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Rationale & Objective: Use of cystatin C in addition to creatinine to estimate glomerular filtration rate (estimated glomerular filtration rate based on cystatin C [eGFRcys] and estimated glomerular filtration rate based on creatinine [eGFRcr], respectively) is increasing. When eGFRcr and eGFRcys are discordant, it is not known which is more accurate, leading to uncertainty in clinical decisio

The favorable pharmacokinetics of MMC, used during intraperitoneal chemotherapy, has been reported in several studies [11-19]. A major safety issue in studies using intraperitoneal chemotherapy perfusion is the resulting systemic drug exposure. The AUCplasma is determined by the dose, the clearance, and the fraction absorbed from the peritoneal cavity. The reported mean plasma peak concentrations

Extant literature points to how the risk of discrimination is intrinsic to AI systems owing to the dependence on training data and the difficulty of post hoc algorithmic auditing. Transparency and auditability limitations are problematic both for companies’ prevention efforts and for government oversight, both in terms of how artificial intelligence (AI) systems function and how large-scale digita

Purpose: The aim of this study was to examine test–retest reliability and responsiveness of the short version (6-item) Hip Return to Sport after Injury (Hip-RSI) scale in patients following hip arthroscopy. Methods: The study included 100 hip arthroscopy patients responding to a digital survey including the short version (6-item) Hip-RSI, International Hip Outcome Tool (short version) (iHOT-12) an

Do you ever hear a medical term (e.g., demoralization) and wonderwhy it wasn’ t discussed in medical school? Do you ever wonderwhether some words or concepts mean the same thing to all practitioners?If you have, then the following case vignette should provide theforum to discuss the evolution of some terms and help you decide how toapply them.

Understanding and quantifying the global methane (CH4) budget is important for assessing realistic pathways to mitigate climate change. CH4 is the second most important human-influenced greenhouse gas in terms of climate forcing after carbon dioxide (CO2), and both emissions and atmospheric concentrations of CH4 have continued to increase since 2007 after a temporary pause. The relative importance

Purpose of Review: Producing wood of the right quality is an important part of forest management. In the same way that forest growth models are valuable decision support tools for producing desired yields, models that predict wood quality in standing trees should assist forest managers to make quality-influenced decisions. A challenge for wood quality (WQ) models is to predict the properties of po

The concept of genre is scrutinized as a semantic phenomenon, and it is argued that the concept of genre must be defined according to a pragmatic semantic, not a realistic. Genres are not logical classes. The analytic practice is then connected to this way of defining the concepts: it is governed by how the culture using the concept understands the word. An analysis of a letter of Mme de Sévigné d

An implementation of a self-tuning regulator is described. The regulator algorithm consists of two steps. Firstly the parameters of a model of the process are estimated in real time using the method of least squares. Secondly a minimum variance regulator based on the estimated parameters is computed at each sampling interval. Implementation of the algorithm on a process computer is discussed. Ques

Background Trauma is the leading cause of quality-related mortality in low- and middle-income countries, with an estimated two million preventable deaths each year. Although trauma quality improvement programmes have been utilised in high-income countries for more than three decades, there is no high-level evidence of their effect on patient outcomes. We aimed to assess whether implementing a cont

The relative complexity of the mechanisms underlying savanna ecosystem dynamics, in comparison to other biomes such as temperate and tropical forests, challenges the representation of such dynamics in ecosystem and Earth system models. A realistic representation of processes governing carbon allocation and phenology for the two defining elements of savanna vegetation (namely trees and grasses) may

P>1. Sex ratios in unisexual bryophytes are most often female biased, whereas male-biased sex ratios predominate in unisexual seed plants. This 'bryophyte paradox', i.e. that sex ratios are biased in favour of the sex associated with the highest reproductive costs, has remained unexplained. 2. Analysis of sex-ratio patterns via the influence of sex distribution on population growth rates (lambda)

Previous research on violence during the war in Bosnia and Herzegovina has resulted in a one-sided presentation of the phenomenon of “war violence.” Researchers have emphasized the importance of narratives in general but have not analyzed stories on war violence that were the product of interpersonal interaction and meaning-making activity. The aim of this article is to fill this knowledge gap by

In selecting cows for higher milk yields and milk quality, it is important to understand how these traits are affected by the bovine genome. The major milk proteins exhibit genetic polymorphism and these genetic variants can serve as markers for milk composition, milk production traits, and technological properties of milk. The aim of this study was to investigate the relationships between casein