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The role of the rhabdosphincter in female rat voiding

Objectves To obtain information on the mechanisms of female rat micturition using a model in which pressure was measured in the bladder and distal part of the urethra corresponding to the location of the rhabdosphincter, providing information on the role of the sphincter in opening and closing the urethral lumen. Materials and Methods A micturition reflex was induced in adult anaesthetized (chlora

Blood volume assessment with hemoglobin subtype analysis in preterm infants

The aim of the study was to assess plasma volume (PV) and red cell volume (RCV) in preterm infants with a liquid chromatographic hemoglobin subtype method (HbST) based on dilution of autologous fetal hemoglobin (HbF) by donor adult hemoglobin and measurement of the amount of HbF. PV determination with the indocyanine green dye dilution technique (ICG) was used as a reference method. Eight infants,

Skipping the Baltic: the emergence of a dichotomy of alternative spring migration strategies in Russian barnacle geese

Since the early 1990s, an increasing proportion of barnacle geese, Branta leucopsis, bound for breeding sites in the Russian Arctic delay their departure from the wintering quarters in the Wadden Sea by 4 weeks. These late-migrating geese skip spring stopover sites in the Baltic traditionally used by the entire population. Individual geese from an arctic colony tracked by satellite or light-level

The influence of production systems on physiological responses measured in urine and saliva

The aim of the present study was to investigate physiological effects of highly similar production systems with different degrees of automation by use of urinary catecholamines and cortisol as well as salivary cortisol. Furthermore, it was determined whether the physiological response was related to real-time self-reports in terms of feelings of positive and negative arousal, physical exertion, an

Fe II emission spectra in AGN: observations and theoretical interpretation

The enrichment of Fe, relative to alpha elements such as O and Mg, represents a potential means to measure the ages of quasi-stellar object (QSO) host galaxies and probe nucleosynthesis in the early universe. QSOs exhibit prominent Fe II features and Mg II 2800 angstrom resonance doublet emission in the ultraviolet. Although chemical evolutionary models predict that the Fe/Mg abundance ratio decre

Growth and interactions of arbuscular mycorrhizal fungi in soils from limestone and acid rock habitats

Arbuscular mycorrhizal (AM) development in different soil types, and the influence of AM fungal hyphae on their original soil were investigated. Plantago lanceolata, which can grow in soils of a very wide pH range, was grown in two closely related limestone soils and an acid soil from rock habitats. Plants were colonised by the indigenous AM fungal community. The use of compartmented systems allow

Combined magnetic and structural investigation of nano crystalline iron oxides: The interplay between crystal size and phase composition during FeS2 oxidation

The oxides that form during thermal oxidation of natural FeS2 (pyrite and marcasite) consist of nanometer-sized crystals of alpha-Fe2O3 and gamma-Fe2O3. This is shown with heating experiments that were made up to 650 degrees C, which resembles temperatures used in metallurgical processes. It is shown that magnetic measurements can play a key role in the investigation of this reaction, due to the u

Hearing and evasive behaviour in the greater wax moth, Galleria mellonella (Pyralidae)

Greater wax moths (Galleria mellonella L., Pyraloidea) use ultrasound sensitive ears to detect clicking conspecifics and echolocating bats. Pyralid ears have four sensory cells, A14. The audiogram of G. mellonella has best frequency at 60 kHz with a threshold around 47 dB sound pressure level. A1 and A2 have almost equal thresholds in contrast to noctuids and geometrids. A3 responds at + 12 to + 1

Human stem cell‐derived gabaergic interneurons establish efferent synapses onto host neurons in rat epileptic hippocampus and inhibit spontaneous recurrent seizures

Epilepsy is a complex disorder affecting the central nervous system and is characterised by spontaneously recurring seizures (SRSs). Epileptic patients undergo symptomatic pharmacolog-ical treatments, however, in 30% of cases, they are ineffective, mostly in patients with temporal lobe epilepsy. Therefore, there is a need for developing novel treatment strategies. Transplantation of cells releasin

