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Interfacing HPLC with MALDI- and ESI-MS for Automated High Sensitivity Analysis of Proteins and Peptides

The research described in this thesis has an interdisciplinary approach dealing with chemical, biological, and technical issues. One objective was to interface miniaturized liquid chromatography (LC) to mass spectrometry, i.e. MALDI-TOF MS and ESI-MS, in an unattended mode for high sensitivity determination of proteins and peptides. The coupling between capillary LC and MALDI was accomplished by e

The crystal structure of peroxymyoglobin generated through cryoradiolytic reduction of myoglobin compound III during data collection

Myoglobin has the ability to react with hydrogen peroxide, generating high-valent complexes similar to peroxidases (compounds I and II), and in the presence of excess hydrogen peroxide a third intermediate, compound III, with an oxymyoglobin-type structure is generated from compound II. The compound III is, however, easily one-electron reduced to peroxymyoglobin by synchrotron radiation during cry

F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis

This systematic review was designed to provide more precise effect estimates of inhibitor development for the various types of F8 gene mutations in patients with severe hemophilia A. The primary outcome was inhibitor development and the secondary outcome was high-titer-inhibitor development. Asystematic literature search was performed to include cohort studies published in peer-reviewed journals w

Test of an empirical method for ozone detection in the stratosphere using two filtered broadband UV-meters

We describe a simple method to detect significant changes of the total ozone column from global (diffuse and direct) zenith sky measurements taken at the Earth’s surface. The calculation of the total ozone column relies on measured irradiance at two wavelengths in the ultra violet part of the solar spectrum. One of these (i.e. 306 nm) are appreciable absorbed by ozone whereas the other (i.e. 360 n

Reduction Potentials and Acidity Constants of Mn Superoxide Dismutase Calculated by QM/MM Free-Energy Methods.

We used two theoretical methods to estimate reduction potentials and acidity constants in Mn superoxide dismutase (MnSOD), namely combined quantum mechanical and molecular mechanics (QM/MM) thermodynamic cycle perturbation (QTCP) and the QM/MM-PBSA approach. In the latter, QM/MM energies are combined with continuum solvation energies calculated by solving the Poisson-Boltzmann equation (PB) or by

Systematic evaluation of observational methods assessing biomechanical exposures at work

Objectives This systematic review aimed to identify published observational methods assessing biomechanical exposures in occupational settings and evaluate them with reference to the needs of different users. Methods We searched scientific databases and the internet for material from 1965 to September 2008. Methods were included if they were primarily based on the systematic observation of work, t

Stability and performance of supported Fe-V-oxide catalysts in methanol oxidation

As the commercial Fe-Mo-oxide catalyst for methanol oxidation to formaldehyde suffers from deactivation by Mo volatilization, alternative catalysts are of interest. Therefore, TiO2-, alpha-Al2O3- and SiO2-supported (Fe)-V-O catalysts were prepared with loading up to 30 μmol of each metal per msq. surface area of the support. The samples were activity tested using a high inlet concentration of meth

Calculation of geomagnetically induced currents in the 400 kV power grid in southern Sweden

Sweden has experienced many geomagnetically induced current (GIC) events in the past, which is obviously due to the high-latitude location of the country. The largest GIC, almost 300 A, was measured in southern Sweden in the earthing lead of a 400 kV transformer neutral during the magnetic storm on 6 April 2000. On 30 October 2003, the city of Malmo at the southern coast suffered from a power blac

Unexpected early extinction of the European pond turtle (Emys orbicularis) in Sweden and climatic impact on its Holocene range

Using ancient DNA sequences of subfossil European pond turtles (Emys orbicularis) from Britain, Central and North Europe and accelerator mass spectrometry radiocarbon dating for turtle remains from most Swedish sites, we provide evidence for a Holocene range expansion of the pond turtle from the southeastern Balkans into Britain, Central Europe and Scandinavia, according to the 'grasshopper patter

Abdominal tenderness in ascites patients indicates spontaneous bacterial peritonitis

Background: Spontaneous bacterial peritonitis (SBP), which has been reported to be present in 10-30% of patients with cirrhotic ascites, may easily be overlooked. An important aim of our study was to determine whether there are any clinical signs which, in clinical practice, may predict or exclude SBP. Methods: We studied 133 patients with cirrhotic ascites from medical units at nine Swedish unive

ST-recovery loop of exercise-induced ST deviation in the identification of coronary artery disease: Which parameters should we measure?

