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Intrinsic molecular subtypes may explain marked variation between bladder cancer patients in prognosis and response to therapy. Complex testing algorithms and little attention to more prevalent, early-stage (non-muscle invasive) bladder cancers (NMIBCs) have hindered implementation of subtyping in clinical practice. Here, using a three-antibody immunohistochemistry (IHC) algorithm, we identify the

En hybridpark bestående av vind- och solkraft förbättrar vätgasproduktionens prestanda jämfört med ifall kraftslagen agerar separat och kan dela på samma infrastruktur. Detta examensarbete är en förstudie som granskar möjligheten för två vindkraftverk med en effekt på vardera 2 MW att kompletteras med en solcellspark för att bilda en hybridpark med vätgasproduktion. Förstudien undersöker dess teknA hybrid power plant (HPP) existing of wind- and solar power improves the performance of the hydrogen production compared to the stand-alone alternative and can share infrastructure. This thesis views the possibility for two wind turbines with 2 MW power each to be combined with solar power to form a HPP with hydrogen production. The thesis investigates the plant’s technical, economic and permits

Partially Premixed Combustion (PPC) is an internal combustion engine concept that aims to yield low NOx and soot emission levels together with high engine efficiency. PPC belongs to the class of low temperature combustion concepts where the ignition delay is prolonged in order to promote the air-fuel-mixture homogeneity in the combustion chamber at the start of combustion. A more homogeneous combu

Popular Abstract in Swedish De ökande kraven på högre datahastigheter inom trådlös kommunikation ställer allt högre krav på både radiosändare och mottagare, då dessa behöver utnyttja fler frekvensband med större bandbredd vid högre frekvenser. Fokus i denna avhandling ligger på högfrekvensdelen av radiomottagaren, som består av lågbrusförstärkare, blandare, och oscillatorer vid mikrovågsfrekvenserThe increasing demand for high data rates in wireless communication systems is increasing the requirements on the transceiver front-ends, as they are pushed to utilize more and wider bands at higher frequencies. The work in this thesis is focused on receiver front-ends composed of Low Noise Amplifiers (LNAs), Mixers, and Voltage Controlled Oscillators (VCOs) operating at microwave frequencies. Tra

Popular Abstract in Swedish Avhandlingen består av fyra uppsatser som handlar om individers hälsorelaterade beteende och investeringar i högre utbildning. Tre av uppsatserna fokuserar på olika aspekter av läkemedelsanvändning och syftar till att förklara varför individer med liknande medicinska behov är olika benägna att använda receptbelagda läkemedel. Den fjärde uppsatsen studerar hälsans betydeThis thesis consists of four essays on individual health behaviour and investment in higher education. Three of them consider different aspects of pharmaceutical utilization and aim at explaining some of the observed individual variation in access and adherence to treatment regimens. The fourth explores the potential link from health in young adulthood to subsequent university education. The firs

Object. Cerebral vasospasm following subarachnoid hemorrhage (SAH) leads to reduced blood flow in the brain. Inspired by organ culture-induced changes in the receptor phenotype of cerebral arteries, the authors investigated possible changes in the 5-hydroxytryptamine (HT) receptor phenotype after experimental SAH. Methods. Experimental SAH was induced in rats by using an autologous prechiasmatic i

The Swedish Antarctic Research Expedition named “SWEDARP” was performed during October 1988 through April 1989. The aim of our project was to study the radioactivity in air and water from Gothenburg to the Antarctic. Between Gothenburg and the Equator, the average activity concentration of 7Be in air was 4.3 ± 0.7 mBq/m3. The activity concentration of 7Be in the South Atlantic down to Antarctica v

Popular Abstract in Swedish En av de största orsakerna till svårt handikapp och död i västvärlden är traumatisk hjärnskada som uppstår till följd av våld mot huvudet. Utav vuxna och barn är det generellt sett barn som klarar sig bättre efter våld mot huvudet men det är ändå till stor del barn som söker akutmottagning p.g.a. skallskada. De flesta av barnen har en så kallad lätt skallskada (ca 90 %)Traumatic head injury is one of the leading causes to severe morbidity and death among children. Specific and national management guidelines for pediatric head injuries are lacking in Sweden, and management routines are consequently based on adult guidelines or local guidelines. The objectives of this thesis were to investigate the current management of pediatric head injury in Sweden and to explo

Introduction: Depression is frequent in ankylosing spondylitis (AS) patients. However, epidemiological data about the potential increase in risk are lacking. This study compares the rate of doctor-diagnosed depression in a well defined cohort of AS patients to the general population seeking care. Methods: The Skane Healthcare Register comprises healthcare data of each resident in Region Skane, Swe

