Filtyp
The dynamic properties of the glomerular filtration barrier (GFB) are of fundamental importance for the understanding of the physiology and pathophysiology of microalbuminuria and proteinuric diseases. In the studies of this doctoral thesis the properties of the rat glomerular filtration barrier were investigated under resting conditions and following a number of challenges using highly sensitive
Sediment sequences spanning the last 800 years from two small lakes in the south Swedish uplands were explored for assessment of effects of changing human population, local land-use practices and airborne pollution on lake-ecosystem functioning and resilience. Variations in nutrient cycling and deposition of lithogenic elements were studied, using a multi-proxy stratigraphic approach. Carbon and n
Over the last two decades there has been a striking and continuous increase in the prevalence of obesity both in industrialized and developing countries. Despite this global consistency there is a variation within countries with a higher prevalence of obesity within rural areas. The overall aim was to explore the prevalence of obesity and factors that influence the development of obesity in a rura
Recent technological advancements now allow us to obtain geographical position data for a wide range of animal movements. Here we used light-level geolocators to study the annual migration cycle in great reed warblers (Acrocephalus arundinaceus), a passerine bird breeding in Eurasia and wintering in sub-Saharan Africa. We were specifically interested in seasonal strategies in routes and schedules
The Swedish Antarctic Research Expedition named “SWEDARP” was performed during October 1988 through April 1989. The aim of our project was to study the radioactivity in air and water from Gothenburg to the Antarctic. Between Gothenburg and the Equator, the average activity concentration of 7Be in air was 4.3 ± 0.7 mBq/m3. The activity concentration of 7Be in the South Atlantic down to Antarctica v
This paper is concerned with the changing role of regional innovation systems and regional policies in supporting the transition of indigenous firms in developing countries from competing on low costs towards becoming knowledge providers in global value chains. Special attention is paid to policies supporting the emergence and development of the regional innovation system in this transition proces
Kuannersuit Glacier, a valley glacier on Disko Island in west Greenland, experienced a major surge from 1995 to 1998 where the glacier advanced 10.5 km and produced a similar to 65 m thick stacked sequence of debris-rich basal ice and meteoric glacier ice. The aim of this study is to describe the tectonic evolution of large englacial thrusts and the processes of basal ice formation using a multipr
Weathering of silicate minerals releases dissolved silicate (DSi) to the soil-vegetation system. Accumulation and recycling of this DSi by terrestrial ecosystems creates a pool of reactive Si on the continents that buffers DSi export to the ocean. Human perturbations to the functioning of the buffer have been a recent research focus, yet a common assumption is that the continental Si cycle is at s
We analysed Mg/Ca, Sr/Ca and Ca isotope ratios of benthonic foraminifers from sediment core tops retrieved during several research cruises in the Atlantic Ocean, in order to improve the understanding of isotope fractionation and element partitioning resulting from biomineralisation processes and changes in ambient conditions. Species include foraminifers secreting tests composed of hyaline low mag
Popular Abstract in Swedish Det finns ett starkt samband mellan en förenings struktur och dess egenskaper. En detaljerad tredimensionell bild av en förenings struktur på molekylnivå är därför grundläggande information för att förstå dess reaktivitet, stabilitet och fysikaliska egenskaper. Röntgenkristallografi är ett utmärkt redskap för att ta reda på ett ämnes struktur i en kristall. En kristallsThis thesis focuses on i) the effect of packing on the molecular geometry ii) packing arrangements of neutral Pd(II) and Pt(II) complexes iii) the trans influence in Pt(II) complexes iv) the differences in bonding in corresponding Pd(II) and Pt(II) complexes and v) the geometry of Pd(II) complexes with potential catalytic properties. Detailed three-dimensional structural information at the atomic
