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Inhibition of dipeptidyl peptidase-4 augments insulin secretion in response to exogenously administered glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide, pituitary adenylate cyclase-activating polypeptide, and gastrin-releasing peptide in mice

Inhibition of dipeptidyl peptidase- 4 ( DPP- 4) is currently being explored as a new approach to the treatment of type 2 diabetes. This concept has emerged from the powerful and rapid action of the enzyme to inactivate glucagon- like peptide-1 ( GLP- 1). However, other bioactive peptides with potential influence of islet function are also substrates of DPP- 4. Whether this inactivation may add to

Echocardiographic and electrocardiographic identification of those children with hypertrophic cardiomyopathy who should be considered at high-risk of dying suddenly

Background., Hypertrophic cardiomyopathy is a common cause of sudden death in children. In this study, we aimed to identify clinical measures for stratification of this risk in childhood. Patients and methods: By means of a retrospective cohort study from six regional centres of paediatric cardiology, we identified 128 patients with hypertrophic cardiomyopathy presenting below 19 years of age, wit

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Transmission problems and domain decompositions for non-autonomous parabolic equations on evolving domains Amal Alphonse, Ana Djurdjevac, Emil Engström, and Eskil Hansen Abstract. Parabolic equations on evolving domains model a multitude of applications including various industrial processes such as the molding of heated materials. Such equations are numerically challenging as they require large-s

https://www.maths.lu.se/fileadmin/maths/personal_staff/Eskil_Hansen/Evolving_DDM.pdf - 2026-06-02

Salary, Benefits and Competence development

Salary, Benefits and Competence development | Akademikerföreningen at Scania and TRATON Hoppa till huvudinnehåll Join us Here's why We are members GDPR and how we process personal data Become a trustee Contact person Safety officer Member of the Board Member of the Election Committee Auditor Roadmap and initiatives Roadmap Work environment Salary, Benefits and Competence development Transformation

https://www.saco.se/en/trustee/local-union-work/local-unions/private-sector/akademikerforeningen-at-scania/roadmap-and-initiatives/roadmap/compensations/ - 2026-06-02

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Nyhetsbrev från Akademikerföreningen Sveriges Ingenjörer vid Siemens Energy AB Kontakt: asi.se@siemens-energy.com Redaktörer: CH, JB Nr: 03 2025-04-01 Pension – ditt livs längsta after work Pensionen kan kännas väldigt avlägsen och något som du kan börja tänka på senare, men det lönar sig att ha din pension i åtanke genom hela din yrkeskarriär. Glöm inte att pensionen är den lön du får när du slut

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/siemens-energy-ab/nyhetsbrev/asi-nyhetsbrev-0325.pdf - 2026-06-02

Fuentes A et al SDGs localization in Sweden - Research Brief

Fuentes A et al SDGs localization in Sweden - Research Brief RESEARCH & POLICY BRIEF July 2021 LOCALISATION PROCESS OF SDGs AND HUMAN RIGHTS IN SWEDEN Framework Agreements and Idea-Driven Partnerships 2 ISBN 978-91-86910-48-8 3 Research & Policy Brief Authors Dr. Alejandro Fuentes, David Eile, Alice Kasznar, and Astrid Aigrot Ramsay, Raoul Wallenberg Institute of Human Rights and Humanitarian Law

https://rwi.lu.se/wp-content/uploads/2021/12/Fuentes-A-et-al-SDGs-3-FINAL.pdf - 2026-06-02

HPV testing, methylation and genotyping in cervical cancer screening and treatment follow-up

HPV testing has a higher sensitivity than cytology for identification of women at risk of cancer. Primary HPV testing was introduced in the organized screening program in Skåne, Sweden in 2017 for women 30 years and older. High-risk HPV E6/E7 mRNA was detected in 7.0% of these women. Primary HPV-screening identified a similar proportion of abnormal cytology (ASCUS+) as cytology-based screening (3.

High titers of neutralizing SARS-CoV-2 antibodies six months after symptom onset are associated with increased severity in COVID-19 hospitalized patients

BACKGROUND: Viral shedding and neutralizing antibody (NAb) dynamics among patients hospitalized with severe coronavirus disease 2019 (COVID-19) and immune correlates of protection have been key questions throughout the pandemic. We investigated the duration of reverse transcriptase-polymerase chain reaction (RT-PCR) positivity, infectious viral shedding and NAb titers as well as the association be

Real-world outcomes with ibrutinib in relapsed or refractory mantle cell lymphoma : a Danish population-based study

Ibrutinib was approved for relapsed/refractory (R/R) mantle cell lymphoma (MCL) based on high response rates in clinical trials, but it is unclear how effective ibrutinib is in the real-world setting. This study provides population-based response rates and survival estimates and characterization of prognostic indicators and adverse events (AEs) to ibrutinib for patients with R/R MCL. All patients

Motion and Eddy-Current Correction in Diffusion MRI

Subject motion and eddy-current distortions represent significant challenges in diffusion MRI, particularly for clinical protocols utilizing "half-sphere" sampling. While the current gold standard, FSL’s eddy, employs Gaussian Process (GP) predictions to correct these artifacts, its performance can degrade under specific acquisition constraints, most notably when sampling lacks antipodal

Cerebral near-infrared spectroscopy monitoring for prevention of death or neurodevelopmental disability in very preterm infants

