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Carrying capacity, a concept entrenched in the natural resources and environmental field for nearly two centuries, has continually evolved to address the conflicts and sustainability of the human- nature relationship. This paper introduces an analytical framework for understanding carrying capacity within the context of the human- nature relationship. It systematically reviews the progression of i
Fire-Induced Radiological Integrated Assessment : Fire properties of selected materials and products in reduce oxygen conditions
Characterization of emissions from fires in a laboratory-controlled environment are presented in this report. The project is initiated by the CERN HSE Unit and is called FIRIA, Fire-Induced Radiological Integrated Assessment. The objective of FIRIA is to enhance the knowledge of aerosols emitted from fires in order to develop dispersion models of radiologically-activated material in case of fire.
Rare-variant collapsing and bioinformatic analyses for different types of cardiac arrhythmias in the UK Biobank reveal novel susceptibility loci and candidate amyloid-forming proteins
Background: Cardiac arrhythmias are a common health problem. Both common and rare genetic risk factors exist for cardiac arrhythmias. Cardiac amyloidosis is a rare disease that may manifest various arrhythmias. Few large-scale whole exome sequencing studies elucidating the contribution of rare variations to arrhythmias have been published. Objective: To access gene collapsing analysis of rare vari
All-Cause and Cause-Specific Mortality in Tourette Syndrome and Chronic Tic Disorder
Background: Tourette syndrome (TS) and chronic tic disorder (CTD) may be associated with an increased risk of mortality, but specific causes of death are poorly understood. Objectives: In this matched cohort and sibling cohort study, we estimated the risk of all-cause and cause-specific mortality in individuals with TS/CTD, compared with unaffected matched individuals and unaffected full siblings.
Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated in situ gene labeling
The activity-regulated cytoskeleton-associated (Arc) protein is essential for synaptic plasticity and memory formation. The Arc gene, which contains remnants of a structural GAG retrotransposon sequence, produces a protein that self-assembles into capsid-like structures harboring Arc mRNA. Arc capsids, released from neurons, have been proposed as a novel intercellular mechanism for mRNA transmissi
Shorter Recovery Time in Concussed Elite Ice Hockey Players by Early Head-and-Neck Cooling : A Clinical Trial
A sports-related concussion (SRC) is most commonly sustained in contact sports, and is defined as a mild traumatic brain injury. An exercise-induced elevation of core body temperature is associated with increased brain temperature that may accelerate secondary injury processes following SRC, and exacerbate the brain injury. In a recent pilot study, acute head-neck cooling of 29 concussed ice hocke
Lower Frequency of Comorbidities Prior to Onset of Giant Cell Arteritis : A Population-Based Study
OBJECTIVE: To assess the frequency of comorbidities and metabolic risk factors at and prior to giant cell arteritis (GCA) diagnosis. METHODS: This is a retrospective case control study of patients with incident GCA between January 1, 2000, and December 31, 2019, in Olmsted County, Minnesota. Two age- and sex-matched controls were identified, and each assigned an index date corresponding to an inci
Balancing selection on the complement system of a wild rodent
Background: Selection pressure exerted by pathogens can influence patterns of genetic diversity in the host. In the immune system especially, numerous genes encode proteins involved in antagonistic interactions with pathogens, paving the way for coevolution that results in increased genetic diversity as a consequence of balancing selection. The complement system is a key component of innate immuni
High incidence of cardiovascular disease and increased prevalence of cardiovascular risk factors in women with hypopituitarism not receiving growth hormone treatment : preliminary results
Recently, epidemiological evidence has suggested that hypopituitarism with untreated growth hormone deficiency (GHD) is associated with a high incidence of cardiovascular mortality and that women are particularly at risk. In the present study, the incidence of cardiovascular disease and prevalence of cardiovascular risk factors in 33 such women was assessed and compared with matched controls. A si
Introducing Service-level Awareness in the Cloud
Managing the resources of a virtualized data-center is a key issue in cloud computing. Existing research mostly assumes that applications are either allocated the required resources or fail. Combined with the fact that most cloud applications have dynamic resource requirements, this imposes a fundamental limitation to cloud computing: To guarantee on-demand resource allocations, the data-center ne
Energy Policy Instruments and Innovation: How can tradable permit schemes influence innovation processes?
Gender and Critical Animal Studies : Potentials and Possible Tensions
Milk and Money
ROBUST ROTATION AND TRANSLATION ESTIMATION IN STRUCTURE FROM MOTION
Due to advances in technology the amount of images from portable cameras has increased tremendously in recent years. Nowadays, most new mobile phones and cars have multiple cameras. Drones and other robots are often equipped with cameras as well. To be able to capture an image is not the same as to understand the content of it. Computer vision deals with the task of giving machines the ability to
The effects of pre-aeration and inoculation on solid-state anaerobic digestion of rice straw
Pre-aeration was investigated for enhancing biodegradation of recalcitrant lignocellulosic structure of rice straw under various low temperatures regimes (25, 35 and 45 °C) and aeration durations (0, 2, 4, 6 and 8 days). It was demonstrated aerated rice straw for 2 days at 35 °C resulted in highest hydrolytic efficiency and biochemical methane potential (BMP) (355.3 ± 18.7 ml CH4/gVS). Furthermore
10qs ipsc
10 Questions: Clinical Outlook for iPSCs Cell Stem Cell Forum 10 Questions: Clinical Outlook for iPSCs Cell Stem Cell Editorial Team1,* 1Cell Stem Cell, Cell Press, 50 Hampshire Street, 5th Floor, Cambridge, MA 02139, USA *Correspondence: stemcell@cell.com http://dx.doi.org/10.1016/j.stem.2016.01.023 In an interview, we recently asked four leaders in the field to share their insights with us on th
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/10qs_ipsc.pdf - 2026-05-23
Automated deep learning segmentation of high-resolution 7 Tesla postmortem MRI for quantitative analysis of structure-pathology correlations in neurodegenerative diseases
Postmortem MRI allows brain anatomy to be examined at high resolution and to link pathology measures with morphometric measurements. However, automated segmentation methods for brain mapping in postmortem MRI are not well developed, primarily due to limited availability of labeled datasets, and heterogeneity in scanner hardware and acquisition protocols. In this work, we present a high-resolution
Discrete line spectroscopy at the extremes of angular momentum in normal deformed 156Dy and global differential lifetime measurements in the A ∼ 130 highly-deformed region
Elevated psychiatric and substance use disorders in people with intellectual disabilities in a Swedish National Sample
Background. Adults with intellectual disability (ID) experience marked mental health inequities, yet population-wide estimates that capture both primary- and specialist-care diagnoses remain scarce. Methods. Using nationwide Swedish registries, including primary care, specialist, inpatient, prescription drug, criminal, and suspicion registers, we included all individuals born in Sweden between 195
