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Unity in organisation and regulation of catabolic operons in Lactobacillus plantarum, Lactococcus lactis and Listeria monocytogenes

Global regulatory circuits together with more specific local regulators play a notable role when cells are adapting to environmental changes. Lactococcus lactis is a lactic acid bacterium abundant in nature fermenting most mono- and disaccharides. Comparative genomics analysis of the operons encoding the proteins and enzymes crucial for catabolism of lactose, maltose and threhalose revealed an obv

Ladyfest Sweden: a female cultural initiative

Ladyfest Sweden is a cultural festival which aims to create a cultural space of expression for women, thus the artists and the organizers are women. It is organized by three different groups in three different cities: Malmö, Stockholm and Göteborg. This thesis is focused on Ladyfest Malmö, all the field work being realized with this group. We tried to include this phenomenon in a global and a part

Man and Matter: A Philosophical Inquiry into the Justification of Ownership in Land from the Basis of Self-Ownership

This study seeks to investigate the nature of ownership of land and how the right to its control and use can be inferred from self-ownership as a premise. Hence, the question asked is how ownership (of land) can be justified considering the nature of man from a natural rights point of view. The starting point for the argument is self-ownership as being, where man is identified as an indivisible e

Mutation analysis of SLC7A9 in cystinuria patients in Sweden

Cystinuria is an autosomal recessive disorder characterized by increased urinary excretion of cystine and dibasic amino acids, which cause recurrent stone formation in affected individuals. Three subtypes of cystinuria have been described (type I, II, and III): type I is caused by mutations in the SLC3A1 gene, whereas nontype I (II and III) has been associated with SLC7A9 mutations. Of the 53 pati

Full Cycle Engine Simulations with Detailed Chemistry

Popular Abstract in Swedish Modelleringsarbetet utvecklat i denna avhandling, kan delas in i två huvudområden: självantändning i ottomotorer, samt förbränning och emissioner i dieselmotorer. En första version av ett motorsimuleringsprogram med detaljerad kemisk kinetik, utökad för att innefatta full-cykel beräkningar, användes för att visa den starka påverkan som kväveoxider i restgaser har på sjThe modeling work developed in this thesis can be divided in two main areas of investigations: autoignition related to spark ignition engine and combustion and emissions formation in relation to diesel engines. A first version of a detailed kinetics engine simulation program, extended to handle full cycle calculations, was employed in order to demonstrate the strong effect that nitric oxide from

Analysis of Computational Algorithms for Linear Multistep Methods

Linear multistep methods (LMMs) constitute a class of time-stepping methods for the solution of initial value ODEs; the most well-known methods of this class are the Adams methods (AMs) and the backward differentiation formulae (BDFs). For the fixed stepsize LMMs there exists an extensive error and stability analysis; in practical computations, however, one always uses a variable stepsize. It is w

Skyddsvärda intressen & straffvärda kränkningar. Om sexualbrotten i det straffrättsliga systemet med utgångspunkt i brottet sexuellt ofredande

Popular Abstract in Swedish I den här doktorsavhandlingen undersöker Linnea Wegerstad hur sexualbrott urskiljs från andra typer av våld och kränkningar i straffrätten. Författaren utforskar hur sedlighetsbrott blev till sexualbrott under första hälften av 1900-talet och hur ett särskilt skyddsvärt intresse då skapades: den sexuella integriteten. Genom att också undersöka lagstiftningsreformer frånWhat is considered a sexual offense and what constitutes the sexual integrity protected by Swedish criminal law? Through a comprehensive historical, theoretical and doctrinal analysis, this thesis considers the question of how distinctions between sexual and other forms of violence, abuse or harassment are made in criminal law. Firstly, the thesis explores the emergence of sexual offenses in the

Language and Literacy : Some fundamental issues in research on reading and writing

Abstract in Norwegian Hovudlina i forskinga på lesing og skriving byggjer på tanken om at talt språk på alle vesentlege punkt er primært i høve til skrive språk. Omgrepsapparatet for studiet av språk og lese- og skrivedugleik er også bygd kring denne tanken. Dette er problematisk frå eit vitskapsteoretisk standpunkt sidan tanken om det talte språket sin dominans ikkje er tilstrekkeleg empirisk undMainstream research on reading and writing is based on the assumption, common in modern linguistics, that spoken language is primary to written language in most important respects. Unfortunately, the conceptual framework for the study of language and 'literacy' (encompassing both reading and writing skills) is built around this assumption. This is problematic with regard to the philosophy of scien

