigated by immunocyt
Amine transaminase (ATA) catalyse enantioselectively the direct amination of ketones, but insufficient stability during catalysis limits their industrial applicability. Recently, we revealed that ATAs suffer from substrate-induced inactivation mechanism involving dissociation of the enzyme-cofactor intermediate. Here, we report on engineering the cofactor-ring-binding element, which also shapes th
Efficient handling of faults during operation is highly dependent on the interval (latency) from the time embedded monitoring instruments detect faults to the time when the fault manager localizes the faults. In this article, we propose a self-reconfiguring IEEE 1687 network in which all instruments that have detected faults are automatically included in the scan path, and a fault detection and lo
Lytic polysaccharide monooxygenases (LPMOs) are copper metalloenzymes that can enhance polysaccharide depolymerization through an oxidative mechanism, making them interesting for the production of biofuel from cellulose. However, the details of this activation are unknown; in particular, the nature of the intermediate that attacks the glycoside C–H bond in the polysaccharide is not known, and a nu
In this work, extraction and characterization of compounds with antioxidant and antimicrobial activity from Haematococcus pluvialis microalga in red phase have been carried out. To do this, subcritical water extraction (SWE) has been combined with analytical techniques such as HPLC-DAD, HPLC-QqQ-MS and GC-MS and in vitro assays (i.e., for antioxidant and antimicrobial activity). The effect of the
Methane is a powerful greenhouse gas and growing concern regarding global climate changes over the last years has pointed out the need to quantify and control the leaking of methane into the atmosphere. Landfill gas is regarded as one of the major sources for methane migration to the atmosphere. In this study we present research work with the objective to evaluate the use of geoelectrical resistiv
BMP receptors determine the intensity of BMP signals via Smad1 C-terminal phosphorylations. Here we show that a finely controlled cell biological pathway terminates this activity. The duration of the activated pSmad1Cter signal was regulated by sequential Smad1 linker region phosphorylations at conserved MAPK and GSK3 sites required for its polyubiquitinylation and transport to the centrosome. Pro
The most common pediatric malignancy is acute lymphoblastic leukemia (ALL), of which T-cell ALL (T-ALL) comprises 10–15% of cases. T-ALL arises in the thymus from an immature thymocyte as a consequence of a stepwise accumulation of genetic and epigenetic aberrations. Crucial biological processes, such as differentiation, self-renewal capacity, proliferation, and apoptosis, are targeted and derange