In birds the major histocompatibility complex (MHC) organization differs both among and within orders; chickens Gallus gallus of the order Galliformes have a simple arrangement, while many songbirds of the order Passeriformes have a more complex arrangement with larger numbers of MHC class I and II genes. Chicken MHC genes are found at two independent loci, classical MHC-B and non-classical MHC-Y,

Protein affinity reagents (PARs), most commonly antibodies, are essential reagents for protein characterization in basic research, biotechnology, and diagnostics as well as the fastest growing class of therapeutics. Large numbers of PARs are available commercially; however, their quality is often uncertain. In addition, currently available PARs cover only a fraction of the human proteome, and thei

Today, as a rule, the most cost-effective way to remove nitrogen from municipal wastewater is the biological method based on nitrification and subsequent denitrification. All biological systems may be affected by toxicants, and biological nitrogen removal is no exception. An investigation of influent wastewaters from 109 Swedish municipal wastewater treatment plants was accomplished. Inhibitory s

The aim of this paper is to analyse the role that the Japanese Government has played in the development of alternatives to conventional vehicles, the effect of government programmes, and the importance of technical flexibility in government support schemes. The focus is on battery-powered electric vehicles (BPEVs), hybrid electric vehicles (HEVs), and fuel cell electric vehicles. The effects of go

We have made in-situ investigations of ultrathin films of Fe grown on a Ag(100) single crystal. This system is known to exhibit a reorientation of the magnetization, dependent on both Fe thickness and temperature. X-ray absorption fine structure has been recorded for samples prepared in-situ, both in the near edge and in the extended x-ray absorption fine structure (EXAFS) region. Using x-ray magn

Popular Abstract in Swedish Denna avhandling utgör den första delen i en planerad serie på tre rapporter med utgångspunkt i data insamlade läsåret 1993/94 i årskurs 9 vid en grundskola, där det lokala skolprojektet Tonåringens livssituation och livstolkning genomförts i ämnet religionskunskap. Det övergripande syftet med studien är att undersöka vilka centrala livsvärden eleverna ger uttryck för iThis dissertation makes up the first report based on data collected during the project "Teenagers: aspects of their life style and attitudes" (Tonåringens livssituation och livstolkning) in the subject Religious Studies taken by pupils attending Year 9 during the 1993/94 school year. The general aim of the study is to discover the central values of life which pupils hold, as expressed in an essay

Popular Abstract in Swedish Syftet har varit att studera tillämpningen av ventilation i skolbyggnader. Huvuddelen av avhandlingen behandlar vädring av klassrum. Analytiska modeller med vilka luftutbytet orsakat av vädring kan beräknas föreslås. Ett mål är att modellerna skall utgöra ett verktyg för projektörer och brukare. Modellerna skall kunna användas när man vill bestämma tidslängden för vädriThe objective of this thesis is to study the application of ventilation in schools buildings. A number of studies of the application of different forms of ventilation are presented. The main part of the thesis focuses on window opening in a classroom. Analytical models for calculation of the air change caused by window airing are proposed. The models are intended to be a tool for designers and occ

Lack of carbon has been assumed to be the most common limiting factor for bacterial growth in soil, although there are reports of limitation by nitrogen and phosphorus. I have studied nutrient limitation of bacterial growth in soil using a novel technique, where thymidine or leucine incorporation is used to detect changes in growth rates after adding nutrients. I have studied which nutrient(s) li

Popular Abstract in Swedish Nanotrådar har potential att bli en mycket flexibel plattform för design av halvledarkomponenter. I nanotrådar är det möjligt att bilda kristallstrukturer som normalt sett inte förekommer i bulkmaterial, och att kombinera olika III-V och grupp IV material i axiella eller radiella heterostrukturer. Eftersom så pass komplicerade strukturer kan skapas, både avsiktligt och Nanowires have the potential to be a very flexible platform for the design of semiconductor devices. In nanowires it is possible to form crystal structures not found in the bulk materials under normal conditions, and to combine different III-V and group IV materials into axial or radial heterostructures. As quite complex structures can be formed, both intentionally and unintentionally, characteriz

Packaging Logistics is a concept that recognises the need for coordination of the packaging system and its manifold functions throughout a package’s life cycle. Packaging Logistics is an area in need for substantial theoretical building. This dissertation elaborates on its underpinnings and suggests conceptual models that should be useful in better understanding the core of the concept, its undere