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In SPECT imaging of pure beta emitters, such as (90)Y, the acquired spectrum is very complex, which increases the demands on the imaging protocol and the reconstruction. In this work, we have evaluated the quantitative accuracy of bremsstrahlung SPECT with focus on the reconstruction algorithm including model-based attenuation, scatter and collimator-detector response (CDR) compensations. The scat

Abstract Objective. To evaluate the prevalence of primary aldosteronism (PA) in newly diagnosed and untreated hypertensive patients in primary care using the aldosterone/renin ratio (ARR), and to assess clinical and biochemical characteristics in patients with high and normal ARR. Design. Patient survey study. Setting and subjects. A total of 200 consecutive patients with newly diagnosed and untre

INTRODUCTION: D-dimer assays are now widely used as the first-line test in the diagnostic algorithm of suspected deep vein thrombosis (DVT). The aim of this study was to evaluate the performance of two relatively new quantitative D-Dimer assays (Innovance and AxSYM(R)) by comparison with a clinical gold standard. PATIENTS AND METHODS: 311 samples from outpatients with clinical suspicion of DVT, in

Popular Abstract in Swedish Det är känt att låg socioekonomisk position (t.ex., låg inkomst, kort utbildning) och civilstånd, (t.ex., ensamstående) kan försämra hälsan. Den sämre hälsan medför ett ökat sjukvårdsbehov, och i ett jämlikt samhälle borde därför sjukvårdsutnyttjandet vara större bland de med låg socioekonomisk position och bland de som är ensamstående. Av samma anledning bör en högre f

Background: p21-activated kinase 1 (Pak1) phosphorylates many proteins in both normal and transformed cells. Its ability to phosphorylate and thereby activate the estrogen receptor alpha (ER alpha) potentially limits the effectiveness of antiestrogen treatment in breast cancer. Here we studied associations between Pak1 expression and subcellular localization in tumor cells and tamoxifen resistance

Abstract Purpose: To evaluate the midterm outcomes and potential risk factors associated with the fascia suture technique (FST) for closure of femoral artery access sites after percutaneous endovascular aneurysm repair (EVAR). Methods: Between April 2007 and April 2008, 100 consecutive EVAR cases were evaluated retrospectively. A third of the procedures were emergent (16 ruptured aneurysms). Of th

Givet ett harmoniskt vektorfält u på en begränsad domän kallar vi den mängd där u träder in i domänen för inträdesrand och den mängd där u lämnar domänen utträdesrand. I den första delen av detta examensarbete ställer vi frågan om det är möjligt att ha inre stagnationspunkter och sammanhängande inträdes- och utträdesrand. Svaret i två dimensioner är ‘nej’ för en domän som är homeomorf till skivan.Given a harmonic vector field u on a bounded domain we call the set on which u enters the domain entrant boundary and the set on which u exits the domain emergent boundary. In the first part of this thesis we ask the question of whether it is possible to have interior stagnation points and connected entrant and emergent boundaries. The answer in two dimensions for a domain homeomorphic to a disc i

This study explores how older adults in Copenhagen experience the transition into empty-nest life within the broader context of Denmark’s welfare system and cultural values. Using a mixed-method approach, including surveys, in-depth interviews, home visits and walk-along observations, the study investigates perceptions of the respondents concerning how Denmark’s strong welfare system, community en

Grass pollen allergens, including Phl p 5 from Phleum pratense, are major triggers of seasonal allergic rhinitis, primarily mediated by IgE antibodies. This study investigates the genetic basis and functional characteristics of IgG1 antibodies targeting Phl p 5, possibly derived from type 2 memory B cells predisposed to IgE switching. Using site-directed mutagenesis, we analyzed variants of a high

This thesis investigates particulate matter emissions from a turbofan jet engine operated with fossil Jet A fuel and mixtures of Jet A and sustainable aviation fuel (SAF), focusing on particle size distributions and total emission concentrations. The aim was to evaluate emissions from different fuel blends and sampling points, assess the performance of the designed sampling and dilution system, an

Motor sequence learning research has been primarily concerned with simple frequentist patterns, thereby neglecting the motor system's ability to handle uncertainty and non-deterministic environments. In this study, we combine methods from motor neuroscience and neurolinguistics to study how probabilistic systems are acquired during motor learning. Two groups of young adults practiced a probabilist

Detta arbete har syftat till att göra en situationsstudie av dissipation beräknad i HIRLAM, en numerisk prognosmodell, över Danmark och att ge författarna kunskap om fenomenet turbulens. Studien gjordes genom att bearbeta data erhållen från HIRLAM i MATLAB. Den nedersta delen av troposfären där jordytan har en påverkan på atmosfären kallas för gränsskiktet. När vinden blåser i gränsskiktet kommer This case study aimed at analyzing dissipation calculated in HIRLAM, a numerical forecast model, over Denmark and to give the authors more knowledge about the phenomenon of turbulence. The study was done by processing data obtained from HIRLAM in MATLAB. The lowest part of the troposphere where the surface of the earth has an impact on the air is called the planetary boundary layer. When the wind

The main goal of this thesis is to find out, what is a complicated product and if complicated products can be more simplified in their properties, which are these properties and finally to incorporate these properties in the design of an object. The final design will be carried out in a full scale model to understand and test the implemented properties of simplification directly on the product in

This research investigates short-term management fixation to meet performance thresholds through real earnings management. Specifically, we examine management decision-making regarding the trade-off between short-term profitability and R&D’s long-term benefits in Nordic firms. Building on established economic and institutional frameworks, along with the most relevant studies in the field, this

Background: The 10-m walk test (10MWT) is a widely used measure of gait speed in Parkinson’s disease (PD). However, it is unclear if different standardizations of its conduct impact test results. Aim of the study: We examined the clinical significance of two aspects of the standardization of the 10MWT in mild PD: static vs. dynamic start, and a single vs. repeated trials. Implications for fall pre

In the era of large-scale surveys of stars in the MilkyWay, stellar ages are crucial for studying the evolution of the Galaxy.But determining ages of field stars is notoriously difficult; therefore, we attempt to determine benchmark ages for the extensively studied Gaia benchmark stars which can be used for validation purposes. By searching the literature for age estimates from different methods a

Mutations are not identified in ~5% of hemophilia A and 10-35% of type 1 VWD patients. The bleeding tendency also varies among patients carrying the same causative mutation, potentially indicating variants in additional genes modifying the phenotype that cannot be identified by routine single-gene analysis. The F8, F9 and VWF genes were analyzed in parallel using an AmpliSeq strategy and Ion Torre

Amyloids are implicated in many diseases, and disruption of lipid membrane structures is considered as one possible mechanism of pathology. In this paper we investigate interactions between an aggregating peptide and phospholipid membranes, focusing on the nanometer-scale structures of the aggregates formed, as well as on the effect on the aggregation process. As a model system, we use the small a

Metastatic castration-resistant prostate cancer is today incurable. Conventional imaging methods have limited detection, affecting their ability to give an accurate outcome prognosis, and current therapies for metastatic prostate cancer are insufficient. This inevitably leads to patients relapsing with castration-resistant prostate cancer. Targeting prostate-specific antigens whose expression is c