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Plasma VEGF-D and sFLT-1 are potential biomarkers of hemodynamics and congestion in heart failure and following heart transplantation

BackgroundInflammation and tyrosine-kinases are known mediators in the pathobiology of cardiovascular disease. Plasma biomarkers reflecting these systems may provide a noninvasive complement reflecting hemodynamics, aiding in clinical decision-making. We therefore aimed to investigate the plasma levels of vascular and inflammatory proteins, and their associations with invasive hemodynamics in adva

TREM2 risk variants and associated endophenotypes in alzheimer’s disease

Background: Rare variants of the triggering receptor expressed on myeloid cell 2 (TREM2) gene are strong risk factors for Alzheimer’s disease (AD), and drugs targeting the TREM2 protein are being developed. However, it is unknown what the effect of TREM2 variants is on the AD phenotype. Methods: Here we studied a full range of clinical and biomarker measures in a large cohort of TREM2 variant carr

Extra-uterine placental transfusion and intact-cord stabilisation of infants in caesarean sections : an intervention development and pilot-study (INTACT-1)

Background: Keeping the umbilical cord intact the first minutes after delivery is beneficial for both term and preterm infants. However, this may be challenging in caesarean sections (CS) due to lack of mobile resuscitation equipment, maintenance of sterility or concern for excessive maternal blood loss. The objective of this study was to develop and pilot-test extra-uterine placental transfusion

Evaluation of Software-Optimized Protocols for Acoustic Noise Reduction During Brain MRI at 7 Tesla

Background: MR-generated acoustic noise may be particularly concerning at 7-Tesla (T) systems. Noise levels can be reduced by altering gradient output using software optimization. However, such alterations might influence image quality or prolong scan times, and these optimizations have not been well characterized. Purpose: To evaluate image quality, sound pressure levels (SPLs), and perceived noi

Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer’s Disease

Background: Alzheimer’s disease is a progressive, irreversible, and fatal disease for which accumulation of amyloid beta is thought to play a key role in pathogenesis. Aducanumab is a human monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta. Objectives: We evaluated the efficacy and safety of aducanumab in early Alzheimer’s disease. Design: EMERGE and ENGAG

Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations

Objective: The heterogeneity of systemic lupus erythematosus (SLE) constitutes clinical and therapeutical challenges. We therefore studied whether unrecognized disease subgroups can be identified by using autoantibody profiling together with HLA-DRB1 alleles and immunological and clinical data. Methods: An unsupervised cluster analysis was performed based on detection of 13 SLE-associated autoanti

Sex differences in efficacy of pharmacological therapies in heart failure with reduced ejection fraction : a meta-analysis

Aims: Recent studies have suggested potential sex differences in treatment response to pharmacological therapies in heart failure (HF). We performed a systematic review and meta-analysis of studies comparing treatment effects between men and women with HF and reduced ejection fraction (HFrEF) using established guideline-directed medical therapy and other emerging pharmacological treatments. Method

Subjective cognitive decline and anxious/depressive symptoms during the COVID-19 pandemic : what is the role of stress perception, stress resilience, and β-amyloid?

Background: The COVID-19 pandemic may worsen the mental health of people reporting subjective cognitive decline (SCD) and therefore their clinical prognosis. We aimed to investigate the association between the intensity of SCD and anxious/depressive symptoms during confinement and the underlying mechanisms. Methods: Two hundred fifty cognitively unimpaired participants completed the Hospital Anxie

Organizational and patient-level predictors for attaining key risk factor targets in cardiac rehabilitation after myocardial infarction : The Perfect-CR study

Background: Benefits of cardiac rehabilitation (CR) programme components on attaining risk factor targets post-myocardial infarction (MI) and their predictive strength relative to patient characteristics remain unclear. We aimed to identify organizational and patient-level predictors of risk factor target attainment at one-year post-MI. Methods: In this observational study data on CR organization

Rural-urban disparities in nutritional status among women in Ethiopia based on HIV serostatus : a cross-sectional study using demographic and health survey data

Background: Ethiopia is one of the sub-Saharan African countries most affected by the human immunodeficiency virus (HIV) epidemic and also by severe undernutrition, which is particularly prevalent among women. HIV infection, reproductive biology, and their role in society increase the vulnerability of women to malnutrition. Various factors including urbanization could cause differences in the nutr

Impact of mining projects on water and sanitation infrastructures and associated child health outcomes : a multi-country analysis of Demographic and Health Surveys (DHS) in sub-Saharan Africa

Background: Access to improved water and sanitation infrastructures are key determinants of health. The sub-Saharan African region in particular is lagging behind the ambitious goal of the 2030 Agenda for Sustainable Development to ensure universal access to improved and reliable water and sanitation for all (Sustainable Development Goal (SDG) 6). Large mining projects can promote economic growth

