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Objective: To obtain experiences and expert opinion on treatment of SSc patients with TNF-alpha antagonists. Methods: An investigation was carried out among the EUSTAR centres into their expertise on use of TNF-alpha antagonists. Assessment forms on the frequency of TNF-alpha inhibitor use were distributed to EULAR Scleroderma Trials and Research Group (EUSTAR) centres. Afterwards, a three round D
Obese subjects have increased number of enlarged fat cells which are reduced in size but not number in post-obesity. We performed DNA methylation profiling in fat cells with the aim of identifying differentially methylated DNA sites (DMS) linked to adipose hyperplasia (many small fat cells) in post-obesity.
Aims/hypothesis Our aim was to investigate the association between birthweight and latent autoimmune diabetes in adults (LADA), a common diabetes form with features of both type 1 and type 2 diabetes. Methods We used data from the Epidemiological Study of Risk Factors for LADA and Type 2 Diabetes (ESTRID), a Swedish population-based study. Eligible for the analysis were 134 incident LADA cases (gl
This paper examines how the International laws of, in and after war are, as a Schmittian political theology, instructed by a Christian eschatological concept of time. The paper uncovers how Christian remnants are present in both international law and in our Nordic societies, suggesting that we ought to consider carefully how our understanding and narration of time is furthering the eschatological
Clothing evaporative resistance is one of the inherent factors that impede heat exchange by sweating evaporation. It is widely used as a basic input in physiological heat strain models. Previous studies showed a large variability in clothing evaporative resistance both at intra-laboratory and inter-laboratory testing. The errors in evaporative resistance may cause severe problems in the determinat
A genome-wide linkage analysis to identify quantitative trait loci (QTLs) for bone phenotypes was performed in an F-2 intercross of inbred spontaneously type 2 diabetic GK and normoglycemic F344 rats (108 males and 98 females). The aim of the study was to locate genome regions with candidate genes affecting trabecular and cortical bone and to investigate the effects of sex and reciprocal cross. pQ
BACKGROUND: Neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and total-tau protein (tau) are novel blood biomarkers of neurological injury, and may be used to predict outcomes in critical COVID-19.METHODS: A prospective multicentre cohort study of 117 consecutive and critically ill COVID-19 patients in six intensive care units (ICUs) in southern Sweden between May and Novem
Urban infrastructure is crucial for livelihoods and economic growth, however, access remains fragmented. Such differential infrastructure provision within cities necessitates intra-urban comparison and a renewed commitment to re-thinking between and within neighborhoods in ways that do not universalize infrastructure geographies. This paper examines how electricity and water infrastructure affect
Background: Obesity and type 2 diabetes (T2DM) are considered risk factors for complications following total hip arthroplasty (THA). How these risk factors separately or in combination influence the risk of reoperation due to periprosthetic joint infection (PJI) or all-cause reoperation is not fully known. We sought to investigate the 2-year risk of reoperation following THA due to osteoarthritis
Background: With this study, we aim to explore pre-operative probabilistic expectations (what does the patient realistically expect) and value-based expectations (what does a patient consider important), post-operative expectation fulfillment, and the relationship with post-operative satisfaction in shoulder arthroplasty (SA) patients. We hypothesized that higher expectation fulfillment is related
Antidumping is a burning topic that has been lively debated lately. The usage of antidumping has enhanced during the past decade and affects the trade flow between countries. In this thesis antidumping procedures are investigated and effects on antidumping measures are analysed and discussed. All antidumping targeted footwear has been included in the investigation. The products originate from Chin
Many studies have tried to explain the stock market value premium identified by Fama and French and Rosenberg, Reid and Lanstein. To the proponents of conventional asset pricing theory the value premium, measured by HmL (high book-to-market minus low book-to-market), is a bit of a dilemma. This is due to that the value of growth stocks depend more on business cycles than on value stocks, whose val
Background: Observational data on composite scores often comes with missing component information. When a complete-case (CC) analysis of composite scores is unbiased, preferable approaches of dealing with missing component information should also be unbiased and provide a more precise estimate. We assessed the performance of several methods compared to CC analysis in estimating the means of common
BACKGROUND: This systematic review aims to determine the loads of anti-A and anti-B in plasma-containing blood products that can safely be transfused to adults.MATERIALS AND METHODS: A comprehensive literature search was performed in PubMed, including studies dating back to 1940 until January 1 st, 2023. In total 1,869 articles were screened, describing 86 cases of hemolytic transfusion reactions
This paper explores the intersection of corporate sustainability and recruitment perspectives in Swedish companies, examining the use of one hundred and seven sustainability keywords in more than 230 000 IS/IT job ads collected from the Swedish Public Employment Service. The study emphasizes the pressing need for a new breed of computing professionals to address environmental challenges and climat
A low eGFRcystatin C/eGFRcreatinine-ratio is characteristic of a group of serious kidney disorders called ‘Selective Glomerular Hypofiltration Syndromes’. This study examines if such a low ratio can also be used to evaluate the risk for women with hypertensive disorders in pregnancy to develop severe maternal morbidity. All women discharged from the perinatal ward at the Skåne University Hospital
BACKGROUND: Unemployment is high not only among people with mental illness, but also among young adults in general. The combination of having a severe mental illness and being young entails a particularly problematic situation for young people with psychosis. This study aimed to understand how this group envision their future possibilities for entering the labour market or engaging in other produc
When Iran directed over 300 missiles and drones at Israel on April 13, Jordan helped fend off the attack. Initial media reports suggested that several other Arab states assisted in Israel’s defense, efforts they later denied. Nonetheless, a chorus of Israeli leaders, as well as some observers in Washington, interpreted these acts as a sign of a major shift. These Arab states, the argument went, wo