RATIONALE: Very preterm infants (i.e. born before 32 weeks of gestation) are at risk of cerebral injury and long-term neurodevelopmental impairment. Cerebral near-infrared spectroscopy (NIRS) enables continuous monitoring of cerebral oxygenation to guide clinical management. Interest in NIRS has grown in recent years, highlighting the need for better evidence to support its clinical efficacy in im

Are JAKis more effective among elderly patients with RA, smokers and those with higher cardiovascular risk? A comparative effectiveness study of b/tsDMARDs in Sweden

OBJECTIVES: To investigate whether the relative effectiveness of janus kinase inhibitors (JAKis) versus tumour necrosis factor inhibitors (TNFi) or other biological disease-modifying antirheumatic drugs in rheumatoid arthritis differ by the presence or absence of risk factors for cardiovascular (CV) disease, age, sex and smoking. METHODS: Through Swedish registers, we identified 13 493 individuals

Face temperature and cardiorespiratory responses to wind in thermoneutral and cool subjects exposed to -10 °C

The effects of the thermal state of the body (slightly cool and neutral) and moderate wind speeds on face temperature, blood pressure, respiratory function and pain sensation during cold exposure were studied on eight healthy male subjects. They were dressed in cold-protective clothing and preconditioned at +20 °C (TN) and m5 °C (CO) for 60 min, then exposed to m10 °C and 0 m · sm1 (NoW), 1 (W1) a

Acute pancreatitis - Cellular response and dynamic inflammatory changes

Popular Abstract in Swedish Akut pankreatit (bukspottkörtelinflammation) drabbar årligen cirka 300 individer per miljon invånare i Sverige. Dödligheten ligger totalt på cirka 4-7 % och betydligt högre, cirka 20 %, vid svår nekrotiserande pankreatit. Mortaliteten är vanligen associerad med multipel organsvikt och korrelerad till storleken på det inflammatoriska svaret. Underliggande mekanismer för Acute pancreatitis (AP) is a common disorder where underlying mechanisms for the local initiating events in the pancreas, the systemic dissemination of the inflammatory response and the remote organ dysfunction still are unclear. The aim of the present study was to further characterize the dynamics and sequence of the immune response in AP, and to determine the cellular origin of the initiating ev

Heterogeneity in the growth of the axial and appendicular skeleton in boys : Implications for the pathogenesis of bone fragility in men

Men with spine fractures have reduced vertebral body (VB) volume and volumetric bone mineral density (vBMD). Men with hip fractures have reduced femoral neck (FN) volume and vBMD, site-specific deficits that may have their origins in growth. To describe the tempo of growth in regional bone size, bone mineral content (BMC), and vBMD, we measured bone length, periosteal and endocortical diameters, B

Beräkning av orderkvantiteter i ny produktionsanläggning

Sandvik Rock Processing in Svedala is a business area within the Sandvik Group who manufactures crushers and spare parts. A new production plant, Greenfield, will be completed in 2013 and as part of the change the company makes in connection with the new plant, there is a desire to revise and optimize the order quantities in the production. There are several models for lot sizing. Economic Order Q

Spårväg i Helsingborg - En idéstudie och förprojektering av två spårvägslinjer mellan Trädgårdsgatan och Hälsovägen

This thesis is a combined conceptual study and preliminary design of two study options for a future tramway line between Trädgårdsgatan and Hälsovägen in Helsingborg. This line is of great interest since it’s centrally located and regarded as a problematic stretch of narrow streets, heavy traffic and steep gradients. In addition, a local tramway line in Helsingborg is regarded as a priority projec

Issues Around Bioprospecting, Traditional Knowledge and Access and Benefit Sharing in international and national legislation

Biodiversity was during the 1990s perceived as 'green gold'. With the emergence of the biotechnology industry, biodiversity prospecting, or bioprospecting, was perceived to provide opportunities to gain benefits for several purposes. Benefits would attribute towards conservation, development of source countries, new medicines, profits for the industry and welfare to local providers of biog

De nya takeover-reglerna - särskilt om prisskillnader mellan aktieslag med olika röstvärden

Den 1 oktober 2009 trädde en de nya Takeover-reglerna i kraft. Den största nyheten i de nya reglerna var den kraftigt minskade möjligheten att erbjuda röststarka aktier ett högre pris än röstsvaga aktier i ett offentligt uppköpserbjudande. Detta är en skärpning av den aktiemarknadsrättsliga likhetsprincipen och avsikten var att tillförsäkra minoritetsägare en större del av uppköpspremien. UppsatseThe 1 October 2009 new Takeover Rules entered into force. The most material change of the new rules was that they decreased the possibility to offer multiple voting shares a higher price than ordinary shares. This is a strengthening of the legal principle of equality as applied at the Nasdaq OMX Stockholm stock market. The intention was to ensure that minority shareholders got a greater share of t

The influence of ageing on the salt-frost resistance of concrete

Popular Abstract in Swedish Jämte korrosionsangrepp är skador på grund av saltfrostangrepp den vanligaste skadetypen hos betongkonstruktioner som utsätts för miljöer med fukt, salt och frost. Exempel på sådana miljöer är marina miljöer och tösaltade vägmiljöer. Betongens saltfrostbeständighet bestäms till stor del av betongsammansättningen, främst av förhållandet mellan mängden vatten och cement oAbstract This thesis presents the results of an investigation of the influence of ageing on the salt-frost resistance of concrete. The ageing mechanisms investigated were hydration, drying and carbonation. Specimens of ‘micro’-concrete, either with OPC alone as the binder or with silica or slag as part of the binder, were freeze/thaw tested at different ages after casting. Prior to testing, the sp