Popular Abstract in Swedish Organisationssammanslagningar är vanligt förekommande inom såväl offentlig som privat verksamhet. Effekterna för de anställda och för organisationerna är beroende av hur integrationsprocessen förlöper. En korsbefruktning kan äga rum när idéer och arbetssätt möts efter sammanslagningen. Syftet med avhandlingen är att analysera integrationsprocessen och undersöka om den kMergers of organizations are a widespread phenomenon in the public as well as in the private sector. The individual and the organizational outcomes are dependent on the success of the integration process. During the integration after a merger, a cross-fertilization of ideas, working methods etc. is possible and could pave the way for creative processes. The aim of the present thesis is to analyze
Background: Orthostatic hypercoagulability is proposed as a mechanism promoting cardiovascular and thromboembolic events after awakening and during prolonged orthostasis. We evaluated early changes in coagulation biomarkers induced by tilt testing among patients investigated for suspected syncope, aiming to test the hypothesis that orthostatic challenge evokes procoagulatory changes to a different
Den yttersta barriären mellan luften och blodomloppet i våra lungor består av en lipid-protein film. Denna lipid-protein blandning kallas för lungsurfaktant. Filmen bestående av lungsurfaktant stabiliserar alveolerna i våra lungor och gör att vi kan andas utan motstånd. Brist av lungsurfaktant kan orsaka svåra sjukdomar, till exempel hos förtidigt födda barn som ännu inte hunnit bilda tillräckligtThis thesis explores lipid self-assembly and aims to give a broad picture of self-assembly structures in simple and complex lipid-protein systems. The systems studied are lung surfactant, stratum corneum and simple model membranes. The lung surfactant mixture lines the alveolus in our lungs and stabilises the air- tissue interface. The lung surfactant lipid phase behaviour was here investigated wi
The boreal biome exchanges large amounts of carbon (C) and greenhouse gases (GHGs) with the atmosphere and thus significantly affects the global climate. A managed boreal landscape consists of various sinks and sources of carbon dioxide (CO2), methane (CH4), and dissolved organic and inorganic carbon (DOC and DIC) across forests, mires, lakes, and streams. Due to the spatial heterogeneity, large u
Peatlands and forests cover large areas of the boreal biome and are critical for global climate regulation. They also regulate regional climate through heat and water vapour exchange with the atmosphere. Understanding how land-atmosphere interactions in peatlands differ from forests may therefore be crucial for modelling boreal climate system dynamics and for assessing climate benefits of peatland
The principles of mutual trust and mutual recognition are well established features of EU law. On a technical level, it is clear that the principles may require adoption of foreign levels of protection in individual cases as well as in legislation. At a closer look, however, the principles through “the rule of reason” also may imply quite the opposite: the imposing of domestic requirements on fore
BACKGROUND: Genome-wide association studies (GWAS) identified variants at 19p13.1 and ZNF365 (10q21.2) as risk factors for breast cancer among BRCA1 and BRCA2 mutation carriers, respectively. We explored associations with ovarian cancer and with breast cancer by tumor histopathology for these variants in mutation carriers from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). METHO
Popular Abstract in Swedish Populära tidskrifter och flertalet debattörer har alltsedan 80-talet hävdat att privatisering leder automatiskt till en förbättring av företagets effektivitet. På grund av dessa diskussioner har man litat mycket på marknadskrafter, då man trott att dessa krafter kan ombilda organisationer med goda effekter. Avhandlingen är en kritik mot dessa ansatser. Författaren försöThe majority of research on privatisation has been driven by, inter alia, economics. Some economists have argued that private ownership introduces capital market pressures into inefficient state bureaucracies. Private property rights are expected to maximise the incentives for management to achieve a high level of production efficiency. The argument put forward in this research is that in so far a
In 2005 and 2010 the Amazon basin experienced two strong droughts', driven by shifts in the tropical hydrological regime(2) possibly associated with global climate change(3), as predicted by some global models'. Tree mortality increased after the 2005 drought(4), and regional atmospheric inversion modelling showed basin-wide decreases in CO2 uptake in 2010 compared with 2011 (ref. 5). But the resp
