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The actions and interactions of family genetic risk scores for alcohol use disorder and major depression on the risk for these two disorders

We know little about how genetic risk factors for two disorders jointly act and interact in predisposing to illness. Therefore, in the Swedish population, born 1970–1990 (n = 2,116,082) and followed through 2015, we examine, using additive Cox models, the impact of the family genetic risk scores (FGRS) for alcohol use disorder (AUD) and major depression (MD), their interaction with each other and

Genetic Landscape of the ACE2 Coronavirus Receptor

Background: SARS-CoV-2, the causal agent of COVID-19, enters human cells using the ACE2 (angiotensin-converting enzyme 2) protein as a receptor. ACE2 is thus key to the infection and treatment of the coronavirus. ACE2 is highly expressed in the heart and respiratory and gastrointestinal tracts, playing important regulatory roles in the cardiovascular and other biological systems. However, the gene

Cold sensitivity and its association to functional disability following a major nerve trunk injury in the upper extremity—A national registry-based study

Aims To investigate self-reported cold sensitivity and functional disability after a repaired major nerve trunk injury in the upper extremity. Methods We identified 735 individuals with a major nerve trunk injury in the upper extremity, surgically treated with direct nerve repair or reconstructed with nerve autografts, in the Swedish national quality registry for hand surgery (HAKIR). Patient-repo

ROBUST ROTATION AND TRANSLATION ESTIMATION IN STRUCTURE FROM MOTION

Due to advances in technology the amount of images from portable cameras has increased tremendously in recent years. Nowadays, most new mobile phones and cars have multiple cameras. Drones and other robots are often equipped with cameras as well. To be able to capture an image is not the same as to understand the content of it. Computer vision deals with the task of giving machines the ability to

The effects of pre-aeration and inoculation on solid-state anaerobic digestion of rice straw

Pre-aeration was investigated for enhancing biodegradation of recalcitrant lignocellulosic structure of rice straw under various low temperatures regimes (25, 35 and 45 °C) and aeration durations (0, 2, 4, 6 and 8 days). It was demonstrated aerated rice straw for 2 days at 35 °C resulted in highest hydrolytic efficiency and biochemical methane potential (BMP) (355.3 ± 18.7 ml CH4/gVS). Furthermore

Emission of thermally activated electrons from rare gas clusters irradiated with intense VUV light pulses from a free electron laser

The ionization dynamics of Ar and Xe clusters irradiated with intense vacuum ultraviolet light from a free-electron laser is investigated using photoelectron spectroscopy. Clusters comprising between 70 and 900 atoms were irradiated with femtosecond pulses at 95 nm wavelength (similar to 13 eV photon energy) and a peak intensity of similar to 4x10(12) W/cm(2). A broad thermal distribution of emitt

A harmonized country-level dataset to support the global stocktake regarding loss and damage from climate change

Under the Paris Agreement, parties should undertake a global stocktake of progress toward meeting the goals of the agreement and tackling climate change. The first global stocktake will be undertaken in 2023, and an assessment of loss and damage from climate change is an important part of the process. Loss and damage refer to the impacts of climate change felt when mitigation and adaptation effort

Imaging in gynecological disease (27) : clinical and ultrasound characteristics of recurrent ovarian stromal cell tumors

Objective: To describe the clinical and ultrasound characteristics of recurrent granulosa cell and Sertoli–Leydig cell tumors. Methods: This was a retrospective observational study performed at Fondazione Policlinico Universitario A. Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS, Rome (Gemelli center). Patients with a histological diagnosis of recurrent granulosa cell tumor o

Urban green spaces for urban farms and the sustainable development goals

The challenge of urbanisation, caused by an increase in city population, is increasing demand for imported food products. Food supplies may be impacted by the exponential increase in food demand caused by a constantly expanding global population. Growing and producing food in urban areas has now become a common practice. Addressing food system challenges through the adoption of urban farms on gree

Postoperative complications and emergency surgeries in colorectal cancer patients <50 years—a national cohort study

Aim: The incidence of colorectal cancer (CRC) in Sweden is increasing in individuals <50 years. This study aimed to examine differences in postoperative 30-day complications and rate of emergency surgeries in CRC patients <50 years at diagnosis compared to older age groups since population-based research on this topic is scarce. Method: This population-based study included data from the Swedish Co

Farmers’ motivations to cultivate biomass for energy and implications

Bioenergy derived from agricultural biomass can contribute to meeting the rising demand for renewable energy. To estimate the agricultural sector's potential to contribute to bioenergy, it is crucial to understand what motivates farmers to increase agricultural feedstock production sustainably. Through eight semi-structured interviews and online surveys with 174 farmers in southern Sweden, we expl

The impact of temperature and precipitation on all-infectious-, bacterial-, and viral-diarrheal disease in Taiwan

BACKGROUND: The ongoing climate change will elevate the incidence of diarrheal in 2030-2050 in Asia, including Taiwan. This study investigated associations between meteorological factors (temperature, precipitation) and burden of age-cause-specific diarrheal diseases in six regions of Taiwan using 13 years of (2004-2016) population-based data.METHODS: Weekly cause-specific diarrheal and meteorolog

Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum

Background: Proteolytic Clostridium botulinum is the causative agent of botulism, a severe neuroparalytic illness. Given the severity of botulism, surprisingly little is known of the population structure, biology, phylogeny or evolution of C. botulinum. The recent determination of the genome sequence of C. botulinum has allowed comparative genomic indexing using a DNA microarray. Results: Whole ge

Turbo Charged Low Temperature Combustion - Experiments, Modeling and Control

Popular Abstract in Swedish Ekonomin och välfärden är starkt beroende av tillförlitlig transport och energiförsörjningsteknologi. En stor del av denna teknik bygger på användandet av förbränningsmotorer. Då dessa till antalet är så stort utgör de tillsammans en stor miljöbelastning. Därför måste det läggas stora resurser på förbättrad motorstyrning och avgasrening. En av restprodukterna från förBoth the global economy and the society in general are dependent on the availability of reliable transportation. Most transportation technology involves the use of internal combustion engines in one way or another. Because of the large numbers of internal combustion engines in use around the world, their emissions have a significant environmental impact. Therefore, considerable efforts have been i

Structural and evolutionary studies of a lipocalin: the alpha1-microglobulin protein and its gene

Popular Abstract in Swedish INTRODUKTION Aminosyror är en grupp små molekyler som finns i våra celler. Totalt finns det tjugo olika aminosyror, vilka kan binda till varandra i långa kedjor varvid de bildar proteiner (äggviteämnen). Proteiner ansvarar för en lång rad funktioner i organismen och varje cell i en organism måste därför kunna syntetisera ett par tusen olika proteiner för att kroppen ska1-microglobulin is a small glycoprotein present in plasma and in tissues surrounding the gastrointestinal and respiratory tracts. a1-microglobulin is a member of the lipocalin protein family and exhibits several of the typical traits of a lipocalin; it binds an unknown ligand which causes the brown color of the protein, it forms complexes with various different proteins and there have been indica

Polysemy or generality? Mu

This chapter proposes a conception of lexical meaning as use-potential, in contrast to prevailing atomistic and reificational views. The issues are illustrated on the example of spatial expressions, pre-eminently prepositions. It is argued that the dichotomy between polysemy and semantic generality is a false one, with expressions occupying points on a continuum from full homonymy to full monosemy