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Innovating for an ageing society : insights from two Japanese smart cities

Smart cities are enthusiastically promoted around the world by industry and governments alike as a desirable means to achieve urban sustainability. This chapter contributes empirical evidence on how projects reflecting qualities of a Smart City 2.0 model can play out on the ground. It examines two Japanese smart cities addressing the interconnected challenges of an ageing society and preventative

Shedding new light on opsin evolution

Opsin proteins are essential molecules in mediating the ability of animals to detect and use light for diverse biological functions. Therefore, understanding the evolutionary history of opsins is key to understanding the evolution of light detection and photoreception in animals. As genomic data have appeared and rapidly expanded in quantity, it has become possible to analyse opsins that functiona

A genomic and historical synthesis of plague in 18th century Eurasia

Plague continued to afflict Europe for more than five centuries after the Black Death. Yet, by the 17th century, the dynamics of plague had changed, leading to its slow decline in Western Europe over the subsequent 200 y, a period for which only one genome was previously available. Using a multidisciplinary approach, combining genomic and historical data, we assembled Y. pestis genomes from nine i

Methane dynamics in northern wetlands: Significance of vascular plants

Popular Abstract in Swedish Metan är en växthusgas med stor potential att påverka klimatet på Jorden. Den vattenmättade miljön i våtmarker erbjuder perfekta livsbetingelser för metanproducerande bakterier och detta medför att naturliga våtmarker är den största enskilda källan till metan i atmosfären, även då man räknar med antropogena utsläpp från, till exempel, förbränning av fossila bränslen. MoThe studies presented in Papers I to VI illustrate several different aspects of the impact of vascular plants on methane emissions from northern natural wetlands. The subject has been approached on different scales, ranging from the study of microbial substrates in the vicinity of a single plant root, to an attempt to extrapolate some of the results to the entire northern hemisphere north of 50°N.

The CDK-activating kinase (Cak1p) from budding yeast has an unusual ATP binding pocket

Cak1p is an essential protein kinase that phosphorylates and thereby activates the major cyclin-dependent kinase in budding yeast, Cdc28p. The sequence of Cak1p differs from other members of the protein kinase superfamily in several conserved regions. Cak1p lacks the highly conserved glycine loop motif (GXGXXG) that is found in the nucleotide binding fold of virtually all protein kinases and also

Simulated time-lapse dc-IP monitoring of dense non-aqueous phase liquids (DNAPLs)-An Initial Approach

Geoelectrical techniques have long standing potential for imaging sites contaminated by dense non-aqueous phase liquids (DNAPLs). Recent work explored the effectiveness of time-lapse DC resistivity to monitor DNAPL source zone remediation. A fundamental component of the work was the development of a unique and comprehensive linkage between well-established DNAPL and DC resistivity models, with the

Superlattice formation in the lithiated vanadium oxide phases Li0.67V6O13 and LiV6O13

Two new lithiated phases of V6O13 were formed by carefully tuning the temperature of electrochemical lithiation in a 'coffee-bag' type Li-ion battery at 2.78 V versus Li/Li+. These were studied by single-crystal X-ray diffraction. A phase with the composition Li2/3V6O13 was obtained at 308 K with a unit cell three times the volume of the original V6O13 cell. A single crystal discharged at ambient

Modeling of a solar dryer for fruit preservation in developing countries

About 25,3 % of the Mozambican population is suffering from undernourishment even though a sufficient amount of food and specifically fruits are produced. Post-harvest losses are estimated to 25 % to 40 % and part of the production is not even harvested due to a short season. A solution has to be found to improve fruit preservation and allow the population to consume what is harvested later. Dryin

Novel tenascin variants with a distinctive pattern of expression in the avian embryo

Previous studies have shown that several forms of the glycoprotein tenascin are present in the embryonic extracellular matrix. These forms are the result of alternative splicing, which generates tenascin variants with different numbers of fibronectin type III repeats. We have used degenerate primers and PCR to isolate a novel tenascin exon from an avian genomic library. Genomic clones contained a

Air inlet angle influence on the air-side heat transfer and flow friction characteristics of a finned oval tube heat exchanger

In this study, the influence of various air inlet angles on the heat transfer and flow friction characteristics of a 2-row plain finned oval tube heat exchanger is analyzed by experimental and numerical methods. The experimental results show that an air inlet angle 45° provides the best heat transfer performance, and an air inlet angle 90° provides the smallest pressure drop, while an air inlet an

An mTRAN-mRNA interaction mediates mitochondrial translation initiation in plants

Plant mitochondria represent the largest group of respiring organelles on the planet. Plant mitochondrial messenger RNAs (mRNAs) lack Shine-Dalgarno-like ribosome-binding sites, so it is unknown how plant mitoribosomes recognize mRNA. We show that “mitochondrial translation factors” mTRAN1 and mTRAN2 are land plant–specific proteins, required for normal mitochondrial respiration chain biogenesis.

Intraneuronal Alzheimer Aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology

A central question in Alzheimer's disease concerns the mechanism by which β-amyloid contributes to neuropathology, and in particular whether intracellular versus extracellular β-amyloid plays a critical role. Alzheimer transgenic mouse studies demonstrate brain dysfunction, as β-amyloid levels rise, months before the appearance of β-amyloid plaques. We have now used immunoelectron microscopy to de

RE:WATERFRONT : A sustainable architectural approach

RE:WATERFRONT evaluates theories and results from an interdisciplinary design experience with focus on urban architecture in sustainability discourse. Taking the design teaching of “RE:WATERFRONT: Post-industrial harbor transformation at Frihamnen in Gothenburg, Sweden” as a case study, this book intends to tackle the theme of re-development in urban voids. The aim is to introduce a methodological

Finding Gender at the Intersection of Family and Field : Family Presences in Sweden

Gender influences how researchers engage with the field (Porter & Schänzel, 2018). Departing from this proposition, this chapter offers reflections on gender from masculine vantages in the context of a qualitative research project investigating tourism enterprising in southern Sweden. Tourism enterprising is an important aspect of tourism development. Focusing on personal experiences associate

With increasing age at tumor diagnosis in familial cancer: Cancer is limited to fewer organs

Hereditary cancer that has monogenic inheritance affects every tenth patient, on average, who is diagnosed with cancer, and it has been suggested, based on twin studies, that approximately 30% of all cancer patients have a genetic predisposition to developing cancer. In this article, the author posited that familial syndromes become more organ specific with increasing age at tumor presentation to

Juxtaposed narrative : The dilemma of cultural memory on display in George Town’s street art

Street art is a ubiquitous visual landmark in contemporary George Town, the capital city of Penang state in Malaysia. Both private commissioned and state-sanctioned types of street art are the new significant cultural identification of this World Heritage Site city as inscribed by UNESCO in 2008. Street art in this multicultural city becomes the articulated media that deals with the notion of cult

Catch Me if You Can : Streptococcus pyogenes Complement Evasion Strategies

The human host has evolved elaborate protection mechanisms to prevent infection from the billions of microorganisms to which it host is exposed and is home. One of these systems, complement, is an evolutionary ancient arm of innate immunity essential for combatting bacterial infection. Complement permits the efficient labelling of bacteria with opsonins, supports phagocytosis, and facilitates phag

Wild African Drosophila melanogaster are seasonal specialists on marula fruits

Although the vinegar fly Drosophila melanogaster isarguably the most studied organism on the planet,fundamental aspects of this species’ natural ecologyhave remained enigmatic [1]. We have here investigateda wild population of D. melanogaster from amopane forest in Zimbabwe. We find that these fliesare closely associated with marula fruit (Sclerocaryabirrea) and propose that this seasonally abunda