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A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity : results from a large European cohort

Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proport

Serum biomarkers of early stages of hypertrophic cardiomyopathy in a young population

Background: Hypertrophic cardiomyopathy (HCM) is the most common monogenic cardiac disorder and the leading cause of sudden cardiac death in the young. Although in a majority of HCM cases there are gene mutations coding for sarcomere proteins, the onset for the clinical consequences of these mutations are difficult to predict, as these mutations do not show any clear relationship to the degree of

Systematic evaluation of observational methods assessing biomechanical exposures at work

Objectives This systematic review aimed to identify published observational methods assessing biomechanical exposures in occupational settings and evaluate them with reference to the needs of different users. Methods We searched scientific databases and the internet for material from 1965 to September 2008. Methods were included if they were primarily based on the systematic observation of work, t

ST-recovery loop of exercise-induced ST deviation in the identification of coronary artery disease: Which parameters should we measure?

This study aimed to characterize the ST-recovery loop and assess which range of heart rates (HRs) best discriminates between patients with and without significant coronary artery stenosis. Bicycle exercise tests were undertaken in 44 men and IS women with coronary artery disease (CAD) and in 59 controls (26 men, 33 women) in the same age range with no signs of CAD. The ST level and the ST-segment

Probing the nature of the G1 clump stellar overdensity in the outskirts of M31

We present deep Hubble Space Telescope ACS observations of the G1 clump, a distinct stellar overdensity lying at similar to 30 kpc along the southwestern major axis of M31, close to the G1 globular cluster ( from the work of Ferguson and coworkers). Our well-populated color-magnitude diagram reaches similar to 7 mag below the red giant branch tip with 90% completeness, and allows the detection of

EULAR evidence based recommendations for the management of hand osteoarthritis: report of a task force of the EULAR standing committee for international clinical studies including therapeutics (ESCISIT)

Objectives: To develop evidence based recommendations for the management of hand osteoarthritis (OA). Methods: The multidisciplinary guideline development group comprised 16 rheumatologists, one physiatrist, one orthopaedic surgeon, two allied health professionals, and one evidence based medicine expert, representing 15 different European countries. Each participant contributed up to 10 propositio

MR Spectroscopy Using Normalized and Non-normalized Metabolite Ratios for Differentiating Recurrent Brain Tumor from Radiation Injury

Rationale and Objectives: To compare the ability of normalized versus non-normalized metabolite ratios to differentiate recurrent brain tumor from radiation injury using magnetic resonance spectroscopy (MRS) in previously treated patients. Materials and Methods: Twenty-five patients with previous diagnosis of primary intracranial neoplasm confirmed with biopsy/resection, previously treated with ra

Stability and performance of supported Fe-V-oxide catalysts in methanol oxidation

As the commercial Fe-Mo-oxide catalyst for methanol oxidation to formaldehyde suffers from deactivation by Mo volatilization, alternative catalysts are of interest. Therefore, TiO2-, alpha-Al2O3- and SiO2-supported (Fe)-V-O catalysts were prepared with loading up to 30 μmol of each metal per msq. surface area of the support. The samples were activity tested using a high inlet concentration of meth

Abdominal tenderness in ascites patients indicates spontaneous bacterial peritonitis

Background: Spontaneous bacterial peritonitis (SBP), which has been reported to be present in 10-30% of patients with cirrhotic ascites, may easily be overlooked. An important aim of our study was to determine whether there are any clinical signs which, in clinical practice, may predict or exclude SBP. Methods: We studied 133 patients with cirrhotic ascites from medical units at nine Swedish unive

Riboflavin and Ultraviolet A Collagen Crosslinking of the Cornea for the Treatment of Keratitis.

PURPOSE:: To describe riboflavin and ultraviolet light (UV) collagen crosslinking as an effective treatment for infectious keratitis. METHODS:: A 25-year-old previously healthy female contact lens user was diagnosed with unilateral severe keratitis with unclear pathogenesis, although the clinical presentation suggested acanthamoeba as the infectious agent. A 4-mm diameter, annular, semi-opaque inf

Development of a purification process for Protease X and implementation of an immobilized enzyme reactor

Biomolekyler, så som proteiner, produceras genom att DNA som kodar för dessa molekyler tillsätts i celler. Cellerna kan exempelvis vara bakterier, jäst eller från däggdjur. Dessa celler producerar inte enbart de önskade proteinerna utan även andra proteiner som är nödvändiga för att cellerna ska kunna överleva. Som en följd av detta är upprening en av de viktigaste processerna i produktionen av prDownstream processing is an essential part in the production of biomolecules and the optimization of these processes are of great value, since they can be both time consuming and expensive. One common type of enzyme used in different biotechnical approaches is proteases and in this study Protease X was investigated. In order to use the enzyme in a process, a purification procedure needs to be esta

Thin Capitalization in the OECD, the EU and Sweden: policy responses, evaluation and alternatives.

