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High blood pressure (BP) is associated with cardiovascular morbidity and mortality. Both genetic and environmental factors are implicated in BP homeostatsis and hypertension development. The aims of the present theisis were: (a) to test if ambulatory BP (ABP) is better than office BP (OBP) to capture the heritable part of BP and if BP variability (BPV) measured by ABP monitoring is a heritable tra
Introduction Aniridia (iris more or less missing), is a congenital, dominant, inherited, serious and sight-threatening disease, most often appearing as an isolated eye disorder. It is caused by mutations in the PAX6 gene, the master gene of the development of the eye. Typically, Aniridia causes severe visual impairment. In addition to glare caused by the iris defect, underdevelopment of the macula
Background: Sweden is a high endemic region for multiple sclerosis (MS), a neurologic disorder characterized by repeated inflammatory episodes affecting the CNS. The disease has its peak age of onset at approximately 30 years and affects women twice as often as men. The young age of onset makes MS one of the major causes of reduced capacity to work due to neurologic disease in Western society. Nat
Brown C, Hasson H, Thyselius V, Almborg A-H. Post-stroke depression and functional independence: a conundrum. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2011.01595.x. © 2011 John Wiley & Sons A/S. Objectives - People who suffer a stroke are at risk of developing post-stroke depression (PSD). Not only does this lower their quality of life but it also increases their risk of another stroke or d
Objectives To describe clinical history and ultrasound findings in patients with tubal carcinoma. Methods Patients with a histological diagnosis of tubal cancer who had undergone preoperative ultrasound examination were identified from the databases of 13 ultrasound centers. The tumors were described by the principal investigator at each contributing center on the basis of ultrasound images, ultra
PURPOSE: To investigate whether separate physical tests of the lower extremities, that assess movement speed and postural control, were associated with cognitive impairment in older community-dwelling subjects. SUBJECTS AND METHODS: In this population-based, cross-sectional, cohort study, the following items were assessed: walking speed, walking 2 × 15 m, Timed Up and Go (TUG) at self-selected an
CONTEXT: The prevalence of obesity among adolescents has increased and we lack effective treatments. OBJECTIVE: To determine if gastric bypass is safe and effective for an unselected cohort of adolescents with morbid obesity in specialized health care. DESIGN, SETTING AND PATIENTS: Intervention study for 81 adolescents (13-18 years) with a body mass index (BMI) range 36-69 kg m(-2) undergoing lapa
Alcohol consumption may be associated with risk of colorectal cancer (CRC), but the epidemiological evidence for an association with specific anatomical subsites, types of alcoholic beverages and current vs. lifetime alcohol intake is inconsistent. Within the European Prospective Investigation into Cancer and Nutrition (EPIC), 478,732 study subjects free of cancer at enrolment between 1992 and 200
Objective: To evaluate the internal consistency of the Hip disability and Osteoarthritis Outcome Score-Physical Function Short-form (HOOS-PS) and the Knee injury and Ostecarthritis Outcome Score-Physical Function Short-form (KOOS-PS) in total hip replacement (THR) and total knee (TKR) replacement. Construct validity and responsiveness were compared to the Western Ontario McMaster Universities' Ost
The recombinant xylose-utilizing Saccharomyces cerevisiae TMB 3399 was constructed by chromosomal integration of the genes encoding Image-xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase (XK). S. cerevisiae TMB 3399 was subjected to chemical mutagenesis with ethyl methanesulfonate and, after enrichment, 33 mutants were selected for improved growth on Image-xylose and carbon dio
Popular Abstract in Swedish Alla levande organismer har DNA, och eftersom DNA är livsnödvändigt måste det repareras om det blir skadat. Ultraviolett (UV) strålning från solen är en av de vanligaste orsakerna till att DNA skadas. De flesta skador på DNA som orsakas av UV-strålning utgörs av cyklobutan-pyrimidindimerer (CPD) eller (6-4)-fotoprodukter. Dessa skador består av två intilliggande baser sAll living organisms have DNA and since DNA is essential to life it must be repaired when damaged. UV radiation is one of the major DNA damaging agents, which photosynthetic organisms cannot avoid. The major UV-induced DNA lesions are cyclobutane pyrimidine dimers (CPDs) and (6-4) photoproducts (6-4PPs) and the main repair pathways of theses lesions involve photolyases and various excision repair
