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Precipitation over the Tibetan Plateau (TP) has major societal impacts in South and East Asia, but its spatiotemporal variations are not well understood, mainly because of the sparsely distributed in situ observation sites. With the help of the Global Precipitation Measurement satellite product IMERG and the ERA5 dataset, distinct precipitation seasonality features over the TP were objectively cla

Background. The symptoms of obsessive-compulsive disorder (OCD) are highly heterogeneous and it is unclear what is the optimal way to conceptualize this heterogeneity. This study aimed to establish a comprehensive symptom structure model of OCD across the lifespan using factor and network analytic techniques.Methods. A large multinational cohort of well-characterized children, adolescents, and adu

Thanks to Bruno Galantucci, “experimental semiotics” is usually nowadays taken to mean the study of “novel forms of communication which people develop when they cannot use pre-established communication systems”. In spite of Galantucci’s claim to have picked the label because it was free, it has actually been used in different ways at least twice before: by Colin Ware, who takes it to be involved w

BackgroundChildren and youth who experience divorce are found to have increased risk of emotional and behavioural adjustment problems. Different prevention programmes have been developed to help and support children. Previous studies have focused on the child or the group leader's experience with divorce groups, but studies describing parent's experience are missing. The aim of this study was to e

A fair distribution of accessibility to key activities is a central concern for distributive justice in transport planning. This implies that disparities in accessibility and the negative effects associated with a lack of accessibility should be mitigated. However, even though accessibility is not purely spatial or static, it is conventionally treated as if it were. Several studies have significan

The trend of using protein produced from microorganisms to be a meat substitute or replacing other meat alternative sources such as soy and pea is becoming increasingly popular because of its possibility to produce meat-like food products and other functional properties such as its emulsifying properties. The effective use of mycoprotein for food applications requires liberation of cell protein by

This paper aims to show how systems thinking can be used to investigate barriers to organisational change management. The case study described in this paper would be useful to managers who want to implement change in their own organisations. Soft Systems Methodology and ETHICS were used due to their flexible, responsive, and emergent nature. Also, soft systems methodology (SSM) and ETHICS (Effecti

Marine gastropods are characterized by an incredible variation in shell color. In this review, we aim to introduce researchers to previous studies of shell color polymorphism in this group of animals, trying to provide an overview of the topic and highlighting some potential avenues for future research. For this, we tackle the different aspects of shell color polymorphism in marine gastropods: its

Triosephosphate isomerase (TIM) is a proficient catalyst of the reversible isomerization of dihydroxyacetone phosphate (DHAP) to d-glyceraldehyde phosphate (GAP), via general base catalysis by E165. Historically, this enzyme has been an extremely important model system for understanding the fundamentals of biological catalysis. TIM is activated through an energetically demanding conformational cha

This article presents preliminary findings from a design ethnographic study examining pelvic floor care practices from the perspective of patients with pelvic floor injuries caused by birth treated at the continence clinic in Sundsvall's Hospital, Sweden. The aim is to enhance our understanding of women's experiences of pelvic floor injury, provide insights into living with pelvic floor injury, an

A double twin isothermal microcalorimeter has been designed and its performance has been tested experimentally. The calorimeter makes it possible to continuously and isothermally scan a solid sample in a broad range of relative vapor pressures at near-equilibrium conditions. The method is suited for measurements with water vapor as well as organic vapors and has been tested at temperatures between

This conceptual chapter investigates how knowledge moves across different “social fields” (Bourdieu, 2005b). We propose a certain social Gestalt new knowledge discussion creates the dialogically constructed antenarrative field. An antenarrative field is a social space for knowledge exchange where agents speculate on future scenarios’ potential for realization, and our notion of the antenarrative f

Characterization of gene expression in pancreatic islets and its alteration in type 2 diabetes (T2D) are vital in understanding islet function and T2D pathogenesis. We leveraged RNA sequencing and genome-wide genotyping in islets from 188 donors to create the Islet Gene View (IGW) platform to make this information easily accessible to the scientific community. Expression data were related to islet

Sharing the findings of research projects to improve future practice is often an important objective of educational research. However disseminating the results to groups that will directly benefit can sometimes be problematic and there may also be complexities around presenting research in a context that gives real-world relevance. The informal environment of game play is one method that can be ut

Circular business models (CBMs) promise improved resource efficiency, value creation and retention. Still, CBM operationalization among large incumbents remains slow in practice. Yet, this plays a critical role in driving industry transformations towards sustainability. Prior research outlines challenges that incumbents encounter when operationalizing CBMs - yet remains fragmented and unable to ex

Introduction: The experiences of living with Parkinson's disease (PD) from the perspective of newly diagnosed persons with PD (PwPD) have not been previously described. Aim: This study aimed to gain a better understanding of the impact of living with the early stages of PD. Methods: A qualitative interview study was conducted among nine persons, seven men and two women, from southern Sweden. Parti

A prime function of the mucosal immune system is the production of secretory immunoglobulin (Ig) A antibodies. To initiate this, the organized lymphoid system is strategically located at sites where mucosal antigens are encountered. The follicle-associated epithelium (FAE) hosts specialized cells called M cells that effectively take up antigen. After transport of antigen via the FAE, the mucosal-a