This study aimed to characterize the ST-recovery loop and assess which range of heart rates (HRs) best discriminates between patients with and without significant coronary artery stenosis. Bicycle exercise tests were undertaken in 44 men and IS women with coronary artery disease (CAD) and in 59 controls (26 men, 33 women) in the same age range with no signs of CAD. The ST level and the ST-segment

Probing the nature of the G1 clump stellar overdensity in the outskirts of M31

We present deep Hubble Space Telescope ACS observations of the G1 clump, a distinct stellar overdensity lying at similar to 30 kpc along the southwestern major axis of M31, close to the G1 globular cluster ( from the work of Ferguson and coworkers). Our well-populated color-magnitude diagram reaches similar to 7 mag below the red giant branch tip with 90% completeness, and allows the detection of

Riboflavin and Ultraviolet A Collagen Crosslinking of the Cornea for the Treatment of Keratitis.

PURPOSE:: To describe riboflavin and ultraviolet light (UV) collagen crosslinking as an effective treatment for infectious keratitis. METHODS:: A 25-year-old previously healthy female contact lens user was diagnosed with unilateral severe keratitis with unclear pathogenesis, although the clinical presentation suggested acanthamoeba as the infectious agent. A 4-mm diameter, annular, semi-opaque inf

Thin Film Engineering of Indium Tin Oxide: Large area flat panel displays application

Indium Tin Oxide (ITO) thin films with a variety of microstructures were deposited using a large area conventional DC magnetron sputtering system for flat panel displays manufacturing. Highly uniform ITO films with an average thickness of ∼100 ± 3 nm on the ∼0.6 m2 substrate area were obtained. Film structures with small amounts of crystalline sites were produced by room temperature deposition, an

A Voyage to Vardø – A Scientific Account of an Unscientific Expedition

After the “Venus Transit Conference” that took place at the University of Tromsø from June 2 to June 3, 2012, participants were given the opportunity to either stay in Tromsø until the night of June 5–6, or to participate in a voyage to Finnmark, where the historical sites Vardø, Hammerfest, and the North Cape were to be visited. This voyage culminated in the observation of the 2012 transit of Ven

Allman studieplan humanekologi

Brevmall Postadress Sölvegatan 10, 223 62 LUND Besöksadress Geocentrum 1, Sölvegatan 10 Telefon växel 046-222 17 59 Fax 046-222 84 01 E-post expeditionen@keg.lu.se Webbadress www.keg.lu.se Ins t i tu t ionen fö r ku l turgeograf i och ekonomisk geograf i Avdeln ingen för humanekologi Allmän studieplan för utbildning på forskarnivå i humanekologi Studieplanen är fastställd av Samhällsvetenskapliga

https://www.keg.lu.se/sites/keg.lu.se/files/allman_studieplan_humanekologi.pdf - 2026-06-17

Validering Av Meriter 230119

Lägg till titel Socialhögskolan Sammanställning av kunnande i förhållande till valideringskriterierna Namn: Personnummer: Ange tydligt vilka av dina förvärvade meriter (formella, icke formella och informella) som du anser motsvarar respektive valideringskriterium. Ett kriterium kan motsvaras av en eller flera typer av meriter, och en merit kan uppfylla flera kriterier. Alla åberopade meriter ska s

https://www.soch.lu.se/sites/soch.lu.se/files/2023-01/Validering%20av%20meriter%20230119.pdf - 2026-06-17

Utbildningsplan kulturskolepedagog

Microsoft Word - Utbildningsplan för Kulturskolepedagog.docx Kulturskolepedagog, inriktning musik, konst eller teater Utbildningens namn: Kulturskolepedagog Antal Högskolepoäng: 90 Nivå: Grund Utbildningskodkod: LGKSP Helfart /Halvfart Fastställd: 2018-11-28 Utbildningsbeskrivning Kulturskolepedagogutbildningen ges vid Lunds universitet, Musikhögskolan i Malmö och syftar till att komplettera tidig

https://www.mhm.lu.se/sites/mhm.lu.se/files/utbildningsplan_kulturskolepedagog.pdf - 2026-06-17

Allmän-studieplan-genusvetenskap-20210311

Allmän studieplan för utbildning på forskarnivå i genusvetenskap Sida 1 av 11 Fakultetsstyrelsen ALLMÄN STUDIEPLAN FÖR GENUSVETENSKAP Diarienummer U 2021/139 2021-03-11 Allmän studieplan för utbildning på forskarnivå i genusvetenskap Allmän studieplan för utbildning på forskarnivå i genusvetenskap är fastställd av Samhällsvetenskapliga fakultetsstyrelsen 2021-03-11, dnr U 2021/139. Studier enligt

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2021-03/Allm%C3%A4n-studieplan-genusvetenskap-20210311.pdf - 2026-06-17

Impact of Multiple Injection Strategies on Efficiency and Combustion Characteristics in an Optical PPC Engine

Partially premixed combustion (PPC) is a promising way to achieve high thermal efficiency and low emissions, especially by using multiple injection strategies. The mechanisms behind PPC efficiency are still to be explained and explored. In this paper, multiple injections have been used to affect the gross indicated efficiency in an optical PPC engine modified from a Volvo MD13 heavy-duty diesel en