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Bladder exstrophy : Clinical and experimental aspects

Popular Abstract in Swedish Blåsexstrofi är en ovanlig och mångfasetterad missbildning. I hela Sverige föds cirka tre barn om året med blåsexstrofi. Bukvägg och urinblåsa är öppna nedanför naveln, så att man ser blåsans insida samt rinnande urin. Flickorna har en delad clitoris, framflyttad och trång slidöppning samt framflyttad ändtarmsöppning. Pojkarna har en kort, öppen penis, som ligger uppfäl

Visualization and understanding of combustion processes using spatially and temporally resolved laser diagnostic techniques

Laser diagnostic techniques have for more than 30 years added very valuable input for a deepened understanding of combustion processes. The present paper will focus on techniques developed for visualization of important parameters with the ability to get detailed information in space and time. The paper is not meant to be a complete review of the entire research field but rather a survey with a ma

Subduction controls on Miocene back-arc lavas from Sierra de Huantraico and La Matancilla and new Ar-40/Ar-39 dating from the Mendoza Region, Argentina

Back-arc volcanism in the western Argentinian provinces of Mendoza and Neuquen has been widespread from the Miocene to historic times. We present a detailed investigation of profiles through two of the major Miocene volcanic areas of the region, the neighboring Huantraico and La Matancilla plateaus, including new Ar-40/Ar-39 age results of major and trace elements as well as Nd, Sr and Pb isotopic

BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential.

Triple negative (TN) breast cancers make up some 15% of all breast cancers. Approximately 10-15% are mutant for the tumor suppressor, BRCA1. BRCA1 is required for homologous recombination-mediated DNA repair and deficiency results in genomic instability. BRCA1-mutated tumors have a specific pattern of genomic copy number aberrations that can be used to classify tumors as BRCA1-like or non-BRCA1-li

How substantial are ultraviolet-B supplementation inaccuracies in experimental square-wave delivery systems?

Square-wave (SQW) ultraviolet-B (UV-B: 280–315 nm) radiation supplementation systems continue to be used in outdoor experimental locations due to the economically restrictive installation and maintenance costs, and technical expertise required to effectively operate more advanced modulated (MOD) delivery systems. However, continued yet contentious criticisms of SQW delivery systems risk creating p

Microbial activity in soils frozen to below-39 degrees C

Recent research on life in extreme environments has shown that some microorganisms metabolize at extremely low temperatures in Arctic and Antarctic ice and permafrost. Here, we present kinetic data on CO2 and (CO2)-C-14 release from intact and C-14-glucose amended tundra soils (Barrow, Alaska) incubated for up to a year at 0 to -39 degrees C. The rate of CO2 production declined exponentially with

On the Relations between Driving Patterns, Exhaust Emissions and Network Characteristics in Urban Driving

Popular Abstract in Swedish Bakgrund Hur gatunätet ser ut och planera's i städer påverkar förutom trafikarbetet även hur bilister kör. Körbeteendet i form av körmönster, d.v.'s. hastighet's- och accelerationsprofiler, påverkar i sin tur såväl bränsleförbrukning som avgasemissionsfaktorer. En betydande del av trafiken sker inom tätorter där såväl luftkvalitet som totala utsläpp är av betydelse. ÄvThe planning and design of street networks in cities influence driving behaviour and give rise to variations in driving patterns (i.e., speed and acceleration profiles) that affect exhaust emissions and fuel consumption. The primary objective of this study has been to use real-life driving patterns to investigate how the characteristics of street networks influence fuel consumption and vehicular e

Testing in serum for human glandular kallikrein 2, and free and total prostate specific antigen in biannual screening for prostate cancer.

Purpose: We investigated the value of serum measurements for glandular kallikrein 2 (hK2), and free (f) and total (t) prostate specific antigen (PSA) in a second round of biannual screening for prostate cancer. Materials and Methods: In 1995 to 1996, 5,853 of 9,811 randomly selected men in Goteborg, Sweden 50 to 66 years old had PSA measurements. Of 660 men 611 with tPSA 3 ng/ml or greater underwe

A set-up for field studies of respiratory tract deposition of fine and ultrafine particles in humans

Respiratory tract deposition data of ultrafine aerosol particles, hygroscopic particles and ambient particles in general are scarce. Measurements are associated with several difficulties. The objective of this work was to design a method for fast determination of highly size-resolved fine and ultrafine particle deposition, to be used on larger groups of human subjects in exposure studies and in ty

Inconsistency between glycemic and insulinemic responses to regular and fermented milk products

Background: Foods with a low glycemic index are increasingly being acknowledged as beneficial in relation to the insulin resistance syndrome. Certain organic acids can lower the glycemic index of bread products. However, the possible effect of acids in fermented milk products on the glycemic index and on insulinemic characteristics has not been addressed. The metabolic effects of fermented milk or

Talet om det mångkulturella i skolan och samhället : En analys av diskurser om det mångkulturella inom utbildning och politik åren 1973-2006

