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Background: A significant proportion of patients with asthma have persistent symptoms despite treatment with inhaled glucocorticosteroids. Objective: We hypothesized that in these patients, the alveolar parenchyma is subjected to mast cell-associated alterations. Methods: Bronchial and transbronchial biopsies from healthy controls (n = 8), patients with allergic rhinitis (n = 8), and patients with
The nervous system is constantly infiltrated by blood-derived sentinels known as perivascular macrophages. Their immediate precursors have not yet been identified in situ and the mechanism that governs their recruitment is mostly unknown. Here, we provide evidence that CD68 (+)GR(-) monocytes can give rise to perivascular macrophages in mice suffering from endotoxemia. After adhesion to the endoth
Disturbed haemostasis is a central finding in severe Streptococcus pyogenes infection. In particular, microthrombi are found both at the local site of infection and at distant sites. Platelets are responsible for maintaining vascular function and haemostasis. We report here that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation. M1 protein is released fr
Popular Abstract in Swedish Vår forskningsgrupp har tidigare påvisat kraftiga förändringar i genuttryck för neurotrofiner, en familj av tillväxtfaktorer för nervceller, och deras receptorer i kortikala och hippokampala nervceller vid olika hjärnskador. Det är till stora delar okänt vilken funktion neurotrofiner har efter hjärnskador, men neurotrofinsvaret skulle kunna vara en skyddande mekanism ocThis study explores the role of brain-derived neurotrophic factor (BDNF) for neuronal vulnerability and neurogenesis following cerebral ischemia in the rat. Cerebral ischemia results in selective neuronal cell loss in specific brain regions. We here demonstrate the rank order of vulnerability in two regions affected by global forebrain ischemia, i.e., hippocampus and striatum, by combining specifi
A dry release method for fabrication of suspended nanostructures is presented. The technique has been combined with an anti-stiction treatment for fabrication of nanocantilever based nanoelectromechanical systems (NEMS). The process combines a dry release method, using a supporting layer of photoresist which is removed using oxygen ashing in a reactive ion etcher (RIE), with CHF3 plasma induced de
Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.
STRATEGISK MILJÖUTVECKLING (MVET11) MILJÖVETENSKAP Preliminärt schema 170619 Kurs: MVET II Kursansva Bernadett Kiss; Julia Nussholz Lärare: Bernadett Kiss (BK), Julia Nussholz (JN), Andrius Plepys (AP), Sofie Sandin (SS), Peter Arnfalk (PA), Matthias Lehner (ML), Jessika Luth Richter (JLK) Lokaler: Raggmossan, Ekologihuset, Sölvegatan 37. Litteratur: see additional file Studieteknik: Läs om studie
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schedule_mvet_ii_ht17_1.pdf - 2026-07-01
The author examines the intriguing mention of “those who curse Yamm” and “rouse Leviathan” in Job 3:8, and tries to relate these expressions to Near Eastern religious history. The old assumption that two texts inscribed on Aramaic incantation bowls indicate the full background of these expressions is challenged, and further evidence is sought in texts such as the Enuma Elish, the Gnosticizing “Hym
Fjalldal S, Rylander L, van Westen D, Holmer H, Follin C, Gabery S, Petersen Å and Erfurth E M. Clinical Endocrinology (Oxf). 94(1): 48-57 (2021) Abstract Context: White matter lesions (WML) are caused by obstruction of small cerebral vessels associated with stroke risk. Craniopharyngioma (CP) patients suffer from increased cerebrovascular mortality. Objective: To investigate the effect of reduced
Holiday season 2025/2026 During the Christmas, New Year and Epiphany holidays, the joint service functions at Kemicentrum will have the following opening hours.Library and Information desk22 December: 09:00–15:0023 December – 6 January: Closed (Unstaffed)Read more about 'Unstaffed hours' on the Library of Science’s website.Regular opening hours resume from 7 January.Caretaker’s officeDecember 24–2
https://www.kc.lu.se/en/holiday-opening-hours-joint-services - 2026-07-01
Professor | Principal investigator BECC | Excellent Teaching Practitioner Contact details Email: fariborz [dot] zelli [at] svet [dot] lu [dot] se Phone: +46 46 222 47 64Organisation Department of Political Science Room number: 330 Service point: 31 WebpageFariborz Zellis profile in Lund University research portalOther affiliations Member of Strategic Research Area BECC: Biodiversity and Ecosystem
https://www.svet.lu.se/en/fariborz-zelli - 2026-07-01
The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was
