Sökresultat

Genomic rearrangements in cancer cells can create gene fusions where the juxtaposition of two different genes leads to the production of chimeric proteins or altered gene expression through promoter-swapping. We have previously shown that fusion transcripts involving microRNA (miRNA) host genes contribute to deregulation of miRNA expression regardless of the protein-coding potential of these trans

BACKGROUND: The ongoing climate change will elevate the incidence of diarrheal in 2030-2050 in Asia, including Taiwan. This study investigated associations between meteorological factors (temperature, precipitation) and burden of age-cause-specific diarrheal diseases in six regions of Taiwan using 13 years of (2004-2016) population-based data.METHODS: Weekly cause-specific diarrheal and meteorolog

Introduction The conventional ECG is commonly used to screen for hypertrophic cardiomyopathy (HCM), but up to 25% of adults and possibly larger percentages of children with HCM have no distinctive abnormalities on the conventional ECG, whereas 5 to 15% of healthy young athletes do. Recently, a 5-min resting advanced 12-lead ECG test ("A-ECG score") showed superiority to pooled criteria from the st

Managing the resources of a virtualized data-center is a key issue in cloud computing. Existing research mostly assumes that applications are either allocated the required resources or fail. Combined with the fact that most cloud applications have dynamic resource requirements, this imposes a fundamental limitation to cloud computing: To guarantee on-demand resource allocations, the data-center ne

The paper reports a project conducted within the framework of the National Library of Sweden's Expert Group on Library Statistics. The project is financed by the National Library of Sweden, and it aims to capture how library managements make use of the current library statistics (based on the ISO-standard) in the decision-making process. Questions are also asked about the quality and usefulness of

There are many market and organisational barriers to the breakthrough of a new industrial field such as bioenergy. For many observers, recent high prices of oil and the significant policy support measures throughout Europe, would appear to have created economic conditions that should be sufficient for the industry to prosper. However, a significant number of policies supposed to expand bioenergy (

The frame story
takes place in a dystopian Europe, possibly some kind of European Union around 2050 – in a state of conflicts and decay. The protagonists are a retired general, Piscator (cf. Fisher King) and a former journalist, Perle Vaus (cf. Perlesvaus/Perceval/Parsifal). She lost her home because of a new genderrelated law and stays homeless with others, covered by the Saxon bridge.

Purpose – This paper aims to extend insights about the relationship between inter-organizational collaboration and approaches to control from the perspective of decision-makers. We investigate the relationship between approaches to control and intended forms of integration between actors responsible for solving the complex problem of integrated person-centered care for elderly with diverse and sig

Carrying capacity, a concept entrenched in the natural resources and environmental field for nearly two centuries, has continually evolved to address the conflicts and sustainability of the human- nature relationship. This paper introduces an analytical framework for understanding carrying capacity within the context of the human- nature relationship. It systematically reviews the progression of i

Background: Cardiac arrhythmias are a common health problem. Both common and rare genetic risk factors exist for cardiac arrhythmias. Cardiac amyloidosis is a rare disease that may manifest various arrhythmias. Few large-scale whole exome sequencing studies elucidating the contribution of rare variations to arrhythmias have been published. Objective: To access gene collapsing analysis of rare vari