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Verbenone—the universal bark beetle repellent? Its origin, effects, and ecological roles

Bark beetles (Curculionidae: Scolytinae) spend most of their life in tissues of host plants, with several species representing economically relevant pests. Their behaviour is largely guided by complex olfactory cues. The compound verbenone was discovered early in the history of bark beetle pheromone research and is now sometimes referred to as a ‘universal bark beetle repellent’. However, some stu

Normalization of puberty and adult height in girls with Turner syndrome : results of the Swedish Growth Hormone trials initiating transition into adulthood

Objective: To study the impact of GH dose and age at GH start in girls with Turner syndrome (TS), aiming for normal height and age at pubertal onset (PO) and at adult height (AH). However, age at diagnosis will limit treatment possibilities. Methods: National multicenter investigator-initiated studies (TNR 87-052-01 and TNR 88-072) in girls with TS, age 3–16 years at GH start during year 1987–1998

Abnormal cerebral hemodynamics and blood-brain barrier permeability detected with perfusion MRI in systemic lupus erythematosus patients

Objective: Dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) has previously shown alterations in cerebral perfusion in patients with systemic lupus erythematosus (SLE). However, the results have been inconsistent, in particular regarding neuropsychiatric (NP) SLE. Thus, we investigated perfusion-based measures in different brain regions in SLE patients with and without NP invo

Towards sustainable plastics : Microbial production of aromatic and aliphatic building blocks from biobased feedstock and plastic hydrolysate

The current plastic system is unsustainable and needs to change. Plastics are mainly produced from fossil feedstock, contributing to greenhouse gas emissions, and low rate of post-consumer recycling results in pollution on land and in oceans with high ecological impact, and huge loss of valuable material. There is an urgent need to find solutions for shifting the raw material base to renewable res

Use of flutemetamol F18-labeled positron emission tomography and other biomarkers to assess risk of clinical progression in patients with amnestic mild cognitive impairment

Importance: Patients with amnestic mild cognitive impairment (aMCI) may progress to clinical Alzheimer disease (AD), remain stable, or revert to normal. Earlier progression to AD among patients who were β-amyloid positive vs those who were β-amyloid negative has been previously observed. Current research now accepts that a combination of biomarkers could provide greater refinement in the assessmen

A comparative analysis of the dynamics of Plasmodium relictum (GRW4) development in the blood during single and co-infections

Although co-infections and interactions of parasites are a very common phenomenon in the wild, information received from studies on avian Plasmodium spp. is scarce and fragmented due to its complex nature. Different interactions of parasites and domination of one parasite may have a detrimental effect on transmission success of another pathogen. Untangling these interactions and competitive behavi

Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial

Background: Patent foramen ovale (PFO) is a contributor to embolic stroke of undetermined source (ESUS). Subgroup analyses from previous studies suggest that anticoagulation could reduce recurrent stroke compared with antiplatelet therapy. We hypothesised that anticoagulant treatment with rivaroxaban, an oral factor Xa inhibitor, would reduce the risk of recurrent ischaemic stroke compared with as

Medical teamwork and the evolution of safety science : A critical review

There is widespread consensus that teamwork constitutes one of the key requirements in today’s multidisciplinary and highly complex system of delivering care. In recent years, increasing attention has been given to questions of how to define, teach, measure, and improve teamwork in healthcare. However, one cannot help but feel a certain disconnect between this ongoing trend in healthcare with an a

Child and Adolescent Health From 1990 to 2015 : Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study

Importance: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health.Objective: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion.Evidence Review: Cause-specific mortality an

Social Jetlag and Its Association With Screen Time and Nighttime Texting Among Adolescents in Sweden : A Cross-Sectional Study

The discrepancy between social and biological clock due to sleep and wake up time difference across weekdays and weekends is referred as social jetlag. The overall aim of this study is to test whether there is an association between both screen time and nighttime texting and social jetlag among 13- to 15-year-old adolescents in Sweden. This study included a cross-sectional survey in which data wer

Some Physical and Environmental Aspects of Shallow Ice Covered Lakes : Emphasis on Lake Vendyurskoe, Karelia, Russia.