The issue of thin capitalization has risen in importance in recent years, to the point that it warranted international action. That action came in the form of Action 4 of the OECD BEPS Project, of Article 4 of the EU ATAD and of the new interest deduction limitation rules in the national Swedish legislation. The main part of the chosen rule in all these instances disallows interest deduction over

Learnings for Future

In the present time, the rate of environmental degradation requires us to use all available means to avoid further damage and restore the environment to the best of our possibilities. Education is an important channel to promote environmentalism and sustainability, and to promote pro-environmental individual decisions, especially regarding consumption and purchasing patterns. The case study analys

A Method for Evaluating and Mapping Terrestrial Deposition and Preservation Potential- for Palaeostorm Surge Traces. Remote Mapping of the Coast of Scania, Blekinge and Halland, in Southern Sweden, with a Field Study at Dalköpinge Ängar, Trelleborg

Studier av palaeostormfloder ger bakgrund till inom vilka intevall stormar av olika storlek förväntas återkomma och träffa olika områden. Denna information kan användas vid modellering, riskbedömning och stadsplanering. Genom att använda de marina ekvationerna av Nittrouer och Sternberg (1981; The formation of sedimentary strata in an allochthonous shelf environment: the Washington continental sheStudies of palaeostorm surges provides background into at what frequencies storms of different magnitudes are expected to return and hit different areas. This information can be used when modelling, doing risk assesments and city planing. Using the marine equations of Nittrouer and Sternberg (1981; The formation of sedimentary strata in an allochthonous shelf environment: the Washington continenta

A Russian record of a Middle Ordovician shower : extraterrestrial chromite in Volkhovian-Kundan (lower Darriwilian) strata at Lynna River, St. Petersburg Region

Tidigare studier har dokumenterat ett flertal fossila meteoriter samt höga koncentrationer av utomjordisk kromit (ett järn-kromoxidmineral) i cirka 467 miljoner år gamla, mellanordoviciska sedimentlager. Fynden antas vara resultaten av ett tillfälligt förhöjt inflöde av meteoritiskt material, efter uppbrytningen av en kropp i asteroidbältet – de så kallade L-kondriternas föräldrakropp – för omkriNumerous fossil meteorites and high concentrations of sediment-dispersed extraterrestrial chromite (EC) grains with typical ordinary chondritic composition have previously been documented from 467±1.6 Ma Ma lower Kundan (Middle Ordovician) strata. These finds most likely reflect a temporarily enhanced influx of ordinary chon- dritic matter, following the disruption of the L chondrite parent body i

Osteoarthritis of the Knee: Review of Risk Factors and Treatment Programs with Special Reference to Evidence-Based Research

Osteoarthritis is a widespread disease leading to physical disability affecting quality of life. It is primarily regarded as a cartilage disease but affect all tissues of a joint. Osteoarthritis can be regarded as an organ failure. Knee osteoarthritis is common in Kuwait, especially in women. The main symptoms are pain, stiffness and weakness affecting knee function. The diagnosis is made by histo

Att ligga i Lund - En undersökning om hur universitetsstudenter talar om sexualitet

“To lay in Lund” – A study about the way university students speak about sexuality Recently allegations concerning the sexual habits of young people have attracted attention in Swedish research. Assumptions regarding an increased number in sexual partners and a change in attitude towards sexuality are two of the noted aspects. The aim of this study was to develop an understanding of the way studen

Low-dose computed tomography of the lumbar spine: a phantom study on imaging parameters and image quality

Background: Lumbar spine radiography has limited diagnostic value but low radiation dose compared with computed tomography (CT). The average effective radiation dose from lumbar spine radiography is about 1.1 mSv. Low-dose lumbar spine CT may be an alternative to increase the diagnostic value at low radiation dose, around 1 mSv. Purpose: To determine the optimal settings for low-dose lumbar spine

Gene duplication and fragmentation in the zebra finch major histocompatibility complex

Background: Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects. Avian MHC organization is of particular interest because the chicken Gallus gallus, the avian species with the best characterized MHC, possesses a highly streamlined minimal essential MHC, which is linked to resis

Översvämning av kyrkomiljöer - hur en ökad förekomst av översvämningar kan påverka kyrkomiljöer i Lunds stift

När syndafloden kommer När havsnivån stiger och nederbörden ökar riskerar upp till 29 utav Lunds stifts ca 500 kyrkobyggnader att drabbas av översvämningar. Detta betyder att behovet av skydd mot översvämningar troligtvis kommer öka för dessa miljöer i framtiden. Förekomsten av översvämningar förväntas öka till följd av klimatförändringen. Utav de ca 500 kyrkobyggnaderna i Lunds stift kan upp tThe occurrence of floods is expected to increase due to climate change, which may lead to destruction or loss of value of cultural heritage sites. There are approximately 500 church buildings in Lund diocese. The aim of this study was to investigate how this might affect the church buildings, their inventory, and cemeteries within Lund diocese, which are protected under Swedish law. The aim was al