Popular Abstract in Swedish Talet om det mångkulturella i skolan och samhället: En analys av diskurser om det mångkulturella inom utbildning och politik åren 1973-2006 Det svenska samhället har under de senaste tre decennierna påverkats av debatter, rapporteringar och diskussioner om det mångkulturella samhället. Frågan om hur man ska handskas med ?det mångkulturella? har uppfattats och beskrivitThe debate on "multicultural issues" has had a considerable impact on society, and in Sweden, dealing with such issues has been described and defined as a major problem. The aim of the present thesis is to analyse the various contents of discourses on multicultural issues that have influenced education and policy documents during the period 1973-2006. On several occasions, the Swedish government h

Thermo-economic evaluation of bio-ethanol humidification EvGT cycle

The evaporative gas turbine pilot plant (EvGT) has been in operation at Lund Institute of Technology in Sweden since 1997. This article presents the latest development in the evaporative technology, the evaporation of bio-ethanol in a gas turbine power plant as a means to reduce the emission of greenhouse gases. Bio-ethanol is produced from a feedstock consisting of corn-stover, and the bio-ethano

Chronic Helicobacter pylori infection in a population in southern Sweden analysed by histopathology, immunoblot and ELISA serology.

Background. Many individuals are infected with the bacterium Helicobacter pylori. Some develop ulcers or mucosal atrophy. Aims. To correlate the histological characteristics of the H. pylori-induced gastritis to the immunoblot pattern of the H. pylori infection and to compare the presence of H. pylori bacteria in tissue specimens with ELISA serology and immunoblot analysis. Methods. One hundred an

Effects of buffering in hypercapnia and hypercapnic hypoxemia

Anesthetized, paralyzed and mechanically ventilated pigs were exposed to extreme hypercapnia (PaCO2 approximately 20 kPa) at FiO2 0.4 for 480 min, with (n = 6) or without (n = 6) continuous infusion of isotonic buffers (bicarbonate and trometamol). Arterial pH was higher in buffered animals than controls, 7.21 +/- 0.01 vs 7.01 +/- 0.01 (mean +/- s.e.mean, P < 0.01). Serum osmolality and PaCO2 did

Body size and breast cancer risk: Findings from the european prospective investigation into cancer and nutrition (EPIC)

The evidence for anthropometric factors influencing breast cancer risk is accumulating, but uncertainties remain concerning the role of fat distribution and potential effect modifiers. We used data from 73,542 premenopausal and 103,344 postmenopausal women from 9 European countries, taking part in the EPIC study. RRs from Cox regression models were calculated, using measured height, weight, BMI an

Nocturnal pulse wave attenuation is associated with office blood pressure in a population based cohort

Objective and Background: Pulse wave amplitude (PWA) derived from the digital vascular bed has been used in sleep studies. The nocturnal attenuation of PWA has been shown to reflect sympathetic activation during sleep. We assessed the relationship between nocturnal PWA attenuation and office blood pressure (BP). Methods: Eighty-one subjects (46 men; age 60 7 years: body mass index [BMI] 28.2 +/- 4

Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease.

In an attempt to define clinically relevant models of akinesia and dyskinesia in 6-hydroxydopamine (6-OHDA)-lesioned rats, we have examined the effects of drugs with high (L-DOPA) vs. low (bromocriptine) dyskinesiogenic potential in Parkinson's disease on three types of motor performance, namely: (i) abnormal involuntary movements (AIMs) (ii) rotational behaviour, and (iii) spontaneous forelimb us

PRETERM BIRTH AND RISK OF MEDICALLY TREATED HYPOTHYROIDISM IN YOUNG ADULTHOOD.

Objective: Previous studies suggest that low birth weight is associated with thyroid autoimmunity and hypothyroidism in later life, but the potential effect of preterm birth, independent of fetal growth, is unknown. Our objective was to determine whether preterm birth is independently associated with medically treated hypothyroidism in young adulthood. Design/Participants: National cohort study of

Män, våld och moralarbete : Rapporter från män som sökt behandling för våld i nära relationer

Popular Abstract in Swedish I Män, våld och moralarbete uppmärksammas hur män, som frivilligt sökt sig till verksamheter där det erbjuds behandling för våld i nära relationer, rapporterar om sina erfarenheter. Rapporteringarna består dels av svar på frågeformulär, dels genom deltagande i samtalsintervjuer. Författaren analyserar hur männen förklarar sina handlingar och gestaltar återberättade erfaMen, violence and moral work- Reports from help-seeking men at treatment centers working with violence in close relationships Men’s violence against women is an extensive social problem. In the 1970s, a new kind of centers were established in the US and UK, focusing on treating men who had been violent against their wives or girlfriends, the aim which is to end the men’s violent behavior. In the

Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmo Preventive Project).

Aims Orthostatic hypotension (OH) has been linked to increased mortality and incidence of cardiovascular disease in various risk groups, but determinants and consequences of OH in the general population are poorly studied. Methods and results Prospective data of the Swedish 'Malmö Preventive Project' (n = 33 346, 67.3% men, mean age 45.7 +/- 7.4 years, mean follow-up 22.7 +/- 6.0 years) were analy