The ice cover presence on the surface of a lake insulates the water body from the atmosphere. This prevents or reduces the influence of processes which depend on the exchange between the atmosphere and the water surface. This implies significant reduction or elimination of some processes taking place at the open water surface; for instance, a substantial reduction in solar energy penetrating to th

Environmental modifiers of the relationship between water table depth and Ellenberg's indicator of soil moisture

Ellenberg indicator values for plant species are widely used metrics in ecology, providing a proxy measure of environmental conditions, without direct measurements. They integrate environmental conditions over time since species will only persist where conditions are favourable. Ellenberg moisture (F) values summarise the hydrological environment experienced by plants. However, the relationship be

Towards sustainable water use in industry: a case study of the oil refinery industry in Kazakhstan

The concept of “Sustainable water use” (SWU) aims to assure three pillars of sustainability related to the water sector: the social, environmental, and economical. Industrial development, especially in developing countries, requires an adequate response, as industrial activities are recognized as one of the major sources of water pollution, what leads to deterioration of environmental safety and w

Neoadjuvant Trastuzumab, Pertuzumab, and Docetaxel vs Trastuzumab Emtansine in Patients with ERBB2-Positive Breast Cancer : A Phase 2 Randomized Clinical Trial

Importance: Trastuzumab emtansine (T-DM1) is presently approved for treatment of advanced breast cancer and after incomplete response to neoadjuvant therapy, but the potential of T-DM1 as monotherapy is so far unknown. Objective: To assess pathologic complete response (pCR) to standard neoadjuvant therapy of combination docetaxel, trastuzumab, and pertuzumab (DTP) vs T-DM1 monotherapy in patients

Structural and Functional Analyses of Xyloside-primed Glycosaminoglycans

Glycosaminoglycans (GAGs) are polysaccharides produced by essentially all mammalian cells. Due to their enormous structural diversity, they are involved in many biological processes both in health and disease, including all stages of tumor progression. GAGs are normally attached to a core protein as a part of a proteoglycan; however, GAG biosynthesis can be induced by compounds composed of a xylos

Evaluation of physical work capacity and leg muscle fatigue during exhaustive stair ascending evacuation

AbstractPhysical exhaustion can constrain human ascending work capacity and performance during emergency evacuation on stairs. The overall aim of this research was to explore and compare stair ascending capacities and physiological limitations during two different strategies: self-preferred pace in three different public stairways in the field, and controlled pace in a laboratory on a stair machin

Don’t Mess with My Milk! The Mystery of Spectacular Mundane Consumption

This study aims to deepen the understanding of mundane consumption by examining hidden meanings in the case of the Milk Uprising, when sharp decreases in the availability of Skånemejerier’s milk in Scania, Sweden, in 2009 ignited a major consumer revolt. We argue that existing literature is inadequate to explain this case where mundane consumption all of a sudden became spectacular, and that such

Omplacerad eller utsorterad? - En studie om den rättsliga utvecklingen kring reglerna om omplacering i 7 § andra stycket LAS och omplacering i turordning enligt 22 § fjärde stycket LAS

Lagen om anställningsskydd infördes år 1974 för att trygga anställningen för alla enskilda arbetstagare på den svenska arbetsmarknaden. Tidigare hade arbetstagarnas rättigheter reglerats i kollektivavtal och endast vissa arbetstagares rättigheter var reglerade i lag. Några regler som infördes i 1974 års lag var bland annat saklig grund för uppsägning enigt 7 § LAS. För att saklig grund skulle anseThe Employment Protection Act from 1974 was implemented in to Swedish law as a way to secure the employments of the employees. Before the implementation of the Act, the rights of the employees were regulated in collective agreements. By then there were only some rights regulated in the law. Some of the regulations that were implemented in to the Employment Protection Act was the 7§. The 7 § states

The Dissipating Energy Flow method for analysing generator contribution to power system damping -- evaluation and interpretation

En ny metod påstås kunna analysera störningar i elnätet i realtid med hjälp av befintliga mätinstrument. Genom att beräkna flöden av svängningsenergi kan olika generatorers roller i störningen visualiseras. Från kontrollrum kan störningskällor kopplas bort och generatorers bidrag till dämpning kontinuerligt utvärderas. Men bakgrunden till metoden är grumlig och tolkningen av svängningsenergin är oElectromechanical oscillations is a power system phenomenon where generator rotors oscillate, leading to oscillatory power flows. Damping of such oscillations is important for system stability. Forced oscillations is a special case where one faulty component is the source of the oscillation. This report concerns the Dissipating Energy Flow (DEF), which is an energy-based method for analysing dampi