Calculation of the effective external dose rate to a person staying in the resettlement zone of the Vetka district of the Gomel region of Belarus based on in situ and ex situ assessments in 2016–2018

The aim of this study was to perform a preliminary assessment of the expected effective dose rate from external exposure to an adult individual staying at that part of the radioactively contaminated territory of the Vetka district of the Gomel region of the Republic of Belarus, from where residents had been resettled after the Chernobyl accident. For this assessment, in summer 2016 and 2018 soil s

Birthweight is associated with clinical characteristics in people with recently diagnosed type 2 diabetes

Aims/hypothesis: Low birthweight is a risk factor for type 2 diabetes but it is unknown whether low birthweight is associated with distinct clinical characteristics at disease onset. We examined whether a lower or higher birthweight in type 2 diabetes is associated with clinically relevant characteristics at disease onset. Methods: Midwife records were traced for 6866 individuals with type 2 diabe

Tau pathology as determinant of changes in atrophy and cerebral blood flow : a multi-modal longitudinal imaging study

Purpose: Tau pathology is associated with concurrent atrophy and decreased cerebral blood flow (CBF) in Alzheimer’s disease (AD), but less is known about their temporal relationships. Our aim was therefore to investigate the association of concurrent and longitudinal tau PET with longitudinal changes in atrophy and relative CBF. Methods: We included 61 individuals from the Amsterdam Dementia Cohor

Dose escalation to high-risk sub-volumes based on non-invasive imaging of hypoxia and glycolytic activity in canine solid tumors : A feasibility study

Introduction: Glycolytic activity and hypoxia are associated with poor prognosis and radiation resistance. Including both the tumor uptake of 2-deoxy-2-[18 F]-fluorodeoxyglucose (FDG) and the proposed hypoxia tracer copper(II)diacetyl-bis(N4)-methylsemithio-carbazone (Cu-ATSM) in targeted therapy planning may therefore lead to improved tumor control. In this study we analyzed the overlap between s

NextGen Sequencing (NGS) inftrastructure Report 2021

Microsoft Word - NGS_inftrastructure report 2021.docx Multipark infrastructure report form 2021 [Infrastructure name]: NextGen Sequencing (NGS) [Name of infrastructure manager/contact person]: Johan Jakobsson 1. Short description of the infrastructure. The MultiPark next generation sequencing (NGS) facility is located at the BMC in Lund. The core offers state-of-the art next generation sequencing

https://www.multipark.lu.se/sites/multipark.lu.se/files/2021-06/NextGen%20Sequencing%20(NGS)_inftrastructure%20report%202021.pdf - 2025-12-02

Fariborz Zelli Teaching Portfolio 2021

Zelli - Teaching Portfolio_2021-09-15 1 Teaching Portfolio Fariborz Zelli, Department of Political Science 1. Introduction The purpose of this document is to present my philosophy, development and diversification as a teacher in over 3,200 clock hours of teaching and training over the last twenty years. I will begin this presentation with a short overview of my teaching biography with its various

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2023-05/Fariborz%20Zelli_Teaching%20Portfolio_2021.pdf - 2025-12-02

Educational Unit

Educational Unit | Student website LTH Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifia

https://www.student.lth.se/contact/educational-unit/ - 2025-12-01

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srYK e,*/o* LUNDS PROTOKOLL S ammanträd e 2020 -0 4 -28 Via zoom Kl. 15:00-17:15 UNIVERSITET lnstitutionen för utbildningsvetenskap Programråd för ämneslärarutbildning Närvarande ledamöter: Sinikka Neuhaus Fabian Beijer Ingrid Bosseldal Linnea Brink t.o.m. $ 10 Malin Dahlgren fr.o.m. $ 5 Urban Eriksson fr.o.m. $ 5 t.o.m. 1/2 $ l0 Charlotta Nilsson Jonas Granfeldtt.o.m. $ l0 David Gudmundsson Ander

https://www.uvet.lu.se/fileadmin/user_upload/uvet/lararutbildning/pdf/Protokoll/Protokoll_2020-04-28.pdf - 2025-12-01

Litteraturlista Industriell Miljöekonomi För Miljövetare

Litteraturlista Industriell miljöekonomi för miljövetare, MVEC20 Kurslitteratur Industriellt miljöarbete Brorson & Almgren, ISO 14001 för små och medelstora företag, 2019, beställs från SIS förlag – notera att den används primärt under de två första veckorna av kursen! Molthan-Hill, The business students guide to sustainable management, 2017. Delar av. Finns sökbar via LUBsearch. Johansson et al,

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2020-12/Litteraturlista%20Industriell%20milj%C3%B6ekonomi%20f%C3%B6r%20milj%C3%B6vetare.pdf - 2025-12-01