Post-Genomic Update on a Classical Candidate Gene for Coronary Artery Disease: ESR1

Background-After age, sex is the most important risk factor for coronary artery disease (CAD). The mechanism through which women are protected from CAD is still largely unknown, but the observed sex difference suggests the involvement of the reproductive steroid hormone signaling system. Genetic association studies of the gene-encoding Estrogen Receptor alpha (ESR1) have shown conflicting results,

Primary and secondary diagnoses of gambling disorder and psychiatric comorbidity in the Swedish health care system-A nationwide register study

Background: Psychiatric comorbidity is common in gambling disorder, a condition with low rates of treatment seeking. There is a paucity of documented nationwide data on gambling disorder and its co-occurring psychiatric comorbidities in the health care system. Methods: This is a nationwide register-based study of all patients aged above 18 years who were diagnosed with gambling disorder (correspon

Open source ERP business model framework

ERP systems became popular with large organizations in the 1990s. In the 21st Century, these products were expanded by addition of supply chain management (SCM) and customer relationship management (CRM), as well as access through the Web, creating the ERP II concept. Efforts to increase the market led vendors to serve not only large organizations, but also focus more on small-to-medium sized ente

Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression

Introduction: Atopic asthma and allergic rhinitis are common chronic inflammatory diseases affecting lower airways and nasal mucosa, respectively. Several reports demonstrated frequent co-occurrence of these two diseases, however, the exact molecular mechanism has not been described. The present study aimed to investigate if small non-coding RNA might be responsible for the co-occurrence of asthma

Cloning of cDNA coding for the beta chain of human complement component C4b-binding protein : sequence homology with the alpha chain

The major form of complement component C4b-binding protein, a regulator of the complement system, is composed of seven identical 70-kDa alpha chains, each containing a binding site for the complement protein C4b. We recently showed that C4b-binding protein also contains a unique 45-kDa beta chain. It is disulfide-linked to the central core and contains a binding site for the vitamin K-dependent pr

Svensk Dagfjärilsövervakning, årsrapport för 2017

Detta är den åttonde årsrapporten från Svensk Dagfjärilsövervakning, ett nationellt miljö-övervakningsprogram som koordineras av Lunds universitet på uppdrag av Naturvårdsverket sedan 2010. Svensk Dagfjärilsövervakning är ett samarbete mellan Sveriges Entomologiska Förening, Naturvårdsverket, Lunds universitet, Sveriges lantbruksuniversitet och Länsstyrelserna. Verksamheten möjliggörs av frivillig

Svensk Dagfjärilsövervakning, årsrapport för 2018

Detta är den nionde årsrapporten från Svensk Dagfjärilsövervakning, ett nationellt miljöövervakningsprogram som koordineras av Lunds universitet på uppdrag av Naturvårdsverket sedan 2010. Svensk Dagfjärilsövervakning är ett samarbete mellan Sveriges Entomologiska Förening, Naturvårdsverket, Lunds universitet, Sveriges lantbruksuniversitet och Länsstyrelserna. Verksamheten möjliggörs av frivilliga

A harmonized country-level dataset to support the global stocktake regarding loss and damage from climate change

Under the Paris Agreement, parties should undertake a global stocktake of progress toward meeting the goals of the agreement and tackling climate change. The first global stocktake will be undertaken in 2023, and an assessment of loss and damage from climate change is an important part of the process. Loss and damage refer to the impacts of climate change felt when mitigation and adaptation effort

Balancing selection on the complement system of a wild rodent

Background: Selection pressure exerted by pathogens can influence patterns of genetic diversity in the host. In the immune system especially, numerous genes encode proteins involved in antagonistic interactions with pathogens, paving the way for coevolution that results in increased genetic diversity as a consequence of balancing selection. The complement system is a key component of innate immuni

Young men's behavioral competencies and risk of alcohol use disorder in emerging adulthood : Early protective effects of parental education

We investigate how early exposure to parental externalizing behaviors (EB) may contribute to development of alcohol use disorders (AUD) in young adulthood, testing a developmental cascade model focused on competencies in three domains (academic, conduct, and work) in adolescence and emerging adulthood, and examining whether high parental education can buffer negative effects of parental EB and oth