Humanization, radiolabeling and biodistribution studies of an igg1-type antibody targeting uncomplexed psa for theranostic applications

Metastatic castration-resistant prostate cancer is today incurable. Conventional imaging methods have limited detection, affecting their ability to give an accurate outcome prognosis, and current therapies for metastatic prostate cancer are insufficient. This inevitably leads to patients relapsing with castration-resistant prostate cancer. Targeting prostate-specific antigens whose expression is c

FPGA Implementation of In-Cycle Closed-Loop Combustion Control Methods

This paper investigates the FPGA resources for the implementation of in-cycle closed-loop combustion control algorithms. Closed-loop combustion control obtains feedback from fast in-cylinder pressure measurements for accurate and reliable information about the combustion progress, synchronized with the flywheel encoder. In-cycle combustion control requires accurate and fast computations for their

Short-term effects of a computer-based nutritional nursing training program for inpatient hospital care

RATIONALE: This study aimed to explore whether a computer-based training in eating and nutrition for hospital nursing staff can influence the precision in nutritional treatment and care.METHOD: A pre-intervention and post-intervention study was conducted with a cross-sectional design at each time point. The settings were one intervention (IH) and two control hospitals (CH1 and CH2). Hospital inpat

Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma

Neoantigens are now recognized drivers of the antitumor immune response. Recurrent neoantigens, shared among groups of patients, have thus become increasingly coveted therapeutic targets. Here, we report on the data-driven identification of a robustly presented, immunogenic neoantigen that is derived from the combination of HLA-A*01:01 and RAS.Q61K. Analysis of large patient cohorts indicated that

Elevated temperatures increase growth and enhance foraging performances of a marine gastropod

The oceans continue to warm due to rising atmospheric greenhouse gas concentrations. Most climate-change studies of aquaculture species use temperature changes based on coarse-resolution climate models and without considering thermal ranges of an animal. Coarse-resolution climate models are generated by global-scale data, which is insufficient to capture the conditions of coastal areas where most

Nutrient limitation may induce microbial mining for resources from persistent soil organic matter

Fungi and bacteria are the two principal microbial groups in soil, responsible for the breakdown of organic matter (OM). The relative contribution of fungi and bacteria to decomposition is thought to impact biogeochemical cycling at the ecosystem scale, whereby bacterially dominated decomposition supports the fast turnover of easily available substrates, whereas fungal-dominated decomposition lead

Factors influencing late-Holocene vegetation dynamics and biodiversity on Hallands Väderö, SW Sweden : A statistical evaluation

Forest composition characteristic of the Mid-Holocene has survived on Hallands Väderö, an island nature reserve off the south west coast of Sweden. Current veteran Tilia and Quercus trees contribute to a remarkably rich biodiversity of fungi, bryophytes, lichens and insects. Understanding which potential factors influence Holocene vegetation dynamics can support efforts to protect biodiversity, bu

Base-catalyzed depolymerization of kraft lignin for valuable chemical production

Lignin is one of the three predominant biopolymers that make up plants together with cellulose and hemicellulose, and it is the only plant component that is based on aromatic units. The industrial kraft pulping process generates large amounts of lignin, which is currently used to generate heat for the process. The subject of this thesis is the valorization of kraft lignin into valuable chemicals.

Simulation of thermal and mechanical performance of laser cladded disc brake rotors

Disc brakes wear during braking events and release airborne particulates. These particle emissions are currently one of the highest contributors to non-exhaust particle emissions and introduce health hazards as well as environmental contamination. To reduce this problem, wear and corrosion-resistant disc coatings have been implemented on grey cast iron brake disc rotors by using various deposition

Effect of Shortening the Scan Duration on Quantitative Accuracy of [18F]Flortaucipir Studies

Purpose: Dynamic positron emission tomography (PET) protocols allow for accurate quantification of [18F]flortaucipir-specific binding. However, dynamic acquisitions can be challenging given the long required scan duration of 130 min. The current study assessed the effect of shorter scan protocols for [18F]flortaucipir on its quantitative accuracy. Procedures: Two study cohorts with Alzheimer’s dis