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Procedural sedation and analgesia outside the operating theater have become standard care in managing pain and anxiety in children undergoing diagnostic and therapeutic procedures. The objectives of this study are to describe the current pediatric procedural sedation and analgesia practice patterns in European emergency departments, to perform a needs assessment-like analysis, and to identify barr

Accident prediction models are often used to predict the number of accidents on segments and at intersections in the road network. Most often the models are developed for a total number of crashes for the facility, or crashes by severity. However, the frequency and severity of crashes of different types can be expected to vary with regards to the underlying phenomena that cause them to occur. To b

Popular Abstract in Swedish Vad är det för något i human mjölk som dödar cancer celler? Kan “fel” veckade proteiner vara nyttiga? Kan fett vara inblandat i protein veckning? Det är några av frågorna som tas upp i denna avhandling. Allt levande består av proteiner som i sin tur är uppbyggda av amino syror. Det finns 20 st. olika amino syror som på olika sätt kan länkas samman till proteinkedjor. DBy varying its secondary or tertiary structure a single protein can attain new biological functions. The amyloid forming proteins are the best known examples where a change in conformation leads to the formation of amyloid fibrils that accumulate in tissues and cause disease. a-lactalbumin in contrast, is an example of a protein that acquires a beneficial function when the conformation is altered

The active site of sulfite reductase (SiR) consists of an unusual siroheme–Fe4S4 assembly coupled via a cysteinate sulfur, and serves for multi-electron reduction reactions. Clear explanations have not been demonstrated for the reasons behind the choice of siroheme (vs. other types of heme) or for the single-atom coupling to an Fe4S4 center (as opposed to simple adjacency or to coupling via chains

BACKGROUND: Hair cosmetics such as hair dyes, bleaching, waving, and cleansing products are composed of numerous chemical ingredients. Allergic reactions to these contact allergens, other than p-phenylenediamine, are rarely reported.OBJECTIVES: To study the incidence of patch test reactions to hair cosmetic allergens and identify the factors associated with hair cosmetic allergy in Thailand.METHOD

Feedbacks mechanisms are essential components of our climate system, as they either increase or decrease changes in climate-related quantities in the presence of external forcings. In this work, we provide the first quantitative estimate regarding the terrestrial climate feedback loop connecting the increasing atmospheric carbon dioxide concentration, changes in gross primary production (GPP) asso

The interaction of blood coagulation factor X and its Gla-containing fragments with negatively charged phospholipid membranes composed of 25 mol% phosphatidylserine (PtdSer) and 75 mol% phosphatidylcholine (PtdCho) was studied by surface plasmon resonance. The binding to 100 mol% PtdCho membranes was negligible. The calcium dependence in the membrane binding was evaluated for intact bovine factor

The effects of data uncertainty in applications of the critical loads concept were investigated on different spatial resolutions in Sweden and northern Czech Republic. Critical loads of acidity (CL) were calculated for Sweden using the biogeochemical model PROFILE. Three methods with different structural complexity were used to estimate the adverse effects of SO2 concentrations in northern Czech R

This thesis demonstrates the usefulness of sedimentary pigments as biomarkers of environmental change in estuarine systems and as biomarkers in lakes in relation to climate change. These are two fields where sediment pigment records as measured by high-performance liquid chromatography (HPLC) are emerging areas of study. A detailed study was undertaken to examine the effects of different storage o

Untitled ANNUAL REPORT  INTER ARTS CENTER | FACULTY OF FINE AND PERFORMING ARTS Contents 1 | Welcome ......................................................................................................................... 3 2 | About .............................................................................................................................. 4 3 | Brief facts ................

https://www.iac.lu.se/sites/iac.lu.se/files/2025-04/IAC_report_2024_WEBPAGE.pdf - 2026-05-09

Antigenic diversity in pathogenic microbes can be a result of at least three different processes: diversifying selection by acquired immunity, host–pathogen coevolution and/or host specialization. Here, we investigate whether host specialization drives diversity at ospC (which encodes an immunodominant surface protein) in the tick-transmitted bacterium Borrelia afzelii. We determined prevalence an

Accident prediction models are often used to predict the number of accidents on segments and at intersections in the road network. Most often the models are developed for a total number of crashes for the facility, or crashes by severity. However, the frequency and severity of crashes of different types can be expected to vary with regards to the underlying phenomena that cause them to occur. To b

During the course of this three-year project, we have studied aeolian deposits at 70 sites within sixteen areas in south-central Sweden. Inland dunes have been the focus, but some sites with coversand and coastal dunes have also been investigated. We have mapped dune morphology, mainly by LiDAR-based remote sensing, studied the internal sediment architecture by ground-penetrating radar profiling a

Mangroves provide numerous environmental benefits, such as carbon sequestration, water purification, climate change mitigation, and flood and Tsunami impact reduction. Despite these unique advantages, mangroves are threatened by the combined adverse impacts of human activities and climate change. Therefore, it is essential to implement reasonable practices to avoid further degradation of mangroves

While the so-called “end of public space” literature, focusing on encroachment of private interests and state surveillance, has contributed to critical thinking of access (or the lack thereof) to public space, and the loss of publicity of public space, the conceptual tools such literature offers to understand contestations in and over public space have remained underdeveloped or, at best, underexp

Stability is a fundamental property affecting function, activity, and regulation of biomolecules. Stability changes are often found for mutated proteins involved in diseases. Stability predictors computationally predict protein-stability changes caused by mutations. We performed a systematic analysis of 11 online stability predictors' performances. These predictors are CUPSAT, Dmutant, FoldX, I-Mu

Reliable information on solar activity over the Holocene period is important to predict the Sun in the future and to understand the mechanism behind the Sun-climate linkage. Presently, there are discrepancies in the proxy data of solar activity due to reasons that are not yet understood. This leads to major uncertainties in Holocene solar reconstructions. This PhD project aims to improve the Holoc

Matching habitat choice is a habitat preference mechanism based on self-assessment of local performance, such that individuals settle in the habitats that are best suited to their phenotypes, promoting local adaptation. Despite the important evolutionary implications of matching habitat choice, examples from natural populations are rare. One possible reason for this apparent rarity is that phenoty

Vad spelar Arktis för roll i klimatförändringarna? Denna avlägsna, och glest befolkade, del av världen utgör faktiskt en viktig del av klimatsystemet. Arktis spelar en betydande roll i kolets kretslopp; vilket innefattar såväl koldioxid och metan, två av de viktigaste växthusgaserna. Förändringar i koncentrationer av växthusgaser påverkar hur mycket värme som hålls kvar i jordens atmosfär. VåtmarkMethane is one of the most important greenhouse gases, and the Arctic region plays an important role in its dynamics. Due to limited observations in this remote and often harsh environments, large uncertainties surround the role of the Arctic region in a warming climate. In this thesis, I examine the performance of the three low-cost solid state sensors, Figaro sensors TGS2600-B00, TGS2611-C00 an

3D-modeller är grunden i det som kallas BIM och är något som används mer flitigt inom byggbranschen men desto mindre inom anläggningsprojekt. BIM har utvecklats mer och mer för att underlätta samordningen av flera aktörer och lösa konflikter i olika faser och skeden. Med ytterligare dimensioner integreras även tid och kostnadsaspekten på projektet som resulterar i ett mer produktivt byggande. Gru3D-models are the base of what is called BIM. It is used more and more within in the construction industry over all, but not as much in the field of infrastructure projects. BIM is developed to coordinate several actors and resolve conflicts in different phases of the construction. With dimensions integrated in the model, such as time and cost aspect, it result in a more productive project. The m