Jämförande mätningar med olika typer av fotmodeller har genomförts. Åtta olika laboratorier deltog. Storleken på de olika modellerna motsvarade skostorlekar från 41 till 44. Sex andra laboratorier var intresserade att deltaga men kunde inte genomföra mätningar vid tillfället. En databas skapades som gör det möjligt att fortlöpande tillföra resultat från mätningar med typer av andra skodon samt vidA limited Round Robin test has been carried out with different types of foot models. Eight laboratories were able to carry out tests. The foot models varied in sizes from 254 mm to 275 mm, representing boot sizes from 41 to 44. Six other laboratories were interested but were not able to carry out the tests within this study. A database has been created. New test results from other test laboratorie
Migration patterns of Nordic Greylag Geese Anser anserwere studied by means of neck-collaring. A total of 4173birds (738 breeders, 1999 goslings and 1436 moulters;most moulters subsequently identified as belonging to aspecified breeding population) was marked throughoutNorway, Sweden, Denmark and Finland during 1984–1994. This report is based on observations made up to 30June 1995. In general, Nor
Background Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show pleiotropy; that is, they are also associated with other diseases or traits. Objectives This study sought to systematically test if genetic variants identified for non-CAD diseases/traits also associate with CAD and to undertake a comprehensive analysi
Popular Abstract in Swedish Potatis har varit, och är fortfarande ett viktigt baslivsmedel i svensk kosthållning. Det finns många sorter med olika egenskaper vilket bidrar till dess variationsrikedom. Potatisen är en rik källa till stärkelse, kostfibrer samt vitaminer och mineraler, t ex C-vitamin och järn. En invändning mot potatis ur nutritionell synvinkel är att stärkelsen lätt bryts ned av enzDespite decreased consumption potatoes still constitute an important staple in the Swedish diet. An objection to potatoes and potato products from a nutritional point of view is the ease by which the starch is digested and absorbed in the gastrointestinal tract. This results in unfavourably high glycaemic and insulinaemic responses (glycaemic index, GI and insulinaemic index, II, respectively). Su
Improved environmental consciousness and harsh legislation concerning volatile organic compounds (VOCs) during the 1980s led to an increase in the development in the field of polymer colloids. Solvent born coatings were replaced by polymer dispersions in aqueous solution, so called latex dispersions. As a consequence, numerous research programs concerning polymerization processes (e.g. emulsion po
The purpose of the research presented in this thesis is to enhance the field of accessibility to include a multitude of perspectives. Based on cultural-historical activity theory (CHAT), it analyzes how human, artifactual and natural factors impact an individual’s possibilities to act in concrete situations that are part of a systemic whole.The thesis presents two main results:An enhanced accessib
Popular Abstract in Swedish Ovan jord & under ytan Sandstäpp är en hotad växtmiljö eftersom arealen av sandstäpp minskat avsevärt sedan Linnés tid (1700-talet). Vi ställde oss frågan varför den har minskat. För att kunna besvara den måste vi förstå vad växtarterna behöver och förstå hur kemin i marken fungerar. Dessutom vill vi lära oss hur markens organismer påverkas av minskningen av sandstSandy, calcareous grasslands are species rich temperate semi-natural grasslands. The species composition in 136 plots was analysed in relation to soil chemistry parameters; extractable P and N, soil pH and lime content. We found that that acidification and decalcification decrease species diversity and the number of red-listed species in these sandy grasslands. The microbial community was investig
Abstract Title: Employees’ experiences of working remotely from home during the covid-19 pandemic - a mixed method study at Försäkringskassan Author: Lina Dahlberg Supervisor: Jan Mewes, Lund University Sweden Course: SOCM03 Master thesis course, Master of Science in Human Resource Development and Labour Relations, 30 credits. Department of Sociology, spring 2021 Background